Form 8.3 - Amgen Inc- Replacement – Company Announcement

Wells Fargo & Co, Amgen Inc

Form 8.3 - Amgen Inc- Replacement

Dec 02 2022 07:00 GMTSource: RNS

RNS Number : 3590I

Wells Fargo & Company

02 December 2022

Ap27

Amendment - This form replaces RNS number 3321I.

Changes were made to section 2 and 3(a) of the form

FORM 8.3

IRISH TAKEOVER PANEL

OPENING POSITION DISCLOSURE/DEALING DISCLOSURE UNDER RULE 8.3 OF THE IRISH TAKEOVER PANEL ACT, 1997, TAKEOVER

RULES, 2022 BY PERSONS WITH INTERESTS IN RELEVANT SECURITIES REPRESENTING 1% OR MORE

1. KEY INFORMATION

(a) Full name of discloser	Wells Fargo & Co.
(b) Owner or controller of interests and short positions disclosed, if different from 1(a) The naming of nominee or vehicle companies is insufficient. For a trust, the trustee(s), settlor and beneficiaries must be named.
(c) Name of offeror/offeree in relation to whose relevant securities this form relates Use a separate form for each offeror/offeree	Amgen Inc
(d) If an exempt fund manager connected with an offeror/offeree, state this and specify identity of offeror/offeree (Note 1)
(e) Date position held/dealing undertaken For an opening position disclosure, state the latest practicable date prior to the disclosure	30/11/2022
(f) In addition to the company in 1(c) above, is the discloser also making disclosures in respect of any other party to the offer? If it is a cash offer or possible cash offer, state "N/A"	YES / NO / N/A If YES, specify which: NO

2. INTERESTS AND SHORT POSITIONS

If there are interests and short positions to disclose in more than one class of relevant securities of the offeror or offeree named in 1(c), copy table 2 for each additional class of relevant security.

Ap28

Interests and short positions in the relevant securities of the offeror or offeree to which the disclosure relates following the dealing (if any)

(Note 2)

Class of relevant security (Note 3)	Common Stock (US0311621009)
	Interests		Short positions
	Number	%	Number	%
(1) Relevant securities owned and/or controlled	7,398,044	1.386	0	0
(2) Cash-settled derivatives	0	0	0	0
(3) Stock-settled derivatives (including options) and agreements to purchase/ sell	7,700	0.001	82,000	0.015
Total	7,405,744	1.388	82,000	0.015

All interests and all short positions should be disclosed.

Details of options including rights to subscribe for new securities and any open stock-settled derivative positions (including traded options), or agreements to purchase or sell relevant securities, should be given on a Supplemental Form 8.

3. DEALINGS (IF ANY) BY THE PERSON MAKING THE DISCLOSURE (Note 4)

Where there have been dealings in more than one class of relevant securities of the offeror or offeree named in 1(c), copy table 3(a), (b), (c) or (d) (as appropriate) for each additional class of relevant security dealt in.

The currency of all prices and other monetary amounts should be stated.

