ImmunoPrecise Antibodies (IPA) Reports Full Fiscal Year 2025 Results, Record Fourth Quarter Revenue, and Record Fourth Quarter Adjusted EBITDA
Financial Highlights:
-
Achieved strong revenue for Fiscal Year 2025 of
$24.5 million -
Delivered highest-ever fourth quarter revenue of
$7.0 million -
Reported record fourth quarter Adjusted EBITDA of
($0.3) million , reflecting improved operating efficiency - Achieved fourth quarter gross margin of 64%, up from 48% from Q4 FY24
- BioStrand segment grew over 180% in Fiscal year 2025 and had gross margins approaching 90%
- BioStrand currently represents over 5% of total annual revenue this year, up from less than 2% in Fiscal Year 2024
Recent Corporate Highlights:
- The Company’s LENSai™ platform demonstrated that it’s in silico epitope mapping achieves results on previously unseen antibody–antigen complexes with results that are on par with gold-standard X-ray crystallography—yet delivering structural insights in hours instead of weeks.
- An important breakthrough using the Company's HYFT®-powered LENSai platform, as it identified a highly conserved epitope across all four dengue virus serotypes, a key milestone toward developing a potential universal dengue vaccine. Subsequently announced in silico data supporting the vaccine candidate's safety and its ability to activate a balanced immune response.
- IPA’s AI-designed GLP-1 peptides outperformed or matched semaglutide in independent receptor activation studies, further validating the Company’s HYFT-driven LENSai platform.
- Entered a strategic USD $8–10 million partnership with a publicly traded biotechnology company focused on the discovery and development of antibody-drug conjugates and bispecific antibodies for potential oncology therapeutics.
- Realigned internal R&D strategy to focus on launching an AI-powered therapeutic pipeline, reinforcing IPA’s shift toward a bio-native AI drug discovery model.
-
ImmunoPrecise subsidiary signed material transfer agreement with Biotheus (now
BioNTech ), for the transfer and evaluation of antibody assets for bispecific tumor-targeting. - Successfully engineered antibodies in silico to a challenging tumor target using LENSai, advancing IPA's vision for accessible, next-generation therapeutics.
-
Appointed industry veteran
Jon Lieber to its Board of Directors, bringing over 30 years of strategic leadership across biotech, capital markets, and public company governance, further strengthening IPA’s financial oversight and commercial execution. -
Named
Jeff Fried , a recognized healthcare data visionary, to itsAdvisory Board . Fried has played a key role in advancing IPA’s AI platform capabilities, particularly the integration of vector search to support large-scale, AI-driven discovery within LENSai ecosystem. - Regained compliance with Nasdaq minimum bid price requirement, reflecting strengthened investor confidence and continued alignment with strategic listing standards.
“Fiscal 2025 was a record-setting year for IPA across multiple dimensions,” said Dr.
