Antengene to Present Four Preclinical Abstracts at AACR 2024, Highlighting Focus on Cancer Immunology, Targeted Agents and Novel Technology Platforms
- The first preclinical abstract on ATG-O42 (MTAPnull-selective small molecule PRMT5 inhibitor) as well as the latest data on the proprietary T cell engager platform, AnTenGagerTM, and ATG-102 (LILRB4 x CD3 T cell engager).
- The first view of ATG-022 (Claudin 18.2 ADC) companion diagnostic.
"The promising data we are about to present at this year's AACR Annual Meeting underscore
Details of the posters:
ATG-042 (MTAPnull-selective PRMT5 Inhibitor)
Title: Preclinical characterization of ATG-042, a novel MTAPnull-selective PRMT5 inhibitor
Abstract: 4592
Session Category: Experimental and Molecular Therapeutics
Session Title: HDAC and Methyltransferase Inhibitors
Date:
Time:
12:00 AM - 3:30 AM,
Location: Poster Section 24
Companion Diagnostic Antibody for ATG-022 (Claudin 18.2 ADC)
Title: Development of a novel companion diagnostic immunohistochemistry antibody for Claudin 18.2-targeted therapies
Abstract: 1032
Session Category: Clinical Research
Session Title: Diagnostic Biomarkers 1
Date:
Time:
4:30 AM -
Location: Poster Section 42
AnTenGagerTM Platform
Title: AnTenGagerTM, a novel "2+1" T cell engager platform, enables conditional T cell activation with reduced risk of CRS
Abstract: 6343
Session Category: Clinical Research
Session Title: Antibodies 2
Date:
Time:
4:30 AM -
Location: Poster Section 41
ATG-102 (LILRB4 x CD3 T Cell Engager)
Title: ATG-102, a novel LILRB4 x CD3 T cell engager, targeting two non-overlapping epitopes of LILRB4, for the treatment of monocytic AML
Abstract: 2372
Session Category: Clinical Research
Session Title: Antibodies 1
Date:
Time:
12:00 AM - 3:30 AM,
Location: Poster Section 38
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