(a) Purchases and sales

Class of relevant security	Purchase/sale	Number of securities	Price per unit (Note 5) USD
Common Shares	Sale	200	282.51
Common Shares	Sale	74	285.64
Common Shares	Sale	50	279.68
Common Shares	Sale	47	280.37
Common Shares	Sale	47	283.65
Common Shares	Sale	35	280.52
Common Shares	Sale	32	283.43
Common Shares	Sale	30	283.59
Common Shares	Sale	29	282.58
Common Shares	Sale	27	281.13
Common Shares	Sale	27	280.48
Common Shares	Sale	24	281.07
Common Shares	Sale	24	280.44
Common Shares	Sale	23	279.7
Common Shares	Sale	20	279.06
Common Shares	Sale	19	285.95
Common Shares	Sale	18	284.58
Common Shares	Sale	18	279.04
Common Shares	Sale	18	279.93
Common Shares	Sale	16	279.75
Common Shares	Sale	16	280.57
Common Shares	Sale	12	280.89
Common Shares	Sale	12	280.32
Common Shares	Sale	11	279.28
Common Shares	Sale	10	280.68
Common Shares	Sale	10	279.99
Common Shares	Sale	10	280.72
Common Shares	Sale	9	279.21
Common Shares	Sale	9	281.9
Common Shares	Sale	9	285.96
Common Shares	Sale	9	285.96
Common Shares	Sale	9	280.47
Common Shares	Sale	9	279.88
Common Shares	Sale	9	280.03
Common Shares	Sale	8	279.29
Common Shares	Sale	8	280.28
Common Shares	Sale	7	280.62
Common Shares	Sale	7	282.01
Common Shares	Sale	7	285.15
Common Shares	Sale	7	280.02
Common Shares	Sale	7	280.13
Common Shares	Sale	7	279.89
Common Shares	Sale	6	285.96
Common Shares	Sale	6	279.3
Common Shares	Sale	6	282.62
Common Shares	Sale	6	284.13
Common Shares	Sale	6	279.7
Common Shares	Sale	6	282.74
Common Shares	Sale	6	279.58
Common Shares	Sale	6	280.5
Common Shares	Sale	5	279.99
Common Shares	Sale	5	279.39
Common Shares	Sale	5	285.96
Common Shares	Sale	5	281.17
Common Shares	Sale	5	282.26
Common Shares	Sale	5	280.77
Common Shares	Sale	5	283.54
Common Shares	Sale	5	280.77
Common Shares	Sale	4	279.58
Common Shares	Sale	4	279.06
Common Shares	Sale	4	281.91
Common Shares	Sale	4	282.53
Common Shares	Sale	4	281.91
Common Shares	Sale	4	280.02
Common Shares	Sale	4	279.89
Common Shares	Sale	4	284
Common Shares	Sale	4	285.99
Common Shares	Sale	4	286.16
Common Shares	Sale	4	280.5
Common Shares	Sale	4	279.58
Common Shares	Sale	4	282.56
Common Shares	Sale	4	280.08
Common Shares	Sale	4	280.15
Common Shares	Sale	4	279.58
Common Shares	Sale	4	283.61
Common Shares	Sale	4	279.6
Common Shares	Sale	4	280.02
Common Shares	Sale	3	279.91
Common Shares	Sale	3	279.49
Common Shares	Sale	3	286.06
Common Shares	Sale	3	279.06
Common Shares	Sale	3	280.44
Common Shares	Sale	3	286.12
Common Shares	Sale	3	280.44
Common Shares	Sale	3	279.99
Common Shares	Sale	3	279.99
Common Shares	Sale	3	279.67
Common Shares	Sale	3	282.56
Common Shares	Sale	3	284.87
Common Shares	Sale	3	279.46
Common Shares	Sale	3	280.44
Common Shares	Sale	3	279.99
Common Shares	Sale	3	279.58
Common Shares	Sale	3	279.58
Common Shares	Sale	3	281.11
Common Shares	Sale	3	279.88
Common Shares	Sale	3	286.04
Common Shares	Sale	3	280.15
Common Shares	Sale	3	279.99
Common Shares	Sale	3	281.05
Common Shares	Sale	3	280.04
Common Shares	Sale	3	280.13
Common Shares	Sale	3	280.06
Common Shares	Sale	3	284.75
Common Shares	Sale	3	286.12
Common Shares	Sale	3	279.39
Common Shares	Sale	3	283.66
Common Shares	Sale	3	279.46
Common Shares	Sale	3	286.12
Common Shares	Sale	3	279.99
Common Shares	Sale	3	283.49
Common Shares	Sale	2	279.88
Common Shares	Sale	2	279.39
Common Shares	Sale	2	283.43
Common Shares	Sale	2	279.99
Common Shares	Sale	2	280.06
Common Shares	Sale	2	286.12
Common Shares	Sale	2	280.06
Common Shares	Sale	2	279.49
Common Shares	Sale	2	280.09
Common Shares	Sale	2	279.49
Common Shares	Sale	2	285.03
Common Shares	Sale	2	280.11
Common Shares	Sale	2	282.56
Common Shares	Sale	2	279.99
Common Shares	Sale	2	285.72
Common Shares	Sale	2	280.79
Common Shares	Sale	2	279.49
Common Shares	Sale	2	280.44
Common Shares	Sale	2	285.75
Common Shares	Sale	2	285.62
Common Shares	Sale	2	284.87
Common Shares	Sale	2	283.43
Common Shares	Sale	2	286.12
Common Shares	Sale	2	279.88
Common Shares	Sale	2	279.88
Common Shares	Sale	2	280.44
Common Shares	Sale	2	279.49
Common Shares	Sale	2	283.61
Common Shares	Sale	2	279.58
Common Shares	Sale	2	284.79
Common Shares	Sale	2	279.88
Common Shares	Sale	2	279.6
Common Shares	Sale	2	280.43
Common Shares	Sale	2	282.71
