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About the company
Dyne Therapeutics, Inc. is a clinical-stage neuromuscular disease company. It is discovering and advancing therapeutics for people living with genetically driven neuromuscular diseases. Leveraging the modularity of its FORCE platform, it is developing targeted therapeutics that deliver to muscle and the central nervous system (CNS). It has a broad pipeline for neuromuscular diseases, including clinical programs for myotonic dystrophy type 1 (DM1) and Duchenne muscular dystrophy (DMD) and preclinical programs for facioscapulohumeral muscular dystrophy (FSHD) and Pompe disease. Its product candidate, DYNE-101, is being evaluated in ACHIEVE, an ongoing Phase I/II global clinical trial in patients with DM1. Its product candidate, DYNE-251, is being evaluated in DELIVER, an ongoing Phase I/II global clinical trial in patients with DMD who have mutations amenable to exon 51 skipping. Its other product candidates are DYNE-302 and DYNE-401. DYNE-302 addresses the genetic basis of FSHD.
- Revenue in USD (TTM)0.00
- Net income in USD-423.80m
- Incorporated2013
- Employees240.00
- LocationDyne Therapeutics Inc1560 Trapelo RoadWALTHAM 02451United StatesUSA
- Phone+1 (781) 786-8230
- Fax+1 (781) 786-8866
- Websitehttps://dyne-tx.com/
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Peer analysis
Key Information
- Key Information
- Stock Performance
- Per Share Data
- Efficiency
- Management Effectiveness
- Profitability
- Financial Strength
- Growth Rates
| Company | Revenue (TTM) | Net income (TTM) | Market cap | Employees | Price/earnings (TTM) | Price/book value (MRQ) | Price/cash flow (TTM) | Price/sales (TTM) | EPS (excl. extraordinary items, TTM) | EPS (incl. extraordinary items, TTM) | Revenue per share (TTM) | Book value per share (MRQ) | Asset turnover (TTM) | Inventory turnover (TTM) | Receivables turnover (TTM) | Revenues per employee (TTM) | Return on avg assets (TTM) | Return on avg assets (5 yr avg) | Return on investment (TTM) | Return on investment (5 yr avg) | Gross margin (TTM) | Gross margin (5 yr avg) | Net profit margin (TTM) | Net Profit margin (5 yr avg) | Quick ratio (MRQ) | Interest coverage (TTM) | Total debt to capital (MRQ) | Payout ratio (5 yr avg) | Revenue (YOY change %) | Revenue (5 yr growth rate) | Net income (YOY change %) | Net income (5 yr growth rate) | Capital expenditure (5 yr growth rate) | Dividend (5 yr growth rate) |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| BioCryst Pharmaceuticals Inc | 874.84m | 263.86m | 2.16bn | 435.00 | 7.17 | -- | 8.11 | 2.47 | 1.20 | 1.20 | 4.00 | -0.5593 | 1.74 | 2.83 | 9.41 | 2,011,120.00 | 52.53 | -18.78 | 81.42 | -25.41 | 97.82 | 97.60 | 30.16 | -23.15 | 2.03 | 4.99 | 1.34 | -- | 94.10 | 117.89 | 396.87 | -- | 36.86 | -- |
| Maze Therapeutics Inc | 0.00 | -101.46m | 2.19bn | 125.00 | -- | 5.78 | -- | -- | -2.68 | -2.68 | 0.00 | 7.89 | 0.00 | -- | -- | 0.00 | -41.05 | -- | -43.88 | -- | -- | -- | -- | -- | -- | -- | 0.00 | -- | -- | -- | 103.39 | -- | -- | -- |
| Mineralys Therapeutics Inc | 0.00 | -171.36m | 2.32bn | 51.00 | -- | 4.02 | -- | -- | -2.96 | -2.96 | 0.00 | 7.30 | 0.00 | -- | -- | 0.00 | -39.48 | -- | -42.14 | -- | -- | -- | -- | -- | -- | -- | 0.00 | -- | -- | -- | -147.31 | -- | -- | -- |
| Dianthus Therapeutics Inc | 3.08m | -126.35m | 2.37bn | 78.00 | -- | 4.33 | -- | 769.76 | -3.48 | -3.48 | 0.085 | 12.75 | 0.0066 | -- | 0.8013 | 39,461.54 | -27.12 | -37.13 | -28.32 | -39.78 | -- | -- | -4,104.78 | -3,874.39 | -- | -- | 0.00 | -- | 120.63 | -- | -95.08 | -- | -49.06 | -- |
| Immunome Inc | 9.68m | -222.74m | 2.45bn | 118.00 | -- | 7.72 | -- | 253.17 | -2.95 | -2.95 | 0.122 | 2.88 | 0.0348 | -- | -- | 82,025.42 | -80.08 | -120.50 | -91.80 | -146.20 | -- | -- | -2,301.30 | -2,078.20 | -- | -- | 0.00 | -- | -35.50 | -- | -174.29 | -- | 196.63 | -- |
