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About the company
2seventy bio, Inc. is a cell and gene therapy company focused on the research, development, and commercialization of transformative treatments for cancer. The Company is focused on the commercialization and development of Abecma (idecabtagene vicleucel). Abecma is its B cell maturation antigen (BCMA)-targeted CAR T cell therapy for multiple myeloma, in collaboration with their partner Bristol Myers Squibb (BMS). ABECMA is a BCMA-directed genetically modified autologous T cell immunotherapy indicated for the treatment of adult patients with relapsed or refractory multiple myeloma after four or more prior lines of therapy, including an immunomodulatory agent, a proteasome inhibitor, and an anti-CD38 monoclonal antibody. Abecma uses a lentiviral vector (LVV), to deliver a chimeric antigen receptor (CAR), with the potential to program a patient’s own T cells to recognize the plasma cell specific BCMA, protein on the cell surface.
- Revenue in USD (TTM)45.62m
- Net income in USD-94.55m
- Incorporated2021
- Employees274.00
- Location2Seventy Bio Inc60 Binney StreetCAMBRIDGE 02210United StatesUSA
- Phone+1 (339) 499-9300
- Fax+1 (302) 636-5454
- Websitehttps://www.2seventybio.com/
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Peer analysis
Key Information
- Key Information
- Stock Performance
- Per Share Data
- Efficiency
- Management Effectiveness
- Profitability
- Financial Strength
- Growth Rates
| Company | Revenue (TTM) | Net income (TTM) | Market cap | Employees | Price/earnings (TTM) | Price/book value (MRQ) | Price/cash flow (TTM) | Price/sales (TTM) | EPS (excl. extraordinary items, TTM) | EPS (incl. extraordinary items, TTM) | Revenue per share (TTM) | Book value per share (MRQ) | Asset turnover (TTM) | Inventory turnover (TTM) | Receivables turnover (TTM) | Revenues per employee (TTM) | Return on avg assets (TTM) | Return on avg assets (5 yr avg) | Return on investment (TTM) | Return on investment (5 yr avg) | Gross margin (TTM) | Gross margin (5 yr avg) | Net profit margin (TTM) | Net Profit margin (5 yr avg) | Quick ratio (MRQ) | Interest coverage (TTM) | Total debt to capital (MRQ) | Payout ratio (5 yr avg) | Revenue (YOY change %) | Revenue (5 yr growth rate) | Net income (YOY change %) | Net income (5 yr growth rate) | Capital expenditure (5 yr growth rate) | Dividend (5 yr growth rate) |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Sagimet Biosciences Inc | 0.00 | -37.52m | 145.52m | 10.00 | -- | 0.8526 | -- | -- | -1.29 | -1.29 | 0.00 | 5.30 | 0.00 | -- | -- | 0.00 | -27.02 | -- | -27.94 | -- | -- | -- | -- | -- | -- | -- | 0.00 | -- | -- | -- | 8.60 | -- | -- | -- |
| Achieve Life Sciences Inc | 0.00 | -32.94m | 147.84m | 22.00 | -- | 4.72 | -- | -- | -1.13 | -1.13 | 0.00 | 0.9124 | 0.00 | -- | -- | 0.00 | -91.19 | -86.31 | -107.21 | -119.59 | -- | -- | -- | -- | -- | -22.54 | 0.2384 | -- | -- | -- | 29.60 | -- | -14.51 | -- |
| Atossa Therapeutics Inc | 0.00 | -26.91m | 150.91m | 10.00 | -- | 2.05 | -- | -- | -0.2144 | -0.2144 | 0.00 | 0.5857 | 0.00 | -- | -- | 0.00 | -29.71 | -29.97 | -31.30 | -32.55 | -- | -- | -- | -- | -- | -- | 0.00 | -- | -- | -- | -11.62 | -- | -33.90 | -- |
| Instil Bio Inc | 0.00 | -75.17m | 151.93m | 49.00 | -- | 0.8645 | -- | -- | -11.56 | -11.56 | 0.00 | 27.02 | 0.00 | -- | -- | 0.00 | -24.53 | -- | -25.52 | -- | -- | -- | -- | -- | -- | -492.20 | 0.3179 | -- | -- | -- | 30.06 | -- | -- | -- |
| Gossamer Bio Inc | 105.32m | -71.65m | 157.83m | 135.00 | -- | 2.92 | -- | 1.50 | -0.3283 | -0.3283 | 0.4595 | 0.2389 | 0.3014 | -- | -- | 780,162.90 | -20.51 | -57.43 | -23.67 | -64.38 | -- | -- | -68.03 | -- | -- | -6.84 | 0.7847 | -- | -- | -- | 21.61 | -- | -- | -- |