Common Shares	Sale	2	279.99
Common Shares	Sale	2	286.12
Common Shares	Sale	2	280.44
Common Shares	Sale	2	280.09
Common Shares	Sale	2	280.06
Common Shares	Sale	2	279.21
Common Shares	Sale	2	282.56
Common Shares	Sale	2	279.88
Common Shares	Sale	2	279.88
Common Shares	Sale	2	279.24
Common Shares	Sale	2	280.32
Common Shares	Sale	2	283.43
Common Shares	Sale	2	280.43
Common Shares	Sale	2	279.39
Common Shares	Sale	2	286.12
Common Shares	Sale	2	279.88
Common Shares	Sale	2	279.69
Common Shares	Sale	2	282.62
Common Shares	Sale	2	279.49
Common Shares	Sale	2	279.99
Common Shares	Sale	2	279.21
Common Shares	Sale	2	280.41
Common Shares	Sale	2	279.36
Common Shares	Sale	2	279.06
Common Shares	Sale	2	279.55
Common Shares	Sale	2	283.54
Common Shares	Sale	2	279.52
Common Shares	Sale	2	286.12
Common Shares	Sale	2	284.85
Common Shares	Sale	2	280.38
Common Shares	Sale	2	279.5
Common Shares	Sale	2	279.99
Common Shares	Sale	2	283.43
Common Shares	Sale	2	279.88
Common Shares	Sale	2	279.99
Common Shares	Sale	2	280.37
Common Shares	Sale	2	283.54
Common Shares	Sale	2	279.27
Common Shares	Sale	1	279.58
Common Shares	Sale	1	279.3
Common Shares	Sale	1	280.03
Common Shares	Sale	1	284.87
Common Shares	Sale	1	279.99
Common Shares	Sale	1	279.99
Common Shares	Sale	1	279.9
Common Shares	Sale	1	279.99
Common Shares	Sale	1	281.07
Common Shares	Sale	1	279.74
Common Shares	Sale	1	286.15
Common Shares	Sale	1	279.99
Common Shares	Sale	1	279.58
Common Shares	Sale	1	283.43
Common Shares	Sale	1	279.58
Common Shares	Sale	1	279.99
Common Shares	Sale	1	283.54
Common Shares	Sale	1	283.43
Common Shares	Sale	1	280.44
Common Shares	Sale	1	279.54
Common Shares	Sale	1	279.58
Common Shares	Sale	1	279.99
Common Shares	Sale	1	279.99
Common Shares	Sale	1	280.83
Common Shares	Sale	1	279.49
Common Shares	Sale	1	279.62
Common Shares	Sale	1	279.49
Common Shares	Sale	1	285.51
Common Shares	Sale	1	279.58
Common Shares	Sale	1	279.95
Common Shares	Sale	1	279.58
Common Shares	Sale	1	279.21
Common Shares	Sale	1	279.94
Common Shares	Sale	1	279.49
Common Shares	Sale	1	279.3
Common Shares	Sale	1	285.93
Common Shares	Sale	1	279.21
Common Shares	Sale	1	280.2
Common Shares	Sale	1	283.43
Common Shares	Sale	1	280.27
Common Shares	Sale	1	279.99
Common Shares	Sale	1	280.44
Common Shares	Sale	1	279.99
Common Shares	Sale	1	279.68
Common Shares	Sale	1	279.62
Common Shares	Sale	1	282.56
Common Shares	Sale	1	286
Common Shares	Sale	1	279.58
Common Shares	Sale	1	280.44
Common Shares	Sale	1	279.73
Common Shares	Sale	1	280.03
Common Shares	Sale	1	283.43
Common Shares	Sale	1	279.62
Common Shares	Sale	1	279.39
Common Shares	Sale	1	279.99
Common Shares	Sale	1	279.99
Common Shares	Sale	1	286.12
Common Shares	Sale	1	280.44
Common Shares	Sale	1	279.99
Common Shares	Sale	1	280.19
Common Shares	Sale	1	280.44
Common Shares	Sale	1	280.21
Common Shares	Sale	1	279.99
Common Shares	Sale	1	286.7
Common Shares	Sale	1	283.43
Common Shares	Sale	1	279.46
Common Shares	Sale	1	279.49
Common Shares	Sale	1	279.58
Common Shares	Sale	1	279.99
Common Shares	Sale	1	280.47
Common Shares	Sale	1	280.12
Common Shares	Sale	1	279.88
Common Shares	Sale	1	282.37
Common Shares	Sale	1	282.71
Common Shares	Sale	1	286
Common Shares	Sale	1	279.58
Common Shares	Sale	1	280.06
Common Shares	Sale	1	283.43
Common Shares	Sale	1	279.69
Common Shares	Sale	1	279.58
Common Shares	Sale	1	283.43
Common Shares	Sale	1	279.58
Common Shares	Sale	1	283.86
Common Shares	Sale	1	279.49
Common Shares	Sale	1	279.46
Common Shares	Sale	1	280.77
Common Shares	Sale	1	282.07
Common Shares	Sale	1	279.88
Common Shares	Sale	1	279.99
Common Shares	Sale	1	280.44
Common Shares	Sale	1	279.58
Common Shares	Sale	1	279.99
Common Shares	Sale	1	279.64
Common Shares	Sale	1	283.54
Common Shares	Sale	1	280.47
Common Shares	Sale	1	280.26
Common Shares	Sale	1	284.85
Common Shares	Sale	1	279.58
Common Shares	Sale	1	279.69
Common Shares	Sale	1	286.12
Common Shares	Sale	1	279.99
Common Shares	Sale	1	279.99
Common Shares	Sale	1	279.68
Common Shares	Sale	1	279.88
Common Shares	Sale	1	279.9
Common Shares	Sale	1	280.47
Common Shares	Sale	1	280.44
Common Shares	Sale	1	280.47
Common Shares	Sale	1	280.06
Common Shares	Sale	1	279.97
Common Shares	Sale	1	279.49
Common Shares	Sale	1	280.83
