DuPont Expands Bioprocessing Portfolio with Launch of DuPont™ AmberChrom™ TQ1 Chromatography Resin
Agarose-based chromatography resin supports purification of oligonucleotides and peptides for biopharma applications
"The introduction of DuPont™ AmberChrom™ TQ1 chromatography resin supports the accelerated development and commercialization of oligonucleotide and peptide therapeutics," said
The new agarose-based chromatography resin offers increased loading capacity, higher throughput, and requires less pressure than comparable competing products within the same class. These characteristics make DuPont™ AmberChrom™ TQ1 chromatography resin an excellent choice for high resolution separations and polishing, offering high purity fractions in biomolecule purifications and the separation of closely-related impurities from target molecules. Its low-pressure build-up, combined with high-yield and purity for peptides and both DMT-Off and DMT-On oligonucleotides, makes the resin suitable for use in benchtop and large-scale commercial purifications.
To support the introduction of the resin, DuPont has published comprehensive internal application studies that used real-world drug feeds to validate performance characteristics; this documentation can also assist with the integration of the product into processes at every phase from drug discovery through commercialization.
"Further expansion of DuPont's bioprocessing portfolio reflects our commitment to providing a comprehensive one-stop shop for the purification and polishing of oligonucleotides and peptides," said Kendra. "Our technical teams and scientists are continually collaborating with customers to design efficient bioprocessing solutions for every stage of the drug development journey."
DuPont™ AmberChrom™ TQ1 chromatography resin can be used in combination with existing AmberChrom™ XT and CG chromatography resins to purify various oligonucleotide feeds, or for the crude purification of peptide feeds in preparation for reverse phase chromatography.
DuPont introduced the new chromatography resin to the market during TIDES USA—a conference dedicated to accelerating oligonucleotide and peptide innovations.
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Learn more about DuPont™ AmberChrom™ TQ1 chromatography resin and the broader DuPont bioprocessing portfolio.
As a global market leader in adsorbents and ion exchange resins with over 80 years of experience, DuPont bioprocessing solutions can accelerate and enhance the discovery and production of small molecule synthetics, oligonucleotides, and peptides, as well as diagnostics, by enabling complicated separations that help companies achieve their vision to manage and treat diseases.
About DuPont
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