“As we look ahead to the next fiscal year, we are well-positioned to build on our momentum. We are poised to refocus our business on AI-based product development utilizing our LENSai platform, powered by our patented HYFT technology. We anticipate the near-term completion of the previously announced divestiture of our Dutch subsidiary, as part of our continued focus on streamlining operations and aligning resources with strategic priorities. Together, these strategic steps will sharpen our focus, strengthen our core capabilities, and set the stage for an even brighter future for IPA,” concluded
Fourth Quarter 2025 Financial Results
Revenue for the three months ended
Gross profit for the three months ended
Research and development (“R&D”) expenses totaled
Sales and marketing expenses increased to
General and administrative expenses declined to
Operating loss, excluding amortization and non-recurring charges, improved significantly to
Net loss narrowed to
Adjusted EBITDA loss improved to
Full Year 2025 Financial Results
Revenue for Fiscal Year 2025 was
Gross Profit for Fiscal Year 2025 was
Research and development expenses were
Sales and marketing expenses were
General and administrative expenses totaled
Operating loss in Fiscal Year 2025, excluding amortization and non-recurring charges, improved to
Net loss in Fiscal Year 2025 was
Total cash, cash equivalents, and marketable securities, including restricted cash, were
The reconciliation of Net Loss to Adjusted EBITDA is presented in the table below:
|
|
Three Months Ended
|
|
|
Year Ended
|
|
||||||||||
(in thousands) |
|
2025
|
|
|
2024
|
|
|
2025
|
|
|
2024
|
|
||||
Net loss |
|
|
(2,161 |
) |
|
|
(17,610 |
) |
|
|
(30,234 |
) |
|
|
(26,115 |
) |
Income taxes |
|
|
261 |
|
|
|
(1,214 |
) |
|
|
(4,033 |
) |
|
|
(2,588 |
) |
Amortization and depreciation |
|
|
913 |
|
|
|
1,579 |
|
|
|
5,119 |
|
|
|
5,735 |
|
Accretion |
|
|
2 |
|
|
|
4 |
|
|
|
10 |
|
|
|
19 |
|
Asset impairment charge |
|
|
— |
|
|
|
15,031 |
|
|
|
21,184 |
|
|
|
15,031 |
|
Foreign exchange realized gain (loss) |
|
|
(33 |
) |
|
|
18 |
|
|
|
(5 |
) |
|
|
142 |
|
Interest expense |
|
|
209 |
|
|
|
323 |
|
|
|
948 |
|
|
|
849 |
|
Interest and other income |
|
|
(3 |
) |
|
|
3 |
|
|
|
283 |
|
|
|
(23 |
) |
Unrealized foreign exchange loss (gain) |
|
|
443 |
|
|
|
(65 |
) |
|
|
594 |
|
|
|
(86 |
) |
Share-based expense |
|
|
53 |
|
|
|
237 |
|
|
|
445 |
|
|
|
1,535 |
|
Adjusted EBITDA |
|
|
(316 |
) |
|
|
(1,694 |
) |
|
|
(5,689 |
) |
|
|
(5,501 |
) |
*All financial figures are in Canadian Dollars (CAD) unless otherwise stated.
Conference Call and Webcast Details
The Company will host a live conference call and webcast to discuss these results and provide a corporate update on
The conference call will be webcast live and available for replay via a link provided in the Events section of the Company’s IR pages at https://ir.ipatherapeutics.com/events-and-presentations/default.aspx.
***Participant Dial-In Details***
Participants call one of the allocated dial-in numbers (below) and advise the Operator of either the Conference ID 3224490 or Conference Name.
***Webcast Details***
Attendee URL:
https://events.q4inc.com/attendee/849565157
Please call the conference telephone number five minutes prior to the start time. An operator will register your name and organization.
Anyone listening to the call is encouraged to read the company's periodic reports available on the company’s profile at www.sedarplus.com and www.sec.gov, including the discussion of risk factors and historical results of operations and financial condition in those reports.
About
For more information, visit www.ipatherapeutics.com
Forward-Looking Statements
This press release contains forward-looking statements within the meaning of applicable
Forward-looking statements in this release include, but are not limited to, statements related to the Company’s operational and financial outlook, the potential impact and continuity of strategic partnerships, including the recently announced commercial agreement and collaborations with cloud infrastructure providers, our projected growth in AI-driven revenues and margins, our ability to commercialize new technologies such as de novo antibody design and AI-designed GLP-1 therapeutics, future demand for our platform capabilities, ongoing strategic initiatives including business realignment and divestitures, and our ability to drive sustainable profitability.
The Company uses certain non-IFRS financial measures as supplemental indicators of its financial and operating performance. These non-IFRS financial measures are adjusted EBITDA and adjusted operating expenses. The Company believes these supplementary financial measures reflect the Company’s ongoing business in a manner that allows for meaningful period-to-period comparisons and analysis of trends in its business. These non-IFRS measures do not have any standardized meaning prescribed under IFRS and are therefore unlikely to be comparable to similar measures presented by other companies.