Common Shares	Sale	1	285.65
Common Shares	Sale	1	283.43
Common Shares	Sale	1	279.99
Common Shares	Sale	1	284.57
Common Shares	Sale	1	279.51
Common Shares	Sale	1	280.49
Common Shares	Sale	1	284.87
Common Shares	Sale	1	279.99
Common Shares	Sale	1	279.49
Common Shares	Sale	1	279.99
Common Shares	Sale	1	279.99
Common Shares	Sale	1	279.62
Common Shares	Sale	1	279.58
Common Shares	Sale	1	280.44
Common Shares	Sale	1	281.1
Common Shares	Sale	1	279.21
Common Shares	Sale	1	283.54
Common Shares	Sale	1	280.02
Common Shares	Sale	1	279.88
Common Shares	Sale	1	279.99
Common Shares	Sale	1	279.49
Common Shares	Sale	1	279.99
Common Shares	Sale	1	279.99
Common Shares	Sale	1	280.44
Common Shares	Sale	1	286.12
Common Shares	Sale	1	280.44
Common Shares	Sale	1	279.88
Common Shares	Sale	1	279.6
Common Shares	Sale	1	279.6
Common Shares	Sale	1	279.49
Common Shares	Sale	1	280.44
Common Shares	Sale	1	280.06
Common Shares	Sale	1	280.44
Common Shares	Sale	1	283.76
Common Shares	Sale	1	279.99
Common Shares	Sale	1	279.99
Common Shares	Sale	1	280.44
Common Shares	Sale	1	283.43
Common Shares	Sale	1	280.27
Common Shares	Sale	1	280.44
Common Shares	Sale	1	279.99
Common Shares	Sale	1	280.64
Common Shares	Sale	1	279.58
Common Shares	Sale	1	279.58
Common Shares	Sale	1	279.25
Common Shares	Sale	1	279.99
Common Shares	Sale	1	279.99
Common Shares	Sale	1	280.44
Common Shares	Sale	1	279.99
Common Shares	Sale	1	280.44
Common Shares	Sale	1	282.6
Common Shares	Sale	1	280.13
Common Shares	Sale	1	279.62
Common Shares	Sale	1	280.44
Common Shares	Sale	1	279.21
Common Shares	Sale	1	279.99
Common Shares	Sale	1	279.27
Common Shares	Sale	1	279.99
Common Shares	Sale	1	279.99
Common Shares	Sale	1	286.11
Common Shares	Sale	1	279.99
Common Shares	Sale	1	279.88
Common Shares	Sale	1	280.15
Common Shares	Sale	1	280.06
Common Shares	Sale	1	279.99
Common Shares	Sale	1	280.44
Common Shares	Sale	1	281.24
Common Shares	Sale	1	279.88
Common Shares	Sale	1	279.99
Common Shares	Sale	1	280.44
Common Shares	Sale	1	279.46
Common Shares	Sale	1	282.45
Common Shares	Sale	1	279.49
Common Shares	Sale	1	279.58
Common Shares	Sale	1	279.62
Common Shares	Sale	1	279.6
Common Shares	Sale	1	279.58
Common Shares	Sale	1	280.44
Common Shares	Sale	1	279.46
Common Shares	Sale	1	284.92
Common Shares	Sale	1	279.88
Common Shares	Sale	1	282.14
Common Shares	Sale	1	286.12
Common Shares	Sale	1	279.88
Common Shares	Sale	1	279.99
Common Shares	Sale	1	280.44
Common Shares	Sale	1	280.03
Common Shares	Sale	1	280.21
Common Shares	Sale	1	286.12
Common Shares	Sale	1	279.97
Common Shares	Sale	1	279.99
Common Shares	Sale	1	279.58
Common Shares	Sale	1	280.44
Common Shares	Sale	1	280.06
Common Shares	Sale	1	280.06
Common Shares	Sale	1	279.25
Common Shares	Sale	1	279.58
Common Shares	Sale	1	280.44
Common Shares	Sale	1	281.84
Common Shares	Sale	1	279.58
Common Shares	Sale	1	280.47
Common Shares	Sale	1	280.47
Common Shares	Sale	1	279.88
Common Shares	Sale	1	286.12
Common Shares	Sale	1	280.02
Common Shares	Sale	1	279.3
Common Shares	Sale	1	279.99
Common Shares	Sale	1	279.99
Common Shares	Sale	1	280.43
Common Shares	Sale	1	280.03
Common Shares	Sale	1	280.15
Common Shares	Sale	1	279.62
Common Shares	Sale	1	280.06
Common Shares	Sale	1	279.49
Common Shares	Sale	1	279.99
Common Shares	Sale	1	284.8
Common Shares	Sale	1	279.99
Common Shares	Sale	10	280.34
Common Shares	Sale	2	279.95
Common Shares	Sale	100	286.62
Common Shares	Sale	100	286.56
Common Shares	Sale	25	286.63
Common Shares	Purchase	1	279.99
Common Shares	Purchase	1	285.79
Common Shares	Purchase	1	280.43
Common Shares	Purchase	1	281.36
Common Shares	Purchase	1	280.37
Common Shares	Purchase	1	279.91
Common Shares	Purchase	1	280.1
Common Shares	Purchase	1	283.7
Common Shares	Purchase	1	285.79
Common Shares	Purchase	1	279.92
Common Shares	Purchase	1	285.79
Common Shares	Purchase	1	279.92
Common Shares	Purchase	1	280.1
Common Shares	Purchase	1	279.18
Common Shares	Purchase	1	280.46
Common Shares	Purchase	1	285.33
Common Shares	Purchase	1	280.46
Common Shares	Purchase	1	279.09
Common Shares	Purchase	1	280.1
Common Shares	Purchase	1	281.36
Common Shares	Purchase	1	279.65
Common Shares	Purchase	1	281.36
Common Shares	Purchase	1	286.24
Common Shares	Purchase	1	285.79
