Elsevier expands ClinicalKey AI with unrivaled full-text knowledge base and technology upgrades to help clinicians make decisions with confidence
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ClinicalKey AI now includes full-text content from premium journals and medical organizations such as
The Lancet , theNew England Journal of Medicine (NEJM), the European Society For Medical Oncology and theAmerican College of Cardiology , offering the broadest collection of trusted medical evidence-based content in a clinical AI solution - Technology enhancements support HIPAA compliance and provide clinicians and healthcare institutions with added security and transparency while using the solution
Clinicians are under growing strain as they work in an increasingly pressurized environment with significant capacity challenges, and while AI can address these challenges, the rapid growth of AI solutions has led to concerns about their reliability and security. AI use in healthcare doubled in 2025, but only 40% of clinicians trusted it* – the question is no longer "can AI help clinicians?", but "can clinicians trust AI?"
ClinicalKey AI addresses these concerns by building confidence, competence, and curiosity grounded in trust. Its expanded content set is complemented by new real-time verification steps to drive accuracy, as clinicians can trace the exact evidence that was used to create an answer. The new unmatched "traceability" of ClinicalKey AI's answers provides transparency and reassurance for clinicians, building their confidence when using the tool at the point of care. Responses are traced not just to a paper or a textbook, but to the exact paragraph it was cited from.
Credibility is further enhanced by ClinicalKey AI's "clinician-in-the-loop" approach, with a rigorous evaluation framework to ensure highest quality insights.
ClinicalKey AI now includes full-text content and clinical practice guidelines from leading medical journals and organizations – clinicians can access copyright-cleared answers on ClinicalKey AI based on peer-reviewed full-text articles from more than 1,000 medical journals. ClinicalKey AI content is updated every 24 hours, so clinicians know they are accessing the most current information and guidelines. ClinicalKey AI turns this verified content into structured and linked data, so the answers are more precise, relevant and useful in real-world settings.
Already in use in over 300 hospitals across the world, ClinicalKey AI's expanded content includes:
- Increasing the number of curated full-text premium journals indexed to more than 130 (including
The Lancet series,New England Journal of Medicine , Chest,Journal of Allergy and Clinical Immunology ,Journal of Thoracic Oncology , andAmerican Journal of Obstetrics and Gynecology ) with many more being added in the coming weeks. - Full-text coverage adds clinical practice guidelines from leading organizations, including the
American College of Cardiology , theAmerican Association of Clinical Endocrinology , the European Society For Medical Oncology, theAmerican College of Emergency Physicians , theAmerican Gastroenterological Association and many more.
Dr.
ClinicalKey AI is now even simpler to access, with additional new features including:
- API-based integration options, including compatibility with workflow tools.
- An upgraded user experience, including a streamlined interface, improved navigation, native voice-to-text dictation in the mobile app, query history controls via a privacy panel, and easy toggling between adult and pediatric contexts.
- Supportive of HIPAA-compliant use, with privacy and security controls built to help protect patient health information (PHI).
- A reading assistant that supports learning and curiosity by allowing clinicians to explore and engage with full text articles (coming in March).
- Multi-language support and prompt sharing.
You can find out more about ClinicalKey AI here.
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