| Adaptive Biotechnologies Corp | 276.98m | -59.50m | 2.48bn | 624.00 | -- | 11.33 | -- | 8.96 | -0.3987 | -0.3987 | 1.79 | 1.42 | 0.5265 | 7.82 | 6.01 | 443,871.80 | -11.30 | -22.45 | -13.86 | -25.94 | 74.24 | 66.23 | -21.47 | -88.21 | 3.23 | -24.47 | 0.3684 | -- | 54.77 | 23.00 | 62.69 | -- | -30.92 | -- |
| Disc Medicine Inc | 0.00 | -212.18m | 2.54bn | 155.00 | -- | 3.41 | -- | -- | -5.98 | -5.98 | 0.00 | 19.53 | 0.00 | -- | -- | 0.00 | -32.55 | -30.94 | -34.12 | -32.93 | -- | -- | -- | -- | -- | -- | 0.0379 | -- | -- | -- | -94.03 | -- | -- | -- |
| Wave Life Sciences Ltd | 42.73m | -204.38m | 2.61bn | 317.00 | -- | 5.01 | -- | 61.02 | -1.21 | -1.21 | 0.2534 | 2.80 | 0.0863 | -- | 31.67 | 134,785.50 | -41.26 | -44.67 | -52.09 | -71.58 | -- | -- | -478.33 | -208.12 | -- | -- | 0.00 | -- | -60.55 | 16.31 | -110.68 | -- | -11.71 | -- |
| Dyne Therapeutics Inc | 0.00 | -423.80m | 2.61bn | 240.00 | -- | 3.33 | -- | -- | -3.66 | -3.66 | 0.00 | 4.85 | 0.00 | -- | -- | 0.00 | -51.81 | -57.98 | -55.30 | -63.58 | -- | -- | -- | -- | -- | -- | 0.1254 | -- | -- | -- | -34.54 | -- | 7.60 | -- |
| Travere Therapeutics Inc | 490.73m | -50.26m | 2.72bn | 497.00 | -- | 23.38 | 259.86 | 5.55 | -0.603 | -0.3293 | 5.30 | 1.26 | 0.8184 | 1.71 | 9.15 | 987,382.30 | -8.38 | -37.69 | -11.99 | -48.59 | 97.89 | 96.60 | -10.24 | -116.71 | 2.70 | -- | 0.7308 | -- | 110.45 | 19.87 | 84.32 | -- | 18.81 | -- |
| Veracyte Inc | 517.15m | 66.35m | 2.86bn | 755.00 | 44.20 | 2.18 | 32.60 | 5.53 | 0.8147 | 0.8147 | 6.45 | 16.50 | 0.3822 | 7.31 | 11.34 | 684,960.30 | 4.90 | -1.69 | 5.17 | -1.78 | 70.10 | 67.87 | 12.83 | -5.22 | 7.81 | -- | 0.00 | -- | 16.01 | 34.50 | 174.89 | -- | 27.81 | -- |
| Vera Therapeutics Inc | 0.00 | -299.62m | 2.88bn | 249.00 | -- | 4.77 | -- | -- | -4.66 | -4.66 | 0.00 | 8.48 | 0.00 | -- | -- | 0.00 | -43.10 | -46.45 | -45.69 | -50.25 | -- | -- | -- | -- | -- | -- | 0.1102 | -- | -- | -- | -96.92 | -- | 44.79 | -- |
| Ideaya Biosciences Inc | 218.71m | -113.70m | 2.90bn | 145.00 | -- | 2.84 | -- | 13.27 | -1.30 | -1.30 | 2.46 | 11.65 | 0.1959 | -- | 73.20 | 1,508,345.00 | -10.18 | -18.78 | -10.68 | -20.00 | -- | -- | -51.99 | -185.86 | -- | -- | 0.00 | -- | 3,024.43 | 62.11 | 58.58 | -- | 36.87 | -- |
| Beam Therapeutics Inc | 139.74m | -79.99m | 2.92bn | 511.00 | -- | 2.36 | -- | 20.91 | -0.9703 | -0.9703 | 1.41 | 12.17 | 0.1081 | -- | -- | 273,469.70 | -6.19 | -19.28 | -6.94 | -22.57 | -- | -- | -57.24 | -176.36 | -- | -- | 0.00 | -- | 120.01 | 466.27 | 78.77 | -- | -1.79 | -- |
| Arcus Biosciences Inc | 247.00m | -353.00m | 3.00bn | 601.00 | -- | 4.75 | -- | 12.15 | -3.30 | -3.30 | 2.30 | 5.04 | 0.2158 | -- | 12.05 | 410,981.70 | -30.84 | -18.85 | -38.54 | -22.29 | -- | -- | -142.92 | -103.61 | -- | -- | 0.1356 | -- | -4.26 | 26.08 | -24.73 | -- | -8.12 | -- |
Data as of Mar 02 2026. Currency figures normalised to Dyne Therapeutics Inc's reporting currency: US Dollar USD
50.30%Per cent of shares held by top holders
| Holder | Shares | % Held |
|---|---|---|
| T. Rowe Price Investment Management, Inc.as of 31 Dec 2025 | 17.54m | 10.84% |
| Janus Henderson Investors US LLCas of 31 Dec 2025 | 13.79m | 8.53% |
| The Vanguard Group, Inc.as of 31 Dec 2025 | 10.13m | 6.26% |
| BlackRock Fund Advisorsas of 31 Dec 2025 | 9.48m | 5.86% |
| SSgA Funds Management, Inc.as of 31 Dec 2025 | 6.69m | 4.14% |
| Fidelity Management & Research Co. LLCas of 31 Dec 2025 | 6.57m | 4.06% |
| Adage Capital Management LPas of 31 Dec 2025 | 5.17m | 3.20% |
| Orbis Investment Management Ltd.as of 31 Dec 2025 | 4.80m | 2.97% |
| Perceptive Advisors LLCas of 31 Dec 2025 | 3.48m | 2.45% |
| Geode Capital Management LLCas of 31 Dec 2025 | 3.26m | 2.02% |
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Data from 31 Dec 2025 - 31 Dec 2025Source: FactSet Research Systems Inc.