Common Shares	Purchase	1	280.1
Common Shares	Purchase	1	279.8
Common Shares	Purchase	1	281.83
Common Shares	Purchase	1	281.1
Common Shares	Purchase	1	280.44
Common Shares	Purchase	1	280
Common Shares	Purchase	1	285.79
Common Shares	Purchase	1	280.1
Common Shares	Purchase	1	280.1
Common Shares	Purchase	1	280
Common Shares	Purchase	1	281.37
Common Shares	Purchase	1	280.48
Common Shares	Purchase	1	279.12
Common Shares	Purchase	1	280
Common Shares	Purchase	1	283.66
Common Shares	Purchase	1	285.79
Common Shares	Purchase	1	280.1
Common Shares	Purchase	1	281.83
Common Shares	Purchase	1	279.78
Common Shares	Purchase	1	285.79
Common Shares	Purchase	1	281.83
Common Shares	Purchase	1	280.7
Common Shares	Purchase	1	280.38
Common Shares	Purchase	1	279.67
Common Shares	Purchase	1	280.1
Common Shares	Purchase	1	283.7
Common Shares	Purchase	1	280.1
Common Shares	Purchase	1	281.36
Common Shares	Purchase	1	285.79
Common Shares	Purchase	1	280.33
Common Shares	Purchase	1	280.1
Common Shares	Purchase	1	280.19
Common Shares	Purchase	1	285.79
Common Shares	Purchase	1	280.1
Common Shares	Purchase	1	282.56
Common Shares	Purchase	1	283.66
Common Shares	Purchase	1	280.1
Common Shares	Purchase	1	279.78
Common Shares	Purchase	1	280.24
Common Shares	Purchase	1	279.99
Common Shares	Purchase	1	279.99
Common Shares	Purchase	1	280.19
Common Shares	Purchase	1	281.36
Common Shares	Purchase	1	280.1
Common Shares	Purchase	1	279.24
Common Shares	Purchase	1	279.8
Common Shares	Purchase	1	281.36
Common Shares	Purchase	1	279.23
Common Shares	Purchase	1	283.7
Common Shares	Purchase	1	280.1
Common Shares	Purchase	1	280
Common Shares	Purchase	1	283.7
Common Shares	Purchase	1	283.81
Common Shares	Purchase	1	279.9
Common Shares	Purchase	1	285.79
Common Shares	Purchase	1	285.79
Common Shares	Purchase	1	280.1
Common Shares	Purchase	1	282.79
Common Shares	Purchase	1	279.24
Common Shares	Purchase	1	285.79
Common Shares	Purchase	1	282.79
Common Shares	Purchase	1	281.83
Common Shares	Purchase	1	279.99
Common Shares	Purchase	1	280.08
Common Shares	Purchase	1	285.79
Common Shares	Purchase	1	279.67
Common Shares	Purchase	1	279.8
Common Shares	Purchase	1	279.24
Common Shares	Purchase	1	279.67
Common Shares	Purchase	1	285.79
Common Shares	Purchase	1	279.99
Common Shares	Purchase	1	280.1
Common Shares	Purchase	1	280.1
Common Shares	Purchase	1	279.67
Common Shares	Purchase	1	285.83
Common Shares	Purchase	1	280.1
Common Shares	Purchase	1	282.06
Common Shares	Purchase	2	280.1
Common Shares	Purchase	2	280.58
Common Shares	Purchase	2	279.99
Common Shares	Purchase	2	279.09
Common Shares	Purchase	2	280.1
Common Shares	Purchase	2	281.36
Common Shares	Purchase	2	279.99
Common Shares	Purchase	2	285.76
Common Shares	Purchase	2	280.09
Common Shares	Purchase	2	280.1
Common Shares	Purchase	2	285.94
Common Shares	Purchase	2	280.1
Common Shares	Purchase	2	281.83
Common Shares	Purchase	2	280.1
Common Shares	Purchase	2	280.1
Common Shares	Purchase	2	280.53
Common Shares	Purchase	2	280.02
Common Shares	Purchase	2	279.99
Common Shares	Purchase	2	279.9
Common Shares	Purchase	2	279.99
Common Shares	Purchase	2	280.1
Common Shares	Purchase	2	281.36
Common Shares	Purchase	2	280.27
Common Shares	Purchase	2	280
Common Shares	Purchase	2	281.36
Common Shares	Purchase	2	279.6
Common Shares	Purchase	2	285.71
Common Shares	Purchase	2	279.67
Common Shares	Purchase	2	285.79
Common Shares	Purchase	2	279.95
Common Shares	Purchase	2	282.79
Common Shares	Purchase	2	283.66
Common Shares	Purchase	2	280.47
Common Shares	Purchase	2	279.68
Common Shares	Purchase	2	280.45
Common Shares	Purchase	2	281.36
Common Shares	Purchase	2	286.23
Common Shares	Purchase	2	281.36
Common Shares	Purchase	2	286.14
Common Shares	Purchase	2	280.03
Common Shares	Purchase	2	279.5
Common Shares	Purchase	2	280.75
Common Shares	Purchase	2	280
Common Shares	Purchase	2	279.24
Common Shares	Purchase	3	281.36
Common Shares	Purchase	3	279.09
Common Shares	Purchase	3	279.95
Common Shares	Purchase	3	279.99
Common Shares	Purchase	3	280.44
Common Shares	Purchase	3	280.44
Common Shares	Purchase	3	279.95
Common Shares	Purchase	3	280.58
Common Shares	Purchase	3	284.84
Common Shares	Purchase	3	279.72
Common Shares	Purchase	3	279.09
Common Shares	Purchase	3	285.58
