Waters Introduces Next-Generation Microflow LC Columns with MaxPeak Premier Technology, Delivering Higher Sensitivity with Lower Sample and Solvent Usage
Headlines:
- Delivers up to 2× higher sensitivity than stainless steel microflow columns, lowering detection and quantitation limits across high-throughput bioseparations, DMPK, and 'omics applications.1
- Uses up to 75% less sample than 2.1 mm I.D. columns, conserving precious materials such as cell and gene therapy and personalized medicine candidates while delivering deeper insights. 2
- Reduces solvent consumption by up to 4× versus 2.1 mm I.D. columns, helping laboratories meet sustainability goals, lower operating costs, and accelerate time to results without compromising performance. 2
This launch builds on the Company's strong cadence of high-impact chemistry innovation, redefining what is possible in the separation of larger, more complex molecules by exceeding the limits of current technologies.
"Waters continues to invest in the advancement of breakthrough technologies to remove common obstacles for our customers in high-throughput pharmaceutical and biopharmaceutical laboratories, accelerating and simplifying the development of life-changing therapies," said
The new microflow LC columns apply Waters' MaxPeak High Performance Surface (HPS) Technology to a 1 mm I.D. format. This significant advancement minimizes nonspecific adsorption (NSA) and improves recovery for small molecules, peptides, and oligonucleotides. MaxPeak HPS Technology is of particular benefit for those investigating molecules with challenging analyte recovery, such as phosphorylated peptides, by removing analytical barriers and speeding workflows.
"We saw a strong benefit matching, or even exceeding, our analytical sensitivity requirements when switching from 2.1 mm I.D. stainless steel columns to Waters' MaxPeak Premier Technology columns. It's great to have MaxPeak Technology now available in 1 mm I.D. microflow columns. They'll give our metabolomics team the opportunity to save solvent while delivering reproducible, fast, and highly accurate results in high-throughput operations," said
Using these columns, scientists can consistently expect sharper peaks, enhanced peak capacity, and reduced peak tailing even at low flow rates, along with highly reproducible performance from the very first injection. These benefits significantly reduce the time and variability associated with column passivation in traditional stainless steel column designs. For customers transitioning from 2.1 mm I.D. analytical-scale LC columns to microflow formats, the new 1 mm I.D. columns deliver equivalent or improved sensitivity, while using only one-quarter of the solvent and sample required for analytical flow, helping labs meet their environmental goals while improving analytical performance.
The new 1 mm I.D. columns with Waters' MaxPeak Premier Technology will be available globally beginning
Additional Resources: Microflow Columns with MaxPeak Premier Technology
Waters, MaxPeak,
ABOUT:
References:
1. Application note: "Enhanced Recovery and Peak Shape of Acidic Peptides with BioResolve™ 1 mm I.D. Columns with MaxPeak™ Premier Technology"
2. Application note: "Improving Sensitivity and Analytical Method Greenness using MaxPeak™ Premier 1.0 mm I.D. Columns"
Contact:
Head of
Waters Corporation
508.498.9732
molly_gluck@waters.com
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