| 2Seventy Bio Inc | 45.62m | -94.55m | 160.16m | 274.00 | -- | 0.7023 | -- | 3.51 | -1.85 | -1.85 | 0.8659 | 4.43 | 0.0797 | -- | 2.18 | 166,496.30 | -16.52 | -- | -18.31 | -- | 65.72 | 91.76 | -207.25 | -223.57 | -- | -- | 0.00 | -- | 9.72 | 12.96 | 14.39 | -- | -22.88 | -- |
| Checkpoint Therapeutics Inc | 47.00k | -46.47m | 165.05m | 23.00 | -- | -- | -- | 3,511.78 | -1.44 | -1.44 | 0.0013 | -0.2749 | 0.0127 | -- | -- | 2,043.48 | -1,256.40 | -142.43 | -- | -342.79 | -- | -- | -98,868.09 | -6,554.97 | -- | -- | -- | -- | -46.35 | -50.61 | 17.21 | -- | -- | -- |
| Actuate Therapeutics Inc | -100.00bn | -100.00bn | 167.58m | 11.00 | -- | 31.27 | -- | -- | -- | -- | -- | 0.2744 | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | 0.0703 | -- | -- | -- | -22.74 | -- | -- | -- |
| Verastem Inc | 10.00m | -93.45m | 168.68m | 73.00 | -- | 13.80 | -- | 16.87 | -3.18 | -3.18 | 0.3311 | 0.8002 | 0.0661 | -- | 100.00 | 136,986.30 | -61.78 | -62.70 | -77.44 | -75.18 | -- | -- | -934.54 | -406.17 | -- | -- | 0.5579 | -- | -100.00 | -- | -18.36 | -- | -- | -- |
| Greenwich Lifesciences Inc | 0.00 | -10.50m | 168.91m | 3.00 | -- | 33.90 | -- | -- | -0.8111 | -0.8111 | 0.00 | 0.3791 | 0.00 | -- | -- | 0.00 | -140.17 | -36.43 | -151.72 | -38.31 | -- | -- | -- | -- | -- | -- | 0.00 | -- | -- | -- | -13.63 | -- | -- | -- |
| Heron Therapeutics Inc | 137.74m | -27.97m | 169.87m | 126.00 | -- | -- | -- | 1.23 | -0.1841 | -0.1841 | 0.9067 | -0.2637 | 0.6122 | 0.871 | 2.11 | 1,093,151.00 | -12.43 | -53.55 | -19.65 | -71.24 | 72.19 | 52.52 | -20.30 | -170.12 | 1.74 | -- | 1.36 | -- | 17.99 | 10.40 | 39.26 | -- | -29.97 | -- |
| Adaptimmune Therapeutics PLC - ADR | 175.04m | -44.52m | 169.99m | 449.00 | -- | 2.12 | -- | 0.9712 | -0.2126 | -0.2126 | 0.7109 | 0.3128 | 0.5701 | -- | 26.34 | 389,846.30 | -14.50 | -41.19 | -18.73 | -48.21 | -- | -- | -25.43 | -714.26 | 3.82 | -- | 0.384 | -- | 122.05 | 0.2595 | 31.18 | -- | 0.7202 | -- |
| DiaMedica Therapeutics Inc | 0.00 | -21.71m | 171.85m | 18.00 | -- | 3.58 | -- | -- | -0.5527 | -0.5527 | 0.00 | 1.12 | 0.00 | -- | -- | 0.00 | -39.23 | -45.38 | -41.66 | -48.24 | -- | -- | -- | -- | -- | -- | 0.0055 | -- | -- | -- | -41.72 | -- | -13.65 | -- |
| Galectin Therapeutics Inc | 0.00 | -45.23m | 175.31m | 14.00 | -- | -- | -- | -- | -0.7284 | -0.7284 | 0.00 | -1.48 | 0.00 | -- | -- | 0.00 | -176.31 | -92.08 | -587.13 | -121.97 | -- | -- | -- | -- | -- | -7.18 | 8.66 | -- | -- | -- | -15.26 | -- | -- | -- |
| Tenaya Therapeutics Inc | 0.00 | -117.23m | 175.87m | 140.00 | -- | 1.56 | -- | -- | -1.44 | -1.44 | 0.00 | 1.42 | 0.00 | -- | -- | 0.00 | -70.20 | -- | -78.56 | -- | -- | -- | -- | -- | -- | -- | 0.00 | -- | -- | -- | -0.3388 | -- | -- | -- |
| Nkarta Inc | 0.00 | -110.61m | 176.42m | 159.00 | -- | 0.4095 | -- | -- | -1.87 | -1.87 | 0.00 | 6.11 | 0.00 | -- | -- | 0.00 | -23.59 | -32.39 | -24.86 | -34.05 | -- | -- | -- | -372,519.20 | -- | -- | 0.00 | -- | -- | -- | -3.22 | -- | 106.05 | -- |
Data as of Nov 21 2024. Currency figures normalised to 2Seventy Bio Inc's reporting currency: US Dollar USD
60.13%Per cent of shares held by top holders
| Holder | Shares | % Held |
|---|---|---|
| Kynam Capital Management LPas of 30 Sep 2024 | 5.95m | 11.56% |
| Goldman Sachs & Co. LLC (Private Banking)as of 30 Sep 2024 | 4.17m | 8.11% |
| The Vanguard Group, Inc.as of 30 Sep 2024 | 3.73m | 7.24% |
| BlackRock Fund Advisorsas of 30 Sep 2024 | 3.46m | 6.72% |
| Morgan Stanley & Co. LLCas of 30 Sep 2024 | 2.71m | 5.27% |
| Madison Avenue Partners LPas of 30 Sep 2024 | 2.56m | 4.98% |
| Newtyn Management LLCas of 30 Sep 2024 | 2.54m | 4.93% |
| Baker Bros. Advisors LPas of 30 Sep 2024 | 2.50m | 4.85% |
| Casdin Capital LLCas of 30 Sep 2024 | 2.00m | 3.88% |
| DWS Investments (UK) Ltd.as of 30 Sep 2024 | 1.33m | 2.58% |
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Data from 30 Sep 2024 - 30 Sep 2024Source: FactSet Research Systems Inc.
