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About the company
Orchestra BioMed Holdings, Inc. is a biomedical innovation company. The Company’s lead product candidates include Atrioventricular Interval Modulation (AVIM) therapy for the treatment of hypertension (HTN), the leading risk factor for death worldwide and the Virtue Sirolimus AngioInfusion Balloon (Virtue SAB) for the treatment of atherosclerotic artery disease, the leading cause of mortality worldwide. The Company develops bioelectronic therapies based on patented Cardiac Neuromodulation Therapy (CNT) technology. The AVIM is a bioelectronic therapy candidate designed to substantially and persistently lower blood pressure. Its Virtue SAB is a proprietary drug/device combination product candidate for the treatment of artery disease that is designed to deliver a proprietary, investigational, extended-release formulation of sirolimus (SirolimusEFR) to the vessel wall during balloon angioplasty without the need for balloon coating or a permanent implant.
- Revenue in USD (TTM)2.82m
- Net income in USD-75.10m
- Incorporated2023
- Employees70.00
- LocationOrchestra Biomed Holdings Inc150 Union Square DriveNEW HOPE 18938United StatesUSA
- Phone+1 (646) 343-9298
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Key Information
- Key Information
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- Per Share Data
- Efficiency
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- Financial Strength
- Growth Rates
| Company | Revenue (TTM) | Net income (TTM) | Market cap | Employees | Price/earnings (TTM) | Price/book value (MRQ) | Price/cash flow (TTM) | Price/sales (TTM) | EPS (excl. extraordinary items, TTM) | EPS (incl. extraordinary items, TTM) | Revenue per share (TTM) | Book value per share (MRQ) | Asset turnover (TTM) | Inventory turnover (TTM) | Receivables turnover (TTM) | Revenues per employee (TTM) | Return on avg assets (TTM) | Return on avg assets (5 yr avg) | Return on investment (TTM) | Return on investment (5 yr avg) | Gross margin (TTM) | Gross margin (5 yr avg) | Net profit margin (TTM) | Net Profit margin (5 yr avg) | Quick ratio (MRQ) | Interest coverage (TTM) | Total debt to capital (MRQ) | Payout ratio (5 yr avg) | Revenue (YOY change %) | Revenue (5 yr growth rate) | Net income (YOY change %) | Net income (5 yr growth rate) | Capital expenditure (5 yr growth rate) | Dividend (5 yr growth rate) |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Lucid Diagnostics Inc | 4.40m | -65.84m | 168.89m | 72.00 | -- | -- | -- | 38.39 | -0.8968 | -0.8968 | 0.0526 | 0.1973 | 0.1161 | 12.24 | 14.94 | 61,097.22 | -140.60 | -139.37 | -301.55 | -297.39 | -58.13 | -- | -1,211.30 | -2,492.79 | 1.88 | -- | 0.4633 | -- | 79.00 | -- | -0.6817 | -- | -- | -- |
| Edap Tms SA (ADR) | 75.62m | -23.27m | 174.29m | 310.00 | -- | 6.31 | -- | 2.30 | -0.6214 | -0.6214 | 2.02 | 0.7393 | 0.9081 | 2.08 | 3.62 | 243,930.40 | -27.94 | -11.18 | -49.24 | -15.86 | 43.24 | 42.19 | -30.77 | -16.63 | 0.9729 | -- | 0.2062 | -- | 6.11 | 7.38 | 10.20 | -- | 55.92 | -- |
| Rapid Micro Biosystems Inc | 30.52m | -44.29m | 174.63m | 163.00 | -- | 3.94 | -- | 5.72 | -0.9984 | -0.9984 | 0.6884 | 1.00 | 0.3209 | 1.33 | 6.40 | 187,257.70 | -46.56 | -38.13 | -56.14 | -43.36 | 7.72 | -27.98 | -145.11 | -253.02 | 2.95 | -- | 0.3003 | -- | 24.57 | 11.18 | 10.63 | -- | -4.24 | -- |
| Accendra Health Inc | 6.71bn | -410.53m | 180.99m | 13.50k | -- | -- | -- | 0.027 | -5.33 | -17.41 | 86.97 | -5.56 | 1.47 | 7.59 | 15.52 | 496,837.20 | -9.01 | -0.3346 | -17.40 | -0.5248 | 26.13 | 18.20 | -6.12 | -0.146 | 0.8386 | 1.67 | 1.25 | -- | 3.55 | 3.04 | -778.15 | -- | 34.30 | -- |