The Company defines adjusted EBITDA as operating earnings before taxes, amortization, depreciation, accretion, asset impairment charges, foreign exchange gain/loss, interest and other income and share-based compensation. Adjusted EBITDA is presented on a basis consistent with the Company’s internal management reports. The Company discloses adjusted EBITDA to capture the profitability of its business before the impact of items not considered in management’s evaluation of operating unit performance. The most directly comparable IFRS measure to adjusted EBITDA is net loss.
These statements are based on management’s current expectations and assumptions and involve known and unknown risks, uncertainties, and other factors that may cause actual results, performance, or achievements to differ materially from those expressed or implied. These include, but are not limited to: execution risks related to strategic partnerships, delays or failures in technology development or commercialization, market adoption of AI-based drug discovery tools, fluctuations in financial markets, general economic conditions, and risks related to funding requirements and liquidity.
The Company cautions readers not to place undue reliance on these forward-looking statements. All such statements are made as of the date of this release and, unless required by law, the Company assumes no obligation to update or revise them to reflect new events or circumstances.
For a complete discussion of risk factors, investors should refer to IPA’s filings with Canadian and
CONSOLIDATED STATEMENTS OF COMPREHENSIVE LOSS (Unaudited - Expressed in Canadian dollars) |
||||||||||||||||
|
|
Three months ended
|
|
|
Twelve months ended
|
|
||||||||||
(in thousands, except share data) |
|
2025
|
|
|
2024
|
|
|
2025
|
|
|
2024
|
|
||||
REVENUE |
|
|
6,981 |
|
|
|
6,459 |
|
|
|
24,520 |
|
|
|
24,518 |
|
COST OF SALES |
|
|
2,521 |
|
|
|
3,351 |
|
|
|
10,972 |
|
|
|
12,465 |
|
GROSS PROFIT |
|
|
4,460 |
|
|
|
3,108 |
|
|
|
13,548 |
|
|
|
12,053 |
|
EXPENSES |
|
|
|
|
|
|
|
|
|
|
|
|
||||
Research and development |
|
|
1,089 |
|
|
|
1,260 |
|
|
|
4,943 |
|
|
|
4,043 |
|
Sales and marketing |
|
|
1,033 |
|
|
|
910 |
|
|
|
4,298 |
|
|
|
3,543 |
|
General and administrative |
|
|
3,706 |
|
|
|
4,119 |
|
|
|
14,735 |
|
|
|
15,592 |
|
Impairment of |
|
|
— |
|
|
|
11,161 |
|
|
|
— |
|
|
|
11,161 |
|
Impairment of Intangible assets |
|
|
— |
|
|
|
3,870 |
|
|
|
21,184 |
|
|
|
3,870 |
|
Amortization of Intangible assets |
|
|
106 |
|
|
|
701 |
|
|
|
1,948 |
|
|
|
2,968 |
|
|
|
|
5,934 |
|
|
|
22,021 |
|
|
|
47,108 |
|
|
|
41,177 |
|
Loss before other income (expenses) and income taxes |
|
|
(1,474 |
) |
|
|
