Endo Launches Spatial Computing Simulator to Create a Fully Immersive Learning Environment for Hand Specialists
- Endo is the first pharmaceutical company to launch an external spatial computing program.
- The Spatial Computing Injection Simulator allows hand specialists to interact simultaneously with both physical and digital objects—blending a physical hand model and digital content via an Apple Vision Pro app—to help refine their injection technique.
- All members of Endo's orthopedics sales team are able to offer the experience to healthcare providers.
Experience the interactive Multimedia News Release here: https://www.multivu.com/endo/9322451-en-endo-launches-spatial-computing-injection-simulator-for-xiaflex
"The Spatial Computing Injection Simulator represents a major leap forward in enhancing patient care through a groundbreaking educational tool," said
Endo designed the Spatial Computing Injection Simulator to help hand specialists refine their injection technique in the hand for the administration of XIAFLEX® (collagenase clostridium histolyticum), the only FDA-approved nonsurgical treatment for Dupuytren's contracture when a "cord" can be felt.
Do not receive XIAFLEX® if you have had an allergic reaction to collagenase clostridium histolyticum or any of the ingredients in XIAFLEX®, or to any other collagenase product.
The Experience
The Spatial Computing Injection Simulator allows providers to interact with both physical objects and digital content simultaneously via a lifelike hand simulator model and an Apple Vision Pro app.
During the immersive, 20-minute experience, hand specialists receive "hands on" practice on reconstitution and injection angles, watch procedures in action, practice their injection technique on the hand model, and acquire information on the post-injection process.
This can help them refine their technique for the treatment of real patients with XIAFLEX, which is injected into the collagen "cord" causing the hand contracture.1
XIAFLEX represents an important treatment option to help appropriate patients.1
Early Reactions and Reviews
Endo recently previewed the technology at two premier medical conferences and generated interest and buzz for the program. At both the
"Technology like this can make a huge difference for a hand surgeon or advanced practice provider in treating Dupuytren's contracture nonsurgically," said Dr.
Now, all members of Endo's orthopedics sales team are able to offer the experience to healthcare providers.
Endo worked with technology agency Lucid Dream to create the Apple Vision Pro app and spatial computing experience.
About Dupuytren's Contracture
Dupuytren's contracture is a lifelong condition that may get worse over time. It's caused by a buildup of collagen in the hand, which forms a rope-like cord that pulls fingers toward the palm so they can't be straightened. As Dupuytren's contracture progresses, it may become difficult for individuals to use their hand(s) for daily tasks and activities.2,3 Dupuytren's contracture affects an estimated 17 million Americans.4,5*
WHAT IS XIAFLEX®?
XIAFLEX is a prescription medicine used to treat adults with Dupuytren's contracture when a "cord" can be felt. It is not known if XIAFLEX is safe and effective in children under the age of 18.
IMPORTANT SAFETY INFORMATION FOR XIAFLEX
Do not receive XIAFLEX if you have had an allergic reaction to collagenase clostridium histolyticum or any of the ingredients in XIAFLEX, or to any other collagenase product. See the end of the Medication Guide for a complete list of ingredients in XIAFLEX.
XIAFLEX can cause serious side effects, including:
- Tendon rupture or ligament damage. Receiving an injection of XIAFLEX may cause damage to a tendon or ligament in your hand and cause it to break or weaken. This could require surgery to fix the damaged tendon or ligament. Call your healthcare provider right away if you have trouble bending your injected finger (towards the wrist) after the swelling goes down or you have problems using your treated hand after your follow-up visit
- Nerve injury or other serious injury of the hand. After finger procedures, some people developed tears in the skin (lacerations), and local skin and soft-tissue necrosis (death of skin cells). Some lacerations and necrosis required skin grafting, or other surgery including amputation. Call your healthcare provider right away if you get numbness, tingling, increased pain, or tears in the skin (laceration) in your treated finger or hand after your injection or after your follow-up visit
- Hypersensitivity reactions, including anaphylaxis. Severe allergic reactions can happen in people who receive XIAFLEX because it contains foreign proteins. Call your healthcare provider right away if you have any of these symptoms of an allergic reaction after an injection of XIAFLEX:
- hives
- swollen face
- breathing trouble
- chest pain
- low blood pressure
- dizziness or fainting
-
Fainting. Fainting (passing out) or near fainting can happen in people who receive XIAFLEX, especially following finger procedures
If you have dizziness or feel faint after receiving XIAFLEX, lie down until the symptoms go away. - Increased chance of bleeding. Bleeding or bruising at the injection site can happen in people who receive XIAFLEX. Talk to your healthcare provider if you have a problem with your blood clotting. XIAFLEX may not be right for you.
Before receiving XIAFLEX, tell your healthcare provider if you have had an allergic reaction to a previous XIAFLEX injection, or have a bleeding problem or any other medical conditions. Tell your healthcare provider about all the medicines you take, including prescription and non-prescription medicines, vitamins, and herbal supplements. Using XIAFLEX with certain other medicines can cause serious side effects. Especially tell your healthcare provider if you take medicines to thin your blood (anticoagulants). If you are told to stop taking a blood thinner before your XIAFLEX injection, your healthcare provider should tell you when to restart the blood thinner. Ask your healthcare provider or pharmacist for a list of these medicines if you are unsure.
The most common side effects with XIAFLEX for the treatment of Dupuytren's contracture include:
- swelling of the injection site or the hand
- bruising or bleeding at the injection site
- pain or tenderness of the injection site or the hand
- swelling of the lymph nodes (glands) in the elbow or armpit
- itching
- breaks in the skin
- redness or warmth of the skin
- pain in the armpit
Tell your healthcare provider if you have any side effect that bothers you or does not go away. These are not all of the possible side effects with XIAFLEX. For more information, ask your healthcare provider or pharmacist.
Rx Only
Click for full Prescribing Information, including Medication Guide.
About Endo
Endo is a diversified specialty pharmaceutical company boldly transforming insights into life-enhancing therapies. Our passionate team members collaborate to develop and deliver these essential medicines. Together, we are committed to helping everyone we serve live their best life. Learn more at www.endo.com or connect with us on LinkedIn.
Cautionary Note Regarding Forward-Looking Statements
This press release contains forward-looking statements including, but not limited to, the statements by
*Dupuytren's contracture prevalence estimation calculation: average Dupuytren's contracture prevalence in the US (5%) multiplied by US population (332 million per 2021 US Census data) = ~17 million.
References
- XIAFLEX® [Prescribing Information].
Rochester, MI :Endo USA, Inc. - Hurst LC, Badalamente MA, Hentz VR, et al. N Engl J Med. 2009;361(10),968-979.
- Bayat A, McGrouther DA. Management of Dupuytren's disease--clear advice for an elusive condition. Ann R Coll
Surg Engl . 2006;88(1):3-8. - "How common is Dupuytren disease?"
Dupuytren Research Group .April 1, 2017 . AccessedJanuary 13, 2025 . https://dupuytrens.org/faq - "
U.S. and world population clock."U.S. Census Bureau . UpdatedApril 13, 2023 . AccessedJanuary 13, 2025 . https://www.census.gov/popclock


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