Takeda’s TAKHZYRO® (lanadelumab-flyo) Prefilled Syringe Now Available for People With Hereditary Angioedema (HAE) Ages 12 Years and Older in the United States
“By introducing TAKHZYRO prefilled syringe to the HAE community, our aim is to continue to enhance the patient experience. With this advancement, those taking TAKHZYRO can now live their life with a ready-to-use option that requires fewer steps and less waste than when using the single-dose vial to receive their injection,” said
With a proven efficacy and safety profile and real-world experience, TAKHZYRO has been available in the
“HAE attacks are unpredictable, debilitating and in some cases life-threatening, adding uncertainty and complexity to the daily lives of those living with this disease and their families,” said Dr.
TAKHZYRO Important Safety Information
TAKHZYRO may cause serious side effects, including allergic reactions. Call your healthcare provider or get emergency help right away if you have any of the following symptoms:
- difficulty breathing
- chest tightness
- fast heartbeat
The most common side effects seen with TAKHZYRO were injection site reactions (pain, redness, and bruising), upper respiratory infection, and headache.
These are not all the possible side effects of TAKHZYRO. For more information, ask your healthcare provider or pharmacist. You may report side effects to the FDA at 1-800-FDA-1088.
TAKHZYRO has not been studied in pregnant or breastfeeding women. Talk to your healthcare provider about the risk of taking TAKHZYRO if you are pregnant, plan to be pregnant, are breastfeeding, or plan to breastfeed.
Please see full Prescribing Information, including information for patients.
About Hereditary Angioedema
HAE is a rare genetic disease that results in recurring attacks of edema – swelling – in various parts of the body, including the abdomen, face, feet, genitals, hands and throat. The swelling can be debilitating and painful.2,3,4 Attacks that obstruct the airways can cause asphyxiation and are potentially life-threatening.4,7 HAE affects an estimated 1 in 50,000 people worldwide.6 It is often under-recognized, under-diagnosed and under-treated.4
Takeda in Hereditary Angioedema
Hereditary Angioedema (HAE), like so many other rare diseases, is highly complex, and patients, their families and caregivers often undergo years of strain trying to understand their disease, get a definitive diagnosis and gain access to the medicines they need. At Takeda we are a committed champion for the patients we serve. Every individual living with HAE is unique and by listening and reacting to their needs, we translate the insights we gain into innovative solutions – from diagnosis to ongoing management. Advancing the science is crucial to the way we operate and we are bold in our mission to accelerate diagnosis and develop treatments that will make a difference to the lives of HAE patients, their support networks and those medical professionals who care for them.
About TAKHZYRO® (lanadelumab-flyo) Injection
TAKHZYRO is a prescription medicine used to prevent attacks of hereditary angioedema (
Takeda is a global, values-based, R&D-driven biopharmaceutical leader headquartered in
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- TAKHZYRO® (lanadelumab-flyo) injection Prescribing Information.
Cicardi M, Bork K, Caballero T, et al; on behalf of HAWK (
Hereditary Angioedema International Working Group). Evidence-based recommendations for the therapeutic management of angioedema owing to hereditary C1 inhibitor deficiency: consensus report of an International Working Group. Allergy. 2012; 67(2):147-157.
- Zuraw BL. Hereditary angioedema. N Engl J Med. 2008;359(10):1027-1036.
- Banerji A. The burden of illness in patients with hereditary angioedema. Ann Allergy Asthma Immunol. 2013;111(5):329-336.
Banerji A, Bernstein JA, Johnston DT, et al. Long-term prevention of hereditary angioedema attacks with lanadelumab: the HELP OLE Study. Allergy. Published online
July 21, 2021. doi:10.1111/all.15011
Busse P, Christiansen S, Riedl M et al.
US HAEA Medical Advisory Board2020 Guidelines for the Management of Hereditary Angioedema. J Allergy Clin Immunol Pract. 2021;9:132-50.
Bork K. Hereditaryangioedema: causes, manifestations, and treatment. Br J Hosp Med. 2006;67(12):654-657.