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About the company
Day One Biopharmaceuticals, Inc. is a commercial-stage biopharmaceutical company focused on developing and commercializing targeted therapies for people of all ages with life-threatening diseases. It partners with clinical oncologists, families, and scientists to identify, acquire, and develop cancer treatments. Its commercial product, OJEMDA (tovorafenib), is an oral, brain-penetrant, selective type II rapidly accelerated fibrosarcoma (RAF) kinase inhibitor. OJEMDA is used for the treatment of patients over six months of age and older with relapsed or refractory pLGG harboring a BRAF fusion or rearrangement, or BRAF V600 mutation. Its pipeline product candidates include DAY301 and Emi-Le (emiltatug ledadotin). DAY301 is a novel Antibody Drug Conjugate, or ADC, targeting protein-tyrosine kinase 7, or PTK7. Emi-Le (emiltatug ledadotin) is a novel antibody drug conjugate (ADC) targeting the B7-H4 protein in clinical development to treat the rare cancer adenoid cystic carcinoma (ACC).
- Revenue in USD (TTM)133.67m
- Net income in USD-151.76m
- Incorporated2018
- Employees184.00
- LocationDay One Biopharmaceuticals Inc1800 Sierra Point Parkway, Suite 200BRISBANE 94005United StatesUSA
- Phone+1 (650) 484-0899
- Fax+1 (302) 636-5454
- Websitehttps://dayonebio.com/
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Mergers & acquisitions
| Acquired company | DAWN:NSQ since announced | Transaction value |
|---|---|---|
| Mersana Therapeutics Inc | 9.77% | 282.14m |
Data delayed at least 15 minutes, as of Feb 13 2026 21:00 GMT.
Peer analysis
Key Information
- Key Information
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- Per Share Data
- Efficiency
- Management Effectiveness
- Profitability
- Financial Strength
- Growth Rates
| Company | Revenue (TTM) | Net income (TTM) | Market cap | Employees | Price/earnings (TTM) | Price/book value (MRQ) | Price/cash flow (TTM) | Price/sales (TTM) | EPS (excl. extraordinary items, TTM) | EPS (incl. extraordinary items, TTM) | Revenue per share (TTM) | Book value per share (MRQ) | Asset turnover (TTM) | Inventory turnover (TTM) | Receivables turnover (TTM) | Revenues per employee (TTM) | Return on avg assets (TTM) | Return on avg assets (5 yr avg) | Return on investment (TTM) | Return on investment (5 yr avg) | Gross margin (TTM) | Gross margin (5 yr avg) | Net profit margin (TTM) | Net Profit margin (5 yr avg) | Quick ratio (MRQ) | Interest coverage (TTM) | Total debt to capital (MRQ) | Payout ratio (5 yr avg) | Revenue (YOY change %) | Revenue (5 yr growth rate) | Net income (YOY change %) | Net income (5 yr growth rate) | Capital expenditure (5 yr growth rate) | Dividend (5 yr growth rate) |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ASP Isotopes Inc | 8.38m | -105.56m | 653.07m | 136.00 | -- | 6.58 | -- | 77.90 | -1.43 | -1.43 | 0.1124 | 0.7932 | 0.0541 | 8.86 | 0.884 | 61,642.43 | -68.21 | -- | -85.13 | -- | 23.00 | -- | -1,261.23 | -- | 6.10 | -0.6787 | 0.5382 | -- | 857.03 | -- | -115.60 | -- | -- | -- |
| Ironwood Pharmaceuticals, Inc. | 338.99m | 28.55m | 732.05m | 253.00 | 32.04 | -- | 24.04 | 2.16 | 0.1404 | 0.1404 | 2.00 | -1.62 | 0.863 | -- | 3.45 | 1,339,870.00 | 7.27 | -6.08 | 11.57 | -7.13 | -- | -- | 8.42 | -11.01 | -- | 4.73 | 1.82 | -- | -20.63 | -3.89 | 100.09 | -56.87 | -54.38 | -- |
| Nika Pharmaceuticals Inc | 0.00 | -51.76k | 785.60m | -- | -- | -- | -- | -- | -0.00005 | -0.00005 | 0.00 | -0.0003 | 0.00 | -- | -- | -- | -413.75 | -21,428.06 | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -47.74 | -- | -- | -- |
| Esperion Therapeutics Inc | 303.80m | -105.83m | 819.99m | 304.00 | -- | -- | -- | 2.70 | -0.5358 | -0.5358 | 1.54 | -2.20 | 0.896 | 1.35 | 3.25 | 999,348.70 | -31.21 | -61.82 | -138.14 | -101.31 | 58.20 | 81.27 | -34.84 | -109.30 | 0.7017 | -0.3928 | 4.08 | -- | 185.66 | 17.50 | 75.27 | -- | -19.76 | -- |
