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About the company
Fulcrum Therapeutics, Inc. is a clinical-stage biopharmaceutical company. The Company is focused on improving the lives of patients with genetically defined rare diseases in areas of high unmet medical need. The Company’s clinical product candidate, losmapimod, is developed for the potential treatment of facioscapulohumeral muscular dystrophy (FSHD). Its other clinical product candidate is FTX-6058, which is developed for the treatment of certain hemoglobinopathies, including sickle cell disease (SCD). In addition to product candidate development, the Company has developed a drug discovery approach that it employs to systematically identify and validate cellular drug targets that can potentially modulate gene expression to treat known root causes of genetically defined rare diseases. The Company has developed pociredir, which is designed to elevate the level of fetal hemoglobin, or HbF, for the treatment of people with SCD.
- Revenue in USD (TTM)80.87m
- Net income in USD-17.91m
- Incorporated2015
- Employees76.00
- LocationFulcrum Therapeutics Inc26 Landsdowne StreetCAMBRIDGE 02139United StatesUSA
- Phone+1 (617) 651-8851
- Fax+1 (302) 655-5049
- Websitehttps://www.fulcrumtx.com/
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Peer analysis
Key Information
- Key Information
- Stock Performance
- Per Share Data
- Efficiency
- Management Effectiveness
- Profitability
- Financial Strength
- Growth Rates
| Company | Revenue (TTM) | Net income (TTM) | Market cap | Employees | Price/earnings (TTM) | Price/book value (MRQ) | Price/cash flow (TTM) | Price/sales (TTM) | EPS (excl. extraordinary items, TTM) | EPS (incl. extraordinary items, TTM) | Revenue per share (TTM) | Book value per share (MRQ) | Asset turnover (TTM) | Inventory turnover (TTM) | Receivables turnover (TTM) | Revenues per employee (TTM) | Return on avg assets (TTM) | Return on avg assets (5 yr avg) | Return on investment (TTM) | Return on investment (5 yr avg) | Gross margin (TTM) | Gross margin (5 yr avg) | Net profit margin (TTM) | Net Profit margin (5 yr avg) | Quick ratio (MRQ) | Interest coverage (TTM) | Total debt to capital (MRQ) | Payout ratio (5 yr avg) | Revenue (YOY change %) | Revenue (5 yr growth rate) | Net income (YOY change %) | Net income (5 yr growth rate) | Capital expenditure (5 yr growth rate) | Dividend (5 yr growth rate) |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Galectin Therapeutics Inc | 0.00 | -45.23m | 175.31m | 14.00 | -- | -- | -- | -- | -0.7284 | -0.7284 | 0.00 | -1.48 | 0.00 | -- | -- | 0.00 | -176.31 | -92.08 | -587.13 | -121.97 | -- | -- | -- | -- | -- | -7.18 | 8.66 | -- | -- | -- | -15.26 | -- | -- | -- |
| Tenaya Therapeutics Inc | 0.00 | -117.23m | 175.87m | 140.00 | -- | 1.56 | -- | -- | -1.44 | -1.44 | 0.00 | 1.42 | 0.00 | -- | -- | 0.00 | -70.20 | -- | -78.56 | -- | -- | -- | -- | -- | -- | -- | 0.00 | -- | -- | -- | -0.3388 | -- | -- | -- |
| Nkarta Inc | 0.00 | -110.61m | 176.42m | 159.00 | -- | 0.4095 | -- | -- | -1.87 | -1.87 | 0.00 | 6.11 | 0.00 | -- | -- | 0.00 | -23.59 | -32.39 | -24.86 | -34.05 | -- | -- | -- | -372,519.20 | -- | -- | 0.00 | -- | -- | -- | -3.22 | -- | 106.05 | -- |
| Caribou Biosciences Inc | 11.48m | -148.12m | 177.48m | 158.00 | -- | 0.6312 | -- | 15.47 | -1.65 | -1.65 | 0.128 | 3.11 | 0.0286 | -- | 5.08 | 72,626.59 | -36.94 | -- | -39.76 | -- | -- | -- | -1,290.81 | -- | -- | -1,321.46 | 0.00 | -- | 148.91 | -- | -2.66 | -- | -- | -- |
| Kyverna Therapeutics Inc | 0.00 | -110.66m | 177.77m | 119.00 | -- | 0.5875 | -- | -- | -2.50 | -2.50 | 0.00 | 7.01 | 0.00 | -- | -- | 0.00 | -51.27 | -- | -57.66 | -- | -- | -- | -- | -- | -- | -- | 0.0038 | -- | -100.00 | -- | -108.93 | -- | -- | -- |
