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About the company
Centessa Pharmaceuticals plc is a clinical-stage pharmaceutical company. The Company's advanced product candidate, SerpinPC, is a subcutaneously administered inhibitor of activated protein C (APC) being developed as a potential treatment for hemophilia. Leveraging its LockBody technology, it is developing an approach to selectively drive potent effector function activity, such as CD47 or CD3, into the tumor microenvironment (TME) while avoiding systemic toxicity. Its first LockBody product candidate, LB101, is a conditionally tetravalent PD-L1xCD47 bispecific monoclonal antibody used in solid tumors. Its other programs consist of earlier-stage preclinical assets, including ORX750, an orally administered, selective Orexin Receptor-2 (OX2R) agonist for the treatment of narcolepsy (NT1) with potential expansion into other sleep disorders, and MGX292, a protein-engineered variant of human bone morphogenetic protein 9 (BMP9) for the treatment of pulmonary arterial hypertension (PAH).
- Revenue in USD (TTM)6.85m
- Net income in USD-151.09m
- Incorporated2020
- Employees76.00
- LocationCentessa Pharmaceuticals PLC3Rd Floor, 1 Ashley RoadALTRINCHAM WA14 2DTUnited KingdomGBR
- Websitehttps://www.centessa.com/
Peer analysis
- Key Information
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- Per Share Data
- Efficiency
- Management Effectiveness
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- Financial Strength
- Growth Rates
Company | Revenue (TTM) | Net income (TTM) | Market cap | Employees | Price/earnings (TTM) | Price/book value (MRQ) | Price/cash flow (TTM) | Price/sales (TTM) | EPS (excl. extraordinary items, TTM) | EPS (incl. extraordinary items, TTM) | Revenue per share (TTM) | Book value per share (MRQ) | Asset turnover (TTM) | Inventory turnover (TTM) | Receivables turnover (TTM) | Revenues per employee (TTM) | Return on avg assets (TTM) | Return on avg assets (5 yr avg) | Return on investment (TTM) | Return on investment (5 yr avg) | Gross margin (TTM) | Gross margin (5 yr avg) | Net profit margin (TTM) | Net Profit margin (5 yr avg) | Quick ratio (MRQ) | Interest coverage (TTM) | Total debt to capital (MRQ) | Payout ratio (5 yr avg) | Revenue (YOY change %) | Revenue (5 yr growth rate) | Net income (YOY change %) | Net income (5 yr growth rate) | Capital expenditure (5 yr growth rate) | Dividend (5 yr growth rate) |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
OPKO Health Inc | 863.49m | -188.86m | 906.09m | 3.93k | -- | 0.7236 | -- | 1.05 | -0.2513 | -0.2513 | 1.15 | 1.80 | 0.4133 | 7.80 | 6.89 | 219,718.60 | -9.03 | -7.14 | -10.03 | -8.14 | 36.84 | 34.42 | -21.86 | -13.83 | 1.22 | -15.24 | 0.1574 | -- | -14.01 | -2.70 | 42.49 | -- | -10.19 | -- |
BioCryst Pharmaceuticals Inc | 331.41m | -226.54m | 918.17m | 536.00 | -- | -- | -- | 2.77 | -1.18 | -1.18 | 1.72 | -2.21 | 0.6212 | 0.1658 | 6.16 | 618,306.00 | -42.46 | -47.95 | -55.84 | -64.89 | 98.59 | 97.06 | -68.36 | -114.94 | 3.12 | -1.11 | 2.19 | -- | 22.37 | 74.21 | 8.33 | -- | 42.73 | -- |
Arcutis Biotherapeutics Inc | 59.61m | -262.14m | 924.20m | 296.00 | -- | 8.73 | -- | 15.51 | -3.90 | -3.90 | 0.8602 | 0.9161 | 0.1508 | 0.483 | 3.48 | 201,371.60 | -66.31 | -65.64 | -74.24 | -71.72 | 91.63 | -- | -439.79 | -1,513.03 | 6.80 | -8.11 | 0.6947 | -- | 1,517.09 | -- | 15.83 | -- | -- | -- |
Relay Therapeutics Inc | 35.33m | -329.12m | 931.64m | 309.00 | -- | 1.25 | -- | 26.37 | -2.64 | -2.64 | 0.2841 | 5.64 | 0.0376 | -- | -- | 109,371.50 | -35.03 | -28.55 | -37.16 | -29.54 | -- | -- | -931.64 | -998.20 | -- | -- | 0.00 | -- | 1,749.82 | -- | -17.72 | -- | 19.59 | -- |
Praxis Precision Medicines Inc | 2.45m | -123.28m | 933.06m | 82.00 | -- | 6.88 | -- | 381.31 | -23.64 | -23.64 | 0.3719 | 7.92 | 0.0241 | -- | -- | 29,841.46 | -121.41 | -74.04 | -161.17 | -85.12 | -- | -- | -5,037.88 | -24,589.25 | -- | -- | 0.00 | -- | -- | -- | 42.40 | -- | -4.52 | -- |