Common Shares	Purchase	3	283.63
Common Shares	Purchase	3	280.44
Common Shares	Purchase	3	283.7
Common Shares	Purchase	3	281.83
Common Shares	Purchase	3	284.55
Common Shares	Purchase	3	283.73
Common Shares	Purchase	3	281.83
Common Shares	Purchase	3	280.38
Common Shares	Purchase	3	279.08
Common Shares	Purchase	3	280
Common Shares	Purchase	3	280.44
Common Shares	Purchase	3	280.02
Common Shares	Purchase	3	282.56
Common Shares	Purchase	3	280.1
Common Shares	Purchase	3	281.97
Common Shares	Purchase	3	281.36
Common Shares	Purchase	3	281.83
Common Shares	Purchase	3	279.09
Common Shares	Purchase	3	279.68
Common Shares	Purchase	3	279.09
Common Shares	Purchase	3	286.13
Common Shares	Purchase	3	279.95
Common Shares	Purchase	3	280.14
Common Shares	Purchase	4	279.99
Common Shares	Purchase	4	284.38
Common Shares	Purchase	4	281.03
Common Shares	Purchase	4	281.36
Common Shares	Purchase	4	279.09
Common Shares	Purchase	4	282.79
Common Shares	Purchase	4	280.91
Common Shares	Purchase	4	282
Common Shares	Purchase	4	279.67
Common Shares	Purchase	4	279.99
Common Shares	Purchase	4	280.5
Common Shares	Purchase	4	285.54
Common Shares	Purchase	4	280.75
Common Shares	Purchase	4	280.14
Common Shares	Purchase	4	285.12
Common Shares	Purchase	4	285.79
Common Shares	Purchase	4	280.48
Common Shares	Purchase	4	279.98
Common Shares	Purchase	4	282.53
Common Shares	Purchase	4	279.09
Common Shares	Purchase	4	279.67
Common Shares	Purchase	4	280.75
Common Shares	Purchase	4	282.56
Common Shares	Purchase	5	279.67
Common Shares	Purchase	5	279.92
Common Shares	Purchase	5	279.67
Common Shares	Purchase	5	281.83
Common Shares	Purchase	5	279.67
Common Shares	Purchase	5	280.75
Common Shares	Purchase	5	279.24
Common Shares	Purchase	5	280.75
Common Shares	Purchase	5	279.13
Common Shares	Purchase	5	280.22
Common Shares	Purchase	5	285.78
Common Shares	Purchase	5	283.55
Common Shares	Purchase	5	286.14
Common Shares	Purchase	5	281.99
Common Shares	Purchase	5	281.99
Common Shares	Purchase	5	286.14
Common Shares	Purchase	5	280.75
Common Shares	Purchase	5	279.52
Common Shares	Purchase	5	279.67
Common Shares	Purchase	5	281.36
Common Shares	Purchase	5	281.36
Common Shares	Purchase	5	279.67
Common Shares	Purchase	5	286.14
Common Shares	Purchase	6	283.52
Common Shares	Purchase	6	279.99
Common Shares	Purchase	6	279.99
Common Shares	Purchase	6	280.75
Common Shares	Purchase	6	280.08
Common Shares	Purchase	6	280.44
Common Shares	Purchase	6	280.75
Common Shares	Purchase	6	280.58
Common Shares	Purchase	6	279.68
Common Shares	Purchase	6	285.78
Common Shares	Purchase	6	280
Common Shares	Purchase	6	281.36
Common Shares	Purchase	6	279.99
Common Shares	Purchase	6	279.7
Common Shares	Purchase	6	279.67
Common Shares	Purchase	7	280
Common Shares	Purchase	7	279.95
Common Shares	Purchase	7	282.56
Common Shares	Purchase	7	280.75
Common Shares	Purchase	7	280.06
Common Shares	Purchase	7	279.06
Common Shares	Purchase	7	282.56
Common Shares	Purchase	7	281.13
Common Shares	Purchase	7	280.38
Common Shares	Purchase	7	279.67
Common Shares	Purchase	7	285.98
Common Shares	Purchase	7	284.55
Common Shares	Purchase	7	280.14
Common Shares	Purchase	8	281.47
Common Shares	Purchase	8	280.75
Common Shares	Purchase	8	279.06
Common Shares	Purchase	8	283.58
Common Shares	Purchase	8	279.09
Common Shares	Purchase	8	281.83
Common Shares	Purchase	8	283.84
Common Shares	Purchase	8	283.58
Common Shares	Purchase	8	286.23
Common Shares	Purchase	8	283.58
Common Shares	Purchase	8	281.36
Common Shares	Purchase	8	279.67
Common Shares	Purchase	9	280.75
Common Shares	Purchase	9	280.75
Common Shares	Purchase	9	279.67
Common Shares	Purchase	9	281.36
Common Shares	Purchase	9	281.83
Common Shares	Purchase	9	279.95
Common Shares	Purchase	9	279.99
Common Shares	Purchase	9	279.95
Common Shares	Purchase	9	279.67
Common Shares	Purchase	9	283.58
Common Shares	Purchase	9	279.95
Common Shares	Purchase	9	279.95
Common Shares	Purchase	9	279.54
Common Shares	Purchase	9	279.56
Common Shares	Purchase	9	280.34
Common Shares	Purchase	9	279.57
Common Shares	Purchase	9	279.67
Common Shares	Purchase	9	284.52
Common Shares	Purchase	9	280.45
Common Shares	Purchase	9	281.36
Common Shares	Purchase	9	279.67
Common Shares	Purchase	9	279.67
