Global Oncology Innovation Continues Despite Pandemic; Global R&D Pipeline Reached 3,500 New Drugs in 2020, up 75% from 2015, Says New Report from the IQVIA Institute for Human Data Science
17 new cancer medicines launched in the
U.S.in 2020, bringing the total over the past 5 years to 62 innovative therapies, collectively approved for 130 indications across 24 different tumor types
The pandemic continues to have a substantial impact on cancer care with oncologists in the US,
Japanand Europereporting caseloads that are 26% to 51% lower than pre-pandemic levels
Check-point inhibitors first introduced in 2011 have induced responses in some previously intractable cancers and have seen remarkable uptake, almost doubling since 2018 in use per capita in the
U.S., higher than EU4, UKand Japan.
- Access to medicines has been steadily increasing and 9.2 billion Defined Daily Doses (DDDs) were delivered globally in 2020 but variability across countries remains high
Global spending on oncology drugs – using list or invoice prices – reached
$164 billionin 2020; a compound annual growth rate of 14.3% over the past 5 years
“While the pandemic still is having significant impact on cancer care, innovations in oncology continues largely unaffected, reflecting the substantial and sustained commitment to advancing care for patients by oncologists and other care providers, governments and payers, and life sciences companies,” said
A few key highlights of the
Impact of COVID-19 on Cancer Care: The pandemic continues to have a substantial impact on cancer care with oncologists in the
U.S., Japanand Europereporting caseloads that are 26 to 51 percent lower than pre-pandemic levels, delays in necessary treatments, screenings at 11 to 23 percent below baseline levels and community oncologists in the U.S.reporting an increasing share of their new patients presenting with metastatic cancer
- Innovation: The surge of new innovative cancer medicines that began a decade ago continued in 2020 with 17 new drugs being launched and made available – at different times - to patients around the world, especially those with rare cancers
- Research and Development: Scientific breakthroughs in understanding rare cancers that lead to novel therapeutics, and a biomedical eco-system that provides funding and support for R&D especially among emerging biopharma companies, have resulted in a pipeline of almost 3,500 potential cancer treatments, up 75 percent since 2015
- Bringing Scientific Advances to Cancer Patients: Access to medicines has been steadily increasing and 9.2 billion DDDs were delivered globally in 2020, but variability across countries remains high. The use of predictive biomarkers to effectively deliver precision medicines to those who will benefit from them remains variable across cancer types and countries
Spending on Oncology Medicines: The surge in innovation treatments in recent years, strong focus across health systems to increase early diagnosis and expand patient access to treatments, has resulted in global spending on oncology drugs of
$164 billionin 2020, growing to an estimated $269 billionby 2025
The full version of the report, including a detailed description of the methodology, is available at www.IQVIAInstitute.org. The study was produced independently as a public service, without industry or government funding.
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