Bicycle Therapeutics PLC (ADR) | 41.61m | -168.16m | 933.24m | 284.00 | -- | -- | -- | 22.43 | -4.45 | -4.45 | 1.08 | -- | -- | -- | -- | 146,514.10 | -- | -29.45 | -- | -32.98 | -- | -- | -404.14 | -571.36 | -- | -- | -- | -- | 86.52 | 30.47 | -60.28 | -- | 19.82 | -- |
Tyra Biosciences Inc | 0.00 | -69.13m | 937.55m | 49.00 | -- | 3.76 | -- | -- | -1.62 | -1.62 | 0.00 | 4.75 | 0.00 | -- | -- | 0.00 | -28.10 | -- | -29.36 | -- | -- | -- | -- | -- | -- | -- | 0.00 | -- | -- | -- | -24.96 | -- | -- | -- |
Immunome Inc | 14.02m | -106.81m | 944.11m | 55.00 | -- | 5.68 | -- | 67.35 | -3.33 | -3.33 | 0.7064 | 2.77 | 0.1625 | -- | -- | 254,872.70 | -123.77 | -94.54 | -148.94 | -112.66 | -- | -- | -761.92 | -1,403.15 | -- | -- | 0.00 | -- | -- | -- | -184.68 | -- | 29.52 | -- |
ARS Pharmaceuticals Inc | 30.00k | -54.37m | 944.72m | 24.00 | -- | 4.07 | -- | 31,490.68 | -0.5719 | -0.5719 | 0.0003 | 2.39 | 0.0001 | -- | -- | 1,250.00 | -21.13 | -20.37 | -21.45 | -21.32 | -- | -- | -181,216.70 | -17,491.75 | -- | -- | 0.00 | -- | -97.72 | -- | -56.75 | -- | -17.18 | -- |
Centessa Pharmaceuticals PLC - ADR | 6.85m | -151.09m | 949.90m | 76.00 | -- | 3.96 | -- | 138.61 | -1.57 | -1.57 | 0.0713 | 2.39 | 0.017 | -- | 0.2081 | 90,171.05 | -37.56 | -- | -41.57 | -- | -- | -- | -2,204.66 | -- | -- | -- | 0.2427 | -- | -- | -- | 30.12 | -- | -- | -- |
Cassava Sciences Inc | 0.00 | -97.22m | 953.57m | 29.00 | -- | 6.77 | -- | -- | -2.32 | -2.32 | 0.00 | 3.25 | 0.00 | -- | -- | 0.00 | -50.31 | -30.74 | -53.23 | -32.12 | -- | -- | -- | -- | -- | -- | 0.00 | -- | -- | -- | -27.50 | -- | -- | -- |
Ocular Therapeutix Inc | 58.44m | -80.74m | 954.66m | 267.00 | -- | 7.78 | -- | 16.34 | -0.9939 | -0.9939 | 0.7233 | 0.7927 | 0.2912 | 2.47 | 2.46 | 218,883.90 | -40.23 | -46.70 | -48.19 | -54.18 | 90.96 | 89.36 | -138.15 | -228.65 | 6.59 | -6.57 | 0.4512 | -- | 13.49 | 96.60 | -13.65 | -- | 26.37 | -- |
Innoviva Inc | 310.46m | 179.72m | 961.06m | 112.00 | 6.78 | 1.43 | 4.46 | 3.10 | 2.24 | 2.24 | 3.96 | 10.66 | 0.2509 | 0.8825 | 4.19 | 2,771,991.00 | 14.52 | 26.24 | 15.62 | 28.53 | 86.27 | -- | 57.89 | 76.84 | 7.96 | -- | 0.398 | -- | -6.30 | 3.53 | -15.99 | -14.57 | -- | -- |
Liquidia Corp | 17.49m | -78.50m | 972.40m | 136.00 | -- | 18.56 | -- | 55.60 | -1.21 | -1.21 | 0.2691 | 0.6891 | 0.1413 | -- | 3.85 | 128,588.20 | -63.43 | -55.02 | -71.31 | -62.69 | 83.49 | 82.18 | -448.89 | -474.59 | -- | -26.14 | 0.4942 | -- | 9.75 | 45.23 | -91.40 | -- | 66.93 | -- |
MacroGenics Inc | 58.75m | -9.06m | 980.32m | 339.00 | -- | 6.37 | 1,672.91 | 16.69 | -0.1525 | -0.1525 | 0.9462 | 2.46 | 0.203 | 6.15 | 1.76 | 173,300.90 | -3.13 | -37.76 | -3.82 | -45.53 | 86.00 | -- | -15.42 | -133.96 | 4.46 | -117.57 | 0.00 | -- | -61.33 | -0.4606 | 92.44 | -- | -41.13 | -- |
Viridian Therapeutics Inc | 314.00k | -237.73m | 982.87m | 96.00 | -- | 3.53 | -- | 3,130.15 | -5.32 | -5.32 | 0.007 | 8.19 | 0.0007 | -- | 3.08 | 3,340.43 | -51.37 | -55.59 | -54.93 | -60.32 | -- | -- | -75,711.47 | -5,678.12 | -- | -- | 0.0437 | -- | -82.28 | -48.16 | -83.05 | -- | 15.08 | -- |
Holder | Shares | % Held |
---|---|---|
BVF Partners LPas of 31 Dec 2023 | 8.77m | 8.99% |
EcoR1 Capital, LLCas of 31 Dec 2023 | 5.62m | 5.76% |
Adage Capital Management LPas of 31 Dec 2023 | 2.90m | 2.97% |
Fidelity Management & Research Co. LLCas of 31 Dec 2023 | 2.79m | 2.86% |
T. Rowe Price Associates, Inc. (Investment Management)as of 31 Dec 2023 | 2.54m | 2.60% |
Octagon Capital Advisors LPas of 31 Dec 2023 | 2.06m | 2.11% |
Point72 Asset Management LPas of 31 Dec 2023 | 1.84m | 1.89% |
Morgan Stanley & Co. LLCas of 31 Dec 2023 | 1.21m | 1.24% |
Franklin Advisers, Inc.as of 31 Dec 2023 | 1.12m | 1.14% |
Invus Public Equities Advisors LLCas of 31 Dec 2023 | 1.01m | 1.04% |