Common Shares	Purchase	9	281.36
Common Shares	Purchase	10	280.7
Common Shares	Purchase	10	279.27
Common Shares	Purchase	10	283.58
Common Shares	Purchase	10	279.67
Common Shares	Purchase	10	281.83
Common Shares	Purchase	10	280.14
Common Shares	Purchase	10	279.67
Common Shares	Purchase	10	286.25
Common Shares	Purchase	10	283.63
Common Shares	Purchase	11	279.99
Common Shares	Purchase	11	286.24
Common Shares	Purchase	11	279.67
Common Shares	Purchase	11	285.86
Common Shares	Purchase	11	279.67
Common Shares	Purchase	12	281.83
Common Shares	Purchase	12	284.87
Common Shares	Purchase	12	282.01
Common Shares	Purchase	12	279.67
Common Shares	Purchase	12	286.19
Common Shares	Purchase	12	279.95
Common Shares	Purchase	12	280.41
Common Shares	Purchase	12	280.75
Common Shares	Purchase	12	280.43
Common Shares	Purchase	13	280.41
Common Shares	Purchase	13	279.95
Common Shares	Purchase	13	279.67
Common Shares	Purchase	13	280.06
Common Shares	Purchase	14	286.14
Common Shares	Purchase	14	280.44
Common Shares	Purchase	14	279.59
Common Shares	Purchase	14	280.75
Common Shares	Purchase	14	279.95
Common Shares	Purchase	14	280.75
Common Shares	Purchase	14	279.95
Common Shares	Purchase	15	281.79
Common Shares	Purchase	15	279.95
Common Shares	Purchase	15	280.75
Common Shares	Purchase	15	280.44
Common Shares	Purchase	15	286.09
Common Shares	Purchase	15	279.95
Common Shares	Purchase	15	279.82
Common Shares	Purchase	16	280.75
Common Shares	Purchase	16	280.75
Common Shares	Purchase	16	279.09
Common Shares	Purchase	17	281.36
Common Shares	Purchase	17	281.41
Common Shares	Purchase	17	280.75
Common Shares	Purchase	17	285.94
Common Shares	Purchase	17	286.14
Common Shares	Purchase	17	280.06
Common Shares	Purchase	18	279.95
Common Shares	Purchase	18	279.95
Common Shares	Purchase	18	283.69
Common Shares	Purchase	18	279.96
Common Shares	Purchase	18	279.7
Common Shares	Purchase	19	279.67
Common Shares	Purchase	19	279.99
Common Shares	Purchase	20	285.58
Common Shares	Purchase	20	279.95
Common Shares	Purchase	20	279.99
Common Shares	Purchase	20	279.67
Common Shares	Purchase	21	279.95
Common Shares	Purchase	21	285.8
Common Shares	Purchase	21	281.36
Common Shares	Purchase	21	283.52
Common Shares	Purchase	21	281.36
Common Shares	Purchase	22	279.22
Common Shares	Purchase	22	284.06
Common Shares	Purchase	22	282.56
Common Shares	Purchase	23	279.09
Common Shares	Purchase	24	280.06
Common Shares	Purchase	24	279.67
Common Shares	Purchase	25	279.67
Common Shares	Purchase	25	282.87
Common Shares	Purchase	25	286.29
Common Shares	Purchase	25	280.05
Common Shares	Purchase	26	284.9
Common Shares	Purchase	27	283.56
Common Shares	Purchase	28	283.7
Common Shares	Purchase	29	280.42
Common Shares	Purchase	29	279.67
Common Shares	Purchase	29	283.62
Common Shares	Purchase	29	284.06
Common Shares	Purchase	29	280.75
Common Shares	Purchase	30	279.67
Common Shares	Purchase	30	284.65
Common Shares	Purchase	30	284.73
Common Shares	Purchase	31	279.95
Common Shares	Purchase	31	280.14
Common Shares	Purchase	31	279.67
Common Shares	Purchase	31	279.92
Common Shares	Purchase	31	281.36
Common Shares	Purchase	31	279.92
Common Shares	Purchase	35	279.95
Common Shares	Purchase	37	279.67
Common Shares	Purchase	38	284.56
Common Shares	Purchase	40	279.67
Common Shares	Purchase	41	279.69
Common Shares	Purchase	44	282.1
Common Shares	Purchase	45	281.41
Common Shares	Purchase	45	280.75
Common Shares	Purchase	46	284.8
Common Shares	Purchase	47	279.67
Common Shares	Purchase	49	280.14
Common Shares	Purchase	50	279.81
Common Shares	Purchase	51	280.14
Common Shares	Purchase	57	280.75
Common Shares	Purchase	57	281.96
Common Shares	Purchase	57	286.14
Common Shares	Purchase	60	283.55
Common Shares	Purchase	73	279.67
Common Shares	Purchase	75	279.95
Common Shares	Purchase	80	279.65
Common Shares	Purchase	80	279.28
Common Shares	Purchase	85	279.98
Common Shares	Purchase	100	279.43
Common Shares	Purchase	100	283.63
Common Shares	Purchase	100	280.13
Common Shares	Purchase	146	280.34
Common Shares	Purchase	200	280.43
Common Shares	Purchase	667	283.42
Common Shares	Purchase	1	279.68
Common Shares	Purchase	2	280.22
Common Shares	Purchase	370	286.4
Common Shares	Purchase	205	286.4
Common Shares	Purchase	838	286.53

