Canada and CSL Seqirus, a Global Leader in Influenza Vaccines, agree on new Pandemic Preparedness Contract
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CSL Seqirus will supply millions of doses of adjuvanted cell-based vaccine to support Canadians, in the event the
World Health Organization (WHO ) declares an influenza pandemic. - The continued detection of influenza viruses of pandemic potential, including highly pathogenic avian influenza infecting wild birds, poultry and mammals, underscores the pandemic threat posed by influenza and the potential public health risk .1
Under the terms of the agreement, CSL Seqirus has committed to rapidly manufacture and deliver millions of doses of cell-based adjuvanted influenza vaccines to help protect Canadians if an influenza pandemic is declared by the
Under a previous agreement with PHAC, CSL Seqirus was contracted to provide an egg-based influenza vaccine in the event of a pandemic. This shift towards cell-based vaccines builds on the successful introduction of cell-based Flucelvax® , Influenza Vaccine (surface antigen, inactivated, prepared in cell cultures), into
"This new contract with CSL Seqirus strengthens
Cell-based manufacturing provides a proven technology platform for pandemic influenza vaccines. These benefits include scalability, reduced reliance on large volumes of critical materials, and the ability to rapidly produce vaccines using state-of-the-art technology. The introduction of this technology into
"The health and safety of Canadians always comes first", says the Honourable Joel Lightbound, Minister of Government Transformation, Public Works and Procurement. "This new contract ensures
As cases of avian influenza viruses of pandemic potential continue to be detected worldwide, there is critical importance in maintaining robust pandemic preparedness capabilities and strategic partnerships between governments and industry leaders in vaccine development.
About Pandemic Influenza
Influenza is a contagious airborne respiratory disease.3,4 The risk of influenza-associated morbidity and mortality is greater with pandemic influenza than with seasonal influenza because there is likely to be little or no pre-existing immunity to the novel virus in the human population.5 The timing and severity of pandemic influenza is unpredictable. Four influenza pandemics have occurred since 1918, with the 1918 pandemic being the most severe in recent history, with an estimated mortality of up to 50 million people worldwide.6
About Avian Influenza
Avian influenza spreads predominantly among birds.7 Avian influenza viruses do not normally infect humans however humans have been infected with avian influenza viruses in rare cases.8 Illness in humans from avian influenza has varied in levels of severity from no symptoms or mild illness to severe disease and death.7 The spread of avian influenza from one human to another is very rare and typically has only spread to a few people.7
For information on the persistent levels of highly pathogenic avian influenza seen in recent years, CSL Seqirus recommends referring to the
About CSL Seqirus
CSL Seqirus is part of CSL (ASX: CSL). As a global leader in the protection of public health and one of the largest influenza vaccine providers in the world, CSL Seqirus is committed to preventing infectious diseases, like influenza and COVID-19, and is a transcontinental partner in pandemic preparedness. With state-of-the-art production facilities in the US, the
For more information about CSL Seqirus, visit www.CSL.com.
About CSL
CSL (ASX:CSL) (USOTC:CSLLY) is a global biotechnology company with a dynamic portfolio of medicines, including those that treat hemophilia and immune deficiencies, vaccines to prevent influenza, and therapies in iron deficiency and nephrology. Since our start in 1916, we have been driven by our promise to save lives using the latest technologies. Today, CSL – including our three businesses:
Intended Audience
This press release is issued from CSL Seqirus in
Forward-Looking Statements
This press release may contain forward-looking statements, including statements regarding future results, performance or achievements. These statements involve known and unknown risks, uncertainties and other factors which may cause our actual results, performance or achievements to be materially different from any future results, performances or achievements expressed or implied by the forward-looking statements. These statements reflect our current views with respect to future events and are based on assumptions and subject to risks and uncertainties. Given these uncertainties, you should not place undue reliance on these forward-looking statements.
FLUCELVAX® Influenza Vaccine (surface antigen, inactivated, prepared in cell cultures)
PATIENT MEDICATION INFORMATION
What is FLUCELVAX® (Influenza Vaccine)?
FLUCELVAX® is a vaccine that helps protect people aged 6 months and older from the flu. Vaccination with FLUCELVAX® may not protect all people
You should not receive FLUCELVAX® if you have a history of severe allergic reactions (e.g., anaphylaxis) to any component of the vaccine.
Before receiving FLUCELVAX®, tell your healthcare provider about all medical conditions, including if you:
- have ever had Guillain-Barré syndrome (severe muscle weakness) within six weeks after getting a flu vaccine. The decision to give FLUCELVAX® should be made by your healthcare provider, based on careful consideration of the potential benefits and risks.
- have problems with your immune system or are taking certain medications that suppress your immune system, as these may reduce your immune response to the vaccine
- have ever fainted when receiving a vaccine
What are the most common side effects of FLUCELVAX®?
- pain and/or redness where the vaccine was given
- headache
- extreme tiredness
- muscle aches
Additional side effects seen in children include:
- tenderness, bruising and/or a raised hardened area where the vaccine was given
- sleepiness
- irritability
- diarrhea
- changes in eating habits
- feeling unwell (malaise)
These are not all of the possible side effects of FLUCELVAX®.
You can ask your healthcare provider for more information and for advice about any side effects that concern you.
What do I do if I have side effects?
Report any severe or unusual side effects to your healthcare provider.
To report SUSPECTED ADVERSE REACTIONS, contact CSL Seqirus at 1-855-358-8966 (Please select option 1 when prompted) or email: ae.reporting@seqirus.com
Before receiving this vaccine, please see the full prescribing Information for FLUCELVAX ®. You can ask your healthcare provider or pharmacist for information about FLUCELVAX® that is written for healthcare professionals.
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1 EFSA Journal Avian influenza overview. Available at: https://efsa.onlinelibrary.wiley.com/doi/epdf/10.2903/j.efsa.2025.9352 [Accessed |
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SOURCE CSL Seqirus