| Inozyme Pharma Inc | 0.00 | -96.49m | 179.23m | 59.00 | -- | 2.16 | -- | -- | -1.55 | -1.55 | 0.00 | 1.29 | 0.00 | -- | -- | 0.00 | -55.29 | -45.00 | -60.60 | -48.90 | -- | -- | -- | -- | -- | -- | 0.3554 | -- | -- | -- | -6.13 | -- | 2.85 | -- |
| Nektar Therapeutics | 93.14m | -168.30m | 184.46m | 137.00 | -- | 3.77 | -- | 1.98 | -0.8371 | -0.8371 | 0.4634 | 0.265 | 0.2483 | 3.96 | 84.52 | 679,832.10 | -44.87 | -31.02 | -53.39 | -34.63 | 67.80 | 78.04 | -180.70 | -372.21 | 4.24 | -15.53 | 0.00 | -- | -2.10 | -40.35 | 25.03 | -- | -42.89 | -- |
| Fulcrum Therapeutics Inc | 80.87m | -17.91m | 186.58m | 76.00 | -- | 0.6268 | -- | 2.31 | -0.3098 | -0.3098 | 1.29 | 4.77 | 0.2899 | -- | 23.41 | 1,064,092.00 | -6.42 | -50.55 | -6.77 | -55.91 | -- | -- | -22.15 | -1,189.10 | -- | -- | 0.00 | -- | -55.77 | -- | 11.41 | -- | -43.70 | -- |
| Compass Therapeutics Inc. | 850.00k | -47.76m | 188.50m | 32.00 | -- | 1.36 | -- | 221.76 | -0.3553 | -0.3553 | 0.0063 | 1.01 | 0.0053 | -- | -- | 26,562.50 | -29.93 | -41.75 | -31.25 | -46.41 | -- | -- | -5,618.71 | -- | -- | -- | 0.00 | -- | -- | -- | -8.33 | -- | -56.91 | -- |
| Zura Bio Ltd | 0.00 | -42.62m | 189.35m | 14.00 | -- | 1.24 | -- | -- | -0.5807 | -0.5807 | 0.00 | 2.34 | 0.00 | -- | -- | 0.00 | -32.18 | -- | -43.31 | -- | -- | -- | -- | -- | -- | -- | 0.00 | -- | -- | -- | -2,050.99 | -- | -- | -- |
| ADC Therapeutics SA | 70.72m | -212.15m | 191.45m | 273.00 | -- | -- | -- | 2.71 | -2.40 | -2.40 | 0.7742 | -1.78 | 0.1733 | 0.2987 | 3.13 | 259,036.60 | -51.13 | -48.41 | -62.27 | -55.63 | 91.81 | -- | -295.00 | -308.62 | 4.68 | -3.92 | 1.65 | -- | -66.86 | 127.56 | -52.78 | -- | 5.42 | -- |
| Enanta Pharmaceuticals Inc | 71.96m | -115.33m | 192.39m | 145.00 | -- | 1.29 | -- | 2.67 | -5.46 | -5.46 | 3.41 | 7.03 | 0.161 | -- | 5.32 | 496,275.90 | -25.80 | -14.56 | -30.05 | -15.62 | -- | -- | -160.27 | -54.96 | -- | -- | 0.0095 | -- | -8.07 | -17.45 | -9.91 | -- | 24.89 | -- |
| Corbus Pharmaceuticals Holdings Inc | 0.00 | -38.70m | 195.85m | 19.00 | -- | 1.30 | -- | -- | -4.69 | -4.69 | 0.00 | 12.36 | 0.00 | -- | -- | 0.00 | -38.61 | -86.84 | -49.21 | -130.46 | -- | -- | -- | -769.76 | -- | -- | 0.00 | -- | -- | -- | -5.33 | -- | -- | -- |
| XBiotech Inc | 0.00 | -32.66m | 197.71m | 92.00 | -- | 1.03 | -- | -- | -1.07 | -1.07 | 0.00 | 6.30 | 0.00 | -- | -- | 0.00 | -14.86 | 31.88 | -15.62 | 33.27 | -- | -- | -- | 877.30 | -- | -- | 0.0495 | 0.00 | -100.00 | -- | 25.36 | -- | 24.30 | -- |
| Quantum-Si Inc | 2.27m | -89.93m | 197.88m | 159.00 | -- | 0.9423 | -- | 87.33 | -0.6334 | -0.6334 | 0.016 | 1.48 | 0.0082 | 0.3423 | 3.05 | 14,251.57 | -32.43 | -- | -34.05 | -- | 51.54 | -- | -3,968.84 | -- | 13.15 | -- | 0.00 | -- | -- | -- | 27.55 | -- | -- | -- |
Data as of Nov 21 2024. Currency figures normalised to Fulcrum Therapeutics Inc's reporting currency: US Dollar USD
51.64%Per cent of shares held by top holders
| Holder | Shares | % Held |
|---|---|---|
| RA Capital Management LPas of 30 Sep 2024 | 10.23m | 16.39% |
| BlackRock Fund Advisorsas of 30 Sep 2024 | 4.82m | 7.72% |
| Nantahala Capital Management LLCas of 30 Sep 2024 | 4.78m | 7.66% |
| The Vanguard Group, Inc.as of 30 Sep 2024 | 3.20m | 5.12% |
| Adage Capital Management LPas of 30 Sep 2024 | 2.00m | 3.21% |
| Fidelity Management & Research Co. LLCas of 30 Sep 2024 | 1.72m | 2.76% |
| SSgA Funds Management, Inc.as of 30 Sep 2024 | 1.68m | 2.69% |
| Geode Capital Management LLCas of 30 Sep 2024 | 1.32m | 2.12% |
| Dimensional Fund Advisors LPas of 30 Sep 2024 | 1.29m | 2.07% |
| Suvretta Capital Management LLCas of 30 Sep 2024 | 1.18m | 1.90% |
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Data from 30 Sep 2024 - 30 Sep 2024Source: FactSet Research Systems Inc.