Total Purchase	Total Sale
6616	1856

Ap29

(b) Cash-settled derivative transactions

Class of relevant security	Product description e.g. CFD	Nature of dealing e.g. opening/ closing a long/ short position, increasing/ reducing a long/ short position	Number of reference securities (Note 6)	Price per unit (Note 5)

(i) Writing, selling, purchasing or varying

Class of relevant security	Product description e.g. call option	Writing, purchasing, selling, varying etc.	Number of securities to which option relates (Note 6)	Exercise price per unit	Type e.g. American, European etc.	Expiry date	Option money paid/ received per unit

(ii) Exercise

Class of relevant security	Product description e.g. call option	Exercising/ exercised against	Number of securities	Exercise price per unit (Note 5)

(d) Other dealings (including transactions in respect of new securities) (Note 3)

Class of relevant security	Nature of dealing e.g. subscription, conversion, exercise	Details	Price per unit (if applicable) (Note 5)

Ap30

4. OTHER INFORMATION

(a) Indemnity and other dealing arrangements

Details of any indemnity or option arrangement, or any agreement or understanding, formal or informal, relating to relevant securities which may be an inducement to deal or refrain from dealing entered into by the person making the disclosure and any party to the offer or any person acting in concert with a party to the offer.

Irrevocable commitments and letters of intent should not be included. If there are no such agreements, arrangements or understandings, state "none"

(b) Agreements, arrangements or understandings relating to options or derivatives

Full details of any agreement, arrangement or understanding between the person disclosing and any other person relating to the voting rights of any relevant securities under any option referred to on this form or relating to the voting rights or future acquisition or disposal of any relevant securities to which any derivative referred to on this form is referenced. If none, this should be stated.

Is a Supplemental Form 8 attached?

YES/NO

Date of disclosure	01/12/2022
Contact name	Bukki Osula
Telephone number	+44 (0)2039429419

Public disclosures under Rule 8.3 of the Rules must be made to a Regulatory Information Service.

Ap31

NOTES ON FORM 8.3

1. See the definition of "connected fund manager" in Rule 2.2 of Part A of the Rules.

2. See the definition of "interest in a relevant security" in Rule 2.5 of Part A of the Rules and see Rule 8.6(a) and (b) of Part B of the Rules.

3. See the definition of "relevant securities" in Rule 2.1 of Part A of the Rules.

4. See the definition of "dealing" in Rule 2.1 of Part A of the Rules.

5. If the economic exposure to changes in the price of securities is limited, for example, by virtue of a stop loss arrangement relating to a spread bet, full details must be given.

6. See Rule 2.5(d) of Part A of the Rules.

7. If details included in a disclosure under Rule 8 are incorrect, they should be corrected as soon as practicable in a subsequent disclosure. Such disclosure should state clearly that it corrects details disclosed previously, identify the disclosure or disclosures being corrected, and provide sufficient detail for the reader to understand the nature of the corrections. In the case of any doubt, the Panel should be consulted.

For full details of disclosure requirements, see Rule 8 of the Rules. If in doubt, consult the Panel.

References in these notes to "the Rules" are to the Irish Takeover Panel Act, 1997, Takeover Rules, 2022.

This information is provided by RNS, the news service of the London Stock Exchange. RNS is approved by the Financial Conduct Authority to act as a Primary Information Provider in the United Kingdom. Terms and conditions relating to the use and distribution of this information may apply. For further information, please contact rns@lseg.com or visit www.rns.com.

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END

ISEEADAFESEAFAA

Company Announcements

Form 8.3 - Amgen Inc- Replacement