(18,913 |
) |
|
|
(33,560 |
) |
|
|
(29,124 |
) |
OTHER INCOME (EXPENSES) |
|
|
|
|
|
|
|
|
|
|
|
|
||||
Accretion |
|
|
(2 |
) |
|
|
(4 |
) |
|
|
(10 |
) |
|
|
(19 |
) |
Grant and subsidy income |
|
|
16 |
|
|
|
31 |
|
|
|
180 |
|
|
|
331 |
|
Interest and other (expense) income |
|
|
3 |
|
|
|
(3 |
) |
|
|
(283 |
) |
|
|
23 |
|
Unrealized foreign exchange (loss) gain |
|
|
(443 |
) |
|
|
65 |
|
|
|
(594 |
) |
|
|
86 |
|
|
|
|
(426 |
) |
|
|
89 |
|
|
|
(707 |
) |
|
|
421 |
|
Loss before income taxes |
|
|
(1,900 |
) |
|
|
(18,824 |
) |
|
|
(34,267 |
) |
|
|
(28,703 |
) |
Income taxes |
|
|
(261 |
) |
|
|
1,214 |
|
|
|
4,033 |
|
|
|
2,588 |
|
NET LOSS FOR THE PERIOD |
|
|
(2,161 |
) |
|
|
(17,610 |
) |
|
|
(30,234 |
) |
|
|
(26,115 |
) |
OTHER COMPREHENSIVE INCOME (LOSS) |
|
|||||||||||||||
Items that will be reclassified subsequently to loss |
|
|||||||||||||||
Exchange difference on translating foreign operations |
|
|
593 |
|
|
|
497 |
|
|
|
1,139 |
|
|
|
(613 |
) |
COMPREHENSIVE LOSS FOR THE PERIOD |
|
|
(1,568 |
) |
|
|
(17,113 |
) |
|
|
(29,095 |
) |
|
|
(26,728 |
) |
LOSS PER SHARE – BASIC AND DILUTED |
|
|
(0.05 |
) |
|
|
(0.66 |
) |
|
|
(0.91 |
) |
|
|
(1.02 |
) |
WEIGHTED AVERAGE NUMBER OF SHARES OUTSTANDING |
|
|
45,800,482 |
|
|
|
26,668,766 |
|
|
|
33,385,499 |
|
|
|
25,635,526 |
|
CONSOLIDATED STATEMENTS OF FINANCIAL POSITION (Unaudited - Expressed in Canadian dollars) |
||||||||
(in thousands) |
|
|
|
|
|
|
||
ASSETS |
|
|
|
|
|
|
||
Current assets |
|
|
|
|
|
|
||
Cash |
|
|
10,665 |
|
|
|
3,459 |
|
Amounts receivable, net |
|
|
4,115 |
|
|
|
3,790 |
|
Tax receivable |
|
|
143 |
|
|
|
414 |
|
Inventory |
|
|
2,095 |
|
|
|
2,139 |
|
Unbilled revenue |
|
|
548 |
|
|
|
277 |
|
Prepaid expenses |
|
|
1,188 |
|
|
|
1,408 |
|
|
|
|
18,754 |
|
|
|
11,487 |
|
Restricted cash |
|
|
126 |
|
|
|
86 |
|
Deposit on equipment |
|
|
502 |
|
|
|
475 |
|
Property and equipment |
|
|
15,762 |
|
|
|
16,696 |
|
Intangible assets |
|
|
1,067 |
|
|
|
23,557 |
|
|
|
|
8,230 |
|
|
|
7,687 |
|
Total assets |
|
|
44,441 |
|
|
|
59,988 |
|
LIABILITIES |
|
|
|
|
|
|
||
Current liabilities |
|
|
|
|
|
|
||
Accounts payable and accrued liabilities |
|
|
5,283 |
|
|
|
4,372 |
|
Deferred revenue |
|
|
1,090 |
|
|
|
1,352 |
|
Tax payable |
|
|
475 |
|
|
|
553 |
|
Leases |
|
|
1,850 |
|
|
|
1,563 |
|
Deferred acquisition payments |
|
|
314 |
|
|
|
284 |
|
|
|
|
9,012 |
|
|
|
8,124 |
|
Leases |
|
|
11,553 |
|
|
|
12,118 |
|
Deferred income tax liability |
|
|
250 |
|
|
|
4,068 |
|
Total liabilities |
|
|
20,815 |
|
|
|
24,310 |
|
SHAREHOLDERS' EQUITY |
|
|
|
|
|
|
||
Share capital |
|
|
136,371 |
|
|
|
119,773 |
|
Contributed surplus |
|
|
12,833 |
|
|
|
12,388 |