| Pacira Biosciences Inc | 716.79m | 21.44m | 894.75m | 790.00 | 46.68 | 1.29 | 7.96 | 1.25 | 0.4664 | 0.4664 | 15.70 | 16.93 | 0.5085 | 1.11 | 6.64 | 907,330.40 | 1.52 | 1.87 | 1.78 | 2.22 | 79.17 | 73.06 | 2.99 | 4.84 | 3.78 | -- | 0.3413 | 0.00 | 3.85 | 10.73 | -337.30 | -- | 0.9219 | -- |
| Phathom Pharmaceuticals Inc | 147.19m | -274.55m | 936.58m | 427.00 | -- | -- | -- | 6.36 | -3.81 | -3.81 | 2.04 | -5.95 | 0.4693 | 5.58 | 3.83 | 344,707.30 | -87.53 | -72.89 | -117.10 | -84.11 | 87.25 | -- | -186.53 | -1,799.61 | 2.19 | -3.35 | 3.68 | -- | 8,001.47 | -- | -65.84 | -- | 0.4505 | -- |
| Theravance Biopharma Inc | 80.33m | 29.34m | 989.63m | 97.00 | 34.71 | 4.25 | 31.93 | 12.32 | 0.5626 | 0.5626 | 1.59 | 4.59 | 0.2082 | -- | 4.58 | 828,113.40 | 7.61 | -34.51 | 8.26 | -40.08 | -- | -- | 36.53 | -254.51 | -- | -- | 0.1216 | -- | 12.12 | -2.59 | -2.22 | -- | -36.34 | -- |
| EyePoint Inc | 42.34m | -205.75m | 1.07bn | 165.00 | -- | 4.50 | -- | 25.30 | -2.99 | -2.99 | 0.617 | 2.88 | 0.1532 | 1.02 | 59.51 | 256,606.10 | -74.47 | -35.88 | -86.87 | -42.05 | 94.08 | 84.82 | -485.95 | -201.78 | 7.11 | -- | 0.00 | -- | -5.97 | 16.27 | -84.86 | -- | 80.24 | -- |
| Xeris Biopharma Holdings Inc | 266.14m | -15.64m | 1.13bn | 394.00 | -- | -- | -- | 4.25 | -0.1033 | -0.1033 | 1.67 | -0.0052 | 0.77 | 0.7301 | 5.61 | 675,474.60 | -4.52 | -31.61 | -6.46 | -42.28 | 84.56 | 79.76 | -5.88 | -77.77 | 1.35 | 0.3853 | 1.00 | -- | 23.89 | 136.89 | 11.92 | -- | -4.75 | -- |
| Day One Biopharmaceuticals Inc | 133.67m | -151.76m | 1.17bn | 184.00 | -- | 2.58 | -- | 8.72 | -1.48 | -1.48 | 1.30 | 4.39 | 0.2399 | 2.88 | 10.53 | 738,519.30 | -27.23 | -39.78 | -29.80 | -43.02 | 89.44 | -- | -113.53 | -414.14 | 8.55 | -- | 0.00 | -- | -- | -- | 49.45 | -- | -- | -- |
| Amphastar Pharmaceuticals Inc | 723.31m | 111.63m | 1.31bn | 2.03k | 12.64 | 1.70 | 7.82 | 1.81 | 2.26 | 2.26 | 14.69 | 16.76 | 0.4505 | 2.32 | 5.05 | 356,659.30 | 6.95 | 9.84 | 7.84 | 11.71 | 49.36 | 49.55 | 15.43 | 17.15 | 2.21 | 8.96 | 0.4397 | 0.00 | 13.59 | 17.82 | 15.98 | 26.66 | -0.2486 | -- |
| Collegium Pharmaceutical Inc | 757.07m | 58.44m | 1.45bn | 357.00 | 28.56 | 5.27 | 5.09 | 1.91 | 1.60 | 1.60 | 19.94 | 8.70 | 0.467 | 8.51 | 3.27 | 2,120,636.00 | 3.60 | 4.11 | 5.02 | 6.64 | 57.22 | 55.50 | 7.72 | 8.48 | 1.27 | 2.23 | 0.7462 | 0.00 | 11.41 | 16.31 | 43.68 | -- | -23.82 | -- |
| Veradermics Inc | 0.00 | -53.81m | 1.62bn | 19.00 | -- | -- | -- | -- | -1.53 | -1.53 | 0.00 | 0.3731 | -- | -- | -- | 0.00 | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | 0.00 | -- | -- | -- | -60.63 | -- | -- | -- |
| Immunocore Holdings PLC - ADR | 379.59m | -29.23m | 1.63bn | 493.00 | -- | -- | -- | 4.30 | -0.5866 | -0.5866 | 7.49 | -- | 0.3471 | 0.5336 | 5.44 | 769,959.40 | -2.67 | -17.90 | -3.34 | -23.26 | 99.29 | -- | -7.70 | -53.74 | 5.97 | -- | 0.4975 | -- | 24.37 | 56.77 | 7.60 | -- | -1.06 | -- |
Data as of Feb 13 2026. Currency figures normalised to Day One Biopharmaceuticals Inc's reporting currency: US Dollar USD
36.39%Per cent of shares held by top holders
| Holder | Shares | % Held |
|---|---|---|
| Fidelity Management & Research Co. LLCas of 30 Sep 2025 | 7.60m | 7.19% |
| BlackRock Fund Advisorsas of 31 Dec 2025 | 6.65m | 6.29% |
| The Vanguard Group, Inc.as of 31 Dec 2025 | 5.72m | 5.41% |
| SSgA Funds Management, Inc.as of 31 Dec 2025 | 4.29m | 4.06% |
| Pictet Asset Management SAas of 31 Dec 2025 | 2.99m | 2.83% |
| Vestal Point Capital LPas of 30 Sep 2025 | 2.68m | 2.53% |
| FIAM LLCas of 30 Sep 2025 | 2.49m | 2.36% |
| Braidwell LPas of 30 Sep 2025 | 2.18m | 2.06% |
| AIGH Capital Management LLCas of 31 Dec 2025 | 1.99m | 1.89% |
| Geode Capital Management LLCas of 31 Dec 2025 | 1.88m | 1.78% |
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Data from 30 Sep 2025 - 31 Dec 2025Source: FactSet Research Systems Inc.
