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Structure Therapeutics Inc

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GPCR:NMQ

Structure Therapeutics Inc

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Health CarePharmaceuticals and Biotechnology
  • Price (USD)64.15
  • Today's Change1.25 / 1.98%
  • Shares traded673.65k
  • 1 Year change+187.13%
  • Beta--
Data delayed at least 15 minutes, as of Mar 03 2026 18:30 GMT.
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About the company

Structure Therapeutics Inc. is a clinical-stage biopharmaceutical company focused on discovering and developing oral small molecule treatments for chronic metabolic and cardiopulmonary conditions with significant unmet medical needs. Its programs include Aleniglipron (GSBR-1290), ACCG-2671, GIP and GCG Receptor Oral Small Molecule Obesity Programs, ANPA-0073, and LTSE-2578. Its Aleniglipron is an oral and biased small molecule agonist of GLP-1R, a validated GPCR drug target for obesity. ACCG-2671 is an oral small molecule amylin receptor agonist for obesity. ANPA-0073 is a biased agonist targeting the apelin (APJ) receptor agonist. Its LTSE-2578, an Oral Small Molecule LPA1R Antagonist for IPF. It is developing an antagonist that targets lysophosphatidic acid 1 receptor (LPA1R), a GPCR implicated in responses to tissue injury and pro-fibrotic processes, for the treatment of IPF. It is developing oral incretins for potential combination therapy with GLP-1R or amylin candidates.

  • Revenue in USD (TTM)0.00
  • Net income in USD-141.20m
  • Incorporated2019
  • Employees220.00
  • Location
    Structure Therapeutics Inc601 Gateway Blvd Suite 900SOUTH SAN FRANCISCO 94080United StatesUSA
  • Phone+1 (650) 457-1978
  • Websitehttps://structuretx.com/
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Peer analysis

Key Information
CompanyRevenue (TTM)Net income (TTM)Market capEmployeesPrice/earnings (TTM)Price/book value (MRQ)Price/cash flow (TTM)Price/sales (TTM)EPS (excl. extraordinary items, TTM)EPS (incl. extraordinary items, TTM)Revenue per share (TTM)Book value per share (MRQ)Asset turnover (TTM)Inventory turnover (TTM)Receivables turnover (TTM)Revenues per employee (TTM)Return on avg assets (TTM)Return on avg assets (5 yr avg)Return on investment (TTM)Return on investment (5 yr avg)Gross margin (TTM)Gross margin
(5 yr avg)
Net profit margin (TTM)Net Profit margin
(5 yr avg)
Quick ratio (MRQ)Interest coverage (TTM)Total debt to capital (MRQ)Payout ratio
(5 yr avg)
Revenue
(YOY change %)
Revenue
(5 yr growth rate)
Net income
(YOY change %)
Net income
(5 yr growth rate)
Capital expenditure
(5 yr growth rate)
Dividend
(5 yr growth rate)
Alumis Inc22.12m-245.15m3.70bn233.00--8.06--167.48-3.85-3.850.30573.690.0491--9.28131,672.60-54.44---61.16-------1,108.24------0.00-------89.84------
Viking Therapeutics Inc0.00-359.64m3.85bn53.00--5.99-----3.18-3.180.005.570.00----0.00-44.29-31.71-47.32-33.62------------0.00-------227.05------
ACADIA Pharmaceuticals Inc1.07bn391.00m3.89bn796.0010.003.179.663.632.282.286.317.210.77873.149.731,346,112.0028.423.9237.605.1791.6993.5936.494.593.71--0.000.0011.8719.3972.66--68.65--
Gyroscope Therapeutics Holdings Ltd(ADR)-100.00bn-100.00bn4.02bn167.00-------------------------------------------------70.87---58.56------
Crinetics Pharmaceuticals Inc7.70m-465.32m4.26bn594.00--3.92--553.46-4.94-4.940.081810.380.006--1.7112,956.23-36.34-36.26-38.52-38.4566.07---6,046.22-6,696.8412.30--0.00--640.71155.27-55.93--98.71--
Scholar Rock Holding Corp0.00-353.43m4.44bn196.00--17.60-----3.15-3.150.002.470.00----0.00-119.63-45.06-144.40-51.62-------1,134.62----0.2891-------48.56---49.93--
Structure Therapeutics Inc (ADR)0.00-141.20m4.46bn220.00--2.94-----2.49-2.490.0021.410.00----0.00-11.35-18.40-11.83-19.33------------0.00-------15.24--185.66--
Terns Pharmaceuticals Inc0.00-94.44m4.46bn59.00--12.95-----1.03-1.030.003.250.00----0.00-27.78-32.69-28.92-35.03-------33,013.70----0.00------1.50---45.82--
Erasca Inc0.00-127.69m4.50bn103.00--11.85-----0.4506-0.45060.001.230.00----0.00-26.90-41.53-28.68-44.78------------0.00-------29.28---36.84--
Amicus Therapeutics, Inc.634.21m-27.11m4.51bn511.00--16.28--7.11-0.0885-0.08852.050.88220.73110.41965.861,241,116.00-3.13-17.56-4.02-21.7188.5089.24-4.27-32.861.880.80510.5888--20.0519.4451.68--0.424--
Apogee Therapeutics Inc0.00-253.67m4.84bn196.00--7.17-----4.36-4.360.009.890.00----0.00-36.18---37.98--------------0.00-------116.88------
CG Oncology Inc2.17m-151.48m4.88bn113.00--6.58--2,243.32-2.03-2.030.02928.780.0034--6.6719,238.94-23.63---24.51--4.09---6,967.99--22.74--0.0043--458.33---29.85------
Celcuity Inc0.00-162.72m5.01bn87.00--40.07-----3.67-3.670.002.700.00----0.00-43.45-42.61-47.58-45.75-----------48.300.7325-------75.26---8.05--
Alkermes Plc1.48bn241.66m5.04bn2.05k21.122.7518.473.421.431.438.7410.990.64981.044.08719,950.8010.6410.1113.6813.2286.6984.1016.3715.063.19--0.000.00-5.257.28-35.06---0.8671--
Data as of Mar 03 2026. Currency figures normalised to Structure Therapeutics Inc's reporting currency: US Dollar USD

Institutional shareholders

23.32%Per cent of shares held by top holders
HolderShares% Held
Fidelity Management & Research Co. LLCas of 31 Dec 20257.98m4.62%
Wellington Management Co. LLPas of 31 Dec 20256.75m3.91%
Avoro Capital Advisor LLCas of 31 Dec 20256.56m3.79%
Janus Henderson Investors US LLCas of 31 Dec 20254.95m2.87%
Deep Track Capital LPas of 31 Dec 20254.11m2.38%
BVF Partners LPas of 31 Dec 20253.48m2.01%
Morgan Stanley & Co. LLCas of 31 Dec 20251.73m1.00%
T. Rowe Price Associates, Inc. (IM)as of 31 Dec 20251.67m0.97%
Driehaus Capital Management LLCas of 31 Dec 20251.64m0.95%
Baker Bros. Advisors LPas of 31 Dec 20251.43m0.83%
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Data from 31 Dec 2025 - 31 Dec 2025Source: FactSet Research Systems Inc.
Data Provided by LSEG
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