|
Accumulated other comprehensive income |
|
|
3,216 |
|
|
|
2,077 |
|
Accumulated deficit |
|
|
(128,794 |
) |
|
|
(98,560 |
) |
|
|
|
23,626 |
|
|
|
35,678 |
|
Total liabilities and shareholders’ equity |
|
|
44,441 |
|
|
|
59,988 |
|
CONSOLIDATED STATEMENTS OF CASH FLOWS
For the year ended (Unaudited - Expressed in Canadian dollars) |
||||||||
(in thousands) |
|
2025
|
|
|
2024
|
|
||
Operating activities: |
|
|
|
|
|
|
||
Net loss for the period |
|
|
(30,234 |
) |
|
|
(26,115 |
) |
Items not affecting cash: |
|
|
|
|
|
|
||
Accretion |
|
|
10 |
|
|
|
19 |
|
Amortization and depreciation |
|
|
5,119 |
|
|
|
5,735 |
|
Asset impairment |
|
|
21,184 |
|
|
|
15,031 |
|
Deferred income taxes |
|
|
(3,935 |
) |
|
|
(1,773 |
) |
Foreign exchange |
|
|
622 |
|
|
|
15 |
|
Gain on investment |
|
|
(7 |
) |
|
|
(2 |
) |
Share-based expense |
|
|
445 |
|
|
|
1,535 |
|
|
|
|
(6,796 |
) |
|
|
(5,555 |
) |
Changes in non-cash working capital related to operations: |
|
|
|
|
|
|
||
Amounts receivable |
|
|
(298 |
) |
|
|
(601 |
) |
Inventory |
|
|
138 |
|
|
|
(102 |
) |
Unbilled revenue |
|
|
(248 |
) |
|
|
360 |
|
Prepaid expenses |
|
|
261 |
|
|
|
624 |
|
Accounts payable and accrued liabilities |
|
|
827 |
|
|
|
983 |
|
Sales and income taxes payable and receivable |
|
|
8 |
|
|
|
733 |
|
Deferred revenue |
|
|
(302 |
) |
|
|
374 |
|
Net cash used in operating activities |
|
|
(6,410 |
) |
|
|
(3,184 |
) |
Investing activities: |
|
|
|
|
|
|
||
Purchase of equipment |
|
|
(799 |
) |
|
|
(1,397 |
) |
Security deposit on leases |
|
|
— |
|
|
|
(141 |
) |
Deferred acquisition payments |
|
|
— |
|
|
|
(146 |
) |
Sale of |
|
|
— |
|
|
|
121 |
|
Net cash used in investing activities |
|
|
(799 |
) |
|
|
(1,563 |
) |
Financing activities: |
|
|
|
|
|
|
||
Proceeds from share issuance, net of transaction costs |
|
|
12,228 |
|
|
|
2,360 |
|
Proceeds from debenture |
|
|
4,242 |
|
|
|
— |
|
Repayment of leases |
|
|
(1,577 |
) |
|
|
(1,339 |
) |
Net cash provided by financing activities |
|
|
14,893 |
|
|
|
1,021 |
|
Increase (decrease) in cash during the period |
|
|
7,684 |
|
|
|
(3,726 |
) |
Foreign exchange |
|
|
(438 |
) |
|
|
(1,095 |
) |
Cash – beginning of the period |
|
|
3,545 |
|
|
|
8,366 |
|
Cash – end of the period |
|
|
10,791 |
|
|
|
3,545 |
|
Cash is comprised of: |
|
|
|
|
|
|
||
Cash |
|
|
10,665 |
|
|
|
3,459 |
|
Restricted cash |
|
|
126 |
|
|
|
86 |
|
|
|
|
10,791 |
|
|
|
3,545 |
|
Cash paid for interest |
|
|
— |
|
|
|
— |
|
Cash paid for income tax |
|
|
2 |
|
|
|
— |
|
View source version on businesswire.com: https://www.businesswire.com/news/home/20250729317438/en/
Investor Relations Contact
investors@ipatherapeutics.com
Source: