Notification of transaction by Person Discharging Managerial Responsibilities ("PDMR")

 __________________________________________________________________________
|1 |Details of the person discharging managerial responsibilities/person   |
|  |closely associated                                                     |
|__|_______________________________________________________________________|
|a)|Name                                    |Jane Kirton                   |
|__|________________________________________|______________________________|
|2 |Reason for the notification                                            |
|__|_______________________________________________________________________|
|a)|Position/status                         |Company Secretary             |
|__|________________________________________|______________________________|
|b)|Initial notification/Amendment          |Initial notification          |
|__|________________________________________|______________________________|
|3 |Details of the issuer, emission allowance market participant, auction  |
|  |platform, auctioneer or auction monitor                                |
|__|_______________________________________________________________________|
|a)|Name                                    |Pensana Plc                   |
|__|________________________________________|______________________________|
|b)|LEI                                     |213800H4QP6T9499RU64          |
|__|________________________________________|______________________________|
|  |Details of the transaction(s): section to be repeated for (i) each type|
|4 |of instrument; (ii) each type of transaction; (iii) each date; and (iv)|
|  |each place where transactions have been conducted                      |
|__|_______________________________________________________________________|
|a)|Description of the financial instrument,|Ordinary Shares of £0.001 each|
|  |type of instrument                      |                              |
|__|________________________________________|______________________________|
|  |Identification code                     |GB00BKM0ZJ18                  |
|__|________________________________________|______________________________|
|b)|Nature of the transaction               |Purchase of shares            |
|__|________________________________________|______________________________|
|  |                                        |Price: £0.2486                |
|c)|Price(s) and volume(s)                  |                              |
|  |                                        |Volume: 603                   |
|__|________________________________________|______________________________|
|  |                                        |Aggregated volume: 603        |
|  |                                        |                              |
|d)|Aggregated information                  |Aggregated Price: £0.2486     |
|  |                                        |                              |
|  |                                        |Aggregated Total: £149.91     |
|__|________________________________________|______________________________|
|e)|Date of the transaction                 |5 November 2024               |
|__|________________________________________|______________________________|
|f)|Place of the transaction                |London Stock Exchange         |
|__|________________________________________|______________________________|