| Stereotaxis Inc | 30.07m | -24.91m | 194.12m | 139.00 | -- | 30.24 | -- | 6.45 | -0.281 | -0.281 | 0.3393 | 0.1266 | 0.6232 | 1.47 | 4.54 | 216,359.70 | -48.96 | -31.30 | -85.25 | -43.31 | 53.07 | 62.81 | -78.56 | -56.04 | 0.8108 | -- | 0.00 | -- | 0.5491 | -1.41 | -14.95 | -- | 2.89 | -- |
| OraSure Technologies Inc | 125.70m | -60.24m | 197.27m | 501.00 | -- | 0.549 | -- | 1.57 | -0.8107 | -0.8107 | 1.69 | 5.01 | 0.2834 | 2.07 | 4.91 | 250,904.20 | -13.08 | -0.8506 | -14.16 | -0.9596 | 40.41 | 44.80 | -46.15 | -1.39 | 6.20 | -- | 0.0005 | -- | -54.17 | 3.75 | -136.34 | -- | -16.43 | -- |
| SANUWAVE Health Inc | 41.28m | -7.04m | 205.10m | 46.00 | -- | -- | -- | 4.97 | -0.9346 | -0.9346 | 4.68 | -0.3418 | 1.44 | 1.75 | 11.07 | 897,456.50 | -24.53 | -124.81 | -- | -- | 78.26 | 71.67 | -17.06 | -144.71 | 0.808 | 0.0999 | 1.14 | -- | 59.99 | 99.65 | -21.56 | -- | 55.47 | -- |
| Utah Medical Products Inc | 38.63m | 11.62m | 208.25m | 155.00 | 18.49 | 1.77 | 14.32 | 5.39 | 3.54 | 3.54 | 11.75 | 36.91 | 0.307 | 1.92 | 10.38 | 249,245.20 | 9.24 | 12.08 | 9.48 | 12.53 | 57.10 | 60.88 | 30.08 | 31.04 | 29.36 | -- | 0.00 | 37.43 | -18.56 | -2.70 | -16.60 | -0.8254 | -59.49 | 1.83 |
| Electromed Inc | 68.86m | 8.99m | 209.70m | 177.00 | 24.66 | 4.62 | 20.58 | 3.05 | 1.03 | 1.03 | 7.86 | 5.49 | 1.28 | 4.59 | 2.69 | 389,045.20 | 16.78 | 9.33 | 20.17 | 11.04 | 78.23 | 76.56 | 13.06 | 8.40 | 4.49 | -- | 0.00 | 0.00 | 16.97 | 14.53 | 46.35 | 12.62 | -20.72 | -- |
| KORU Medical Systems Inc | 39.07m | -3.71m | 216.33m | 80.00 | -- | 13.13 | -- | 5.54 | -0.0807 | -0.0807 | 0.8482 | 0.3557 | 1.43 | 3.53 | 7.39 | 488,383.00 | -13.62 | -19.85 | -18.41 | -23.16 | 62.32 | 59.62 | -9.50 | -24.86 | 1.92 | -- | 0.0335 | -- | 17.98 | 7.75 | 55.85 | -- | 25.82 | -- |
| Orchestra Biomed Holdings Inc | 2.82m | -75.10m | 216.82m | 70.00 | -- | 4.96 | -- | 76.94 | -1.82 | -1.82 | 0.0676 | 0.7746 | 0.0313 | 0.6578 | 33.75 | 40,257.14 | -83.39 | -- | -104.85 | -- | 93.01 | -- | -2,665.05 | -- | 4.72 | -- | 0.2451 | -- | -4.42 | -- | -24.23 | -- | -- | -- |
| Cibus Inc | 3.79m | -118.90m | 221.35m | 157.00 | -- | 3.40 | -- | 58.34 | -3.26 | -3.26 | 0.0972 | 0.9588 | 0.0109 | -- | 4.23 | 24,165.61 | -36.11 | -80.24 | -39.32 | -89.98 | -- | -- | -3,322.54 | -1,268.46 | -- | -2.18 | 0.8131 | -- | 134.56 | -10.19 | 6.07 | -- | -22.92 | -- |
| CapsoVision Inc | 13.09m | -22.56m | 228.59m | -- | -- | 11.17 | -- | 17.47 | -0.4873 | -0.4873 | 0.2826 | 0.4368 | -- | -- | -- | -- | -- | -- | -- | -- | 53.13 | -- | -172.37 | -- | 4.50 | -- | 0.00 | -- | 20.54 | -- | -76.01 | -- | -- | -- |
| Simulations Plus Inc | 78.68m | -64.25m | 243.77m | 212.00 | -- | 1.92 | -- | 3.10 | -3.20 | -3.20 | 3.90 | 6.31 | 0.4701 | -- | 4.28 | 371,113.20 | -38.39 | -2.50 | -40.84 | -2.65 | 59.60 | 69.96 | -81.66 | -7.29 | -- | -- | 0.00 | -- | 13.09 | 13.74 | -750.17 | -- | 7.57 | -24.21 |
| 908 Devices Inc | 57.64m | -57.10m | 244.66m | 246.00 | -- | 1.79 | -- | 4.24 | -1.61 | -0.1116 | 1.62 | 3.77 | 0.3123 | 1.76 | 4.17 | 234,296.80 | -30.94 | -18.01 | -37.82 | -19.67 | 49.35 | 52.89 | -99.07 | -78.45 | 3.12 | -- | 0.00 | -- | 18.72 | 27.11 | -98.37 | -- | 8.96 | -- |
| Applied Energetics Inc | 1.15m | -13.02m | 255.85m | 21.00 | -- | -- | -- | 221.88 | -0.0599 | -0.0599 | 0.0053 | -0.0033 | 0.3065 | -- | 7.70 | 54,908.57 | -345.27 | -139.08 | -454.84 | -208.36 | 58.58 | 60.61 | -1,126.59 | -473.16 | -- | -- | -- | -- | -7.78 | -- | -24.71 | -- | 51.42 | -- |
Data as of Feb 18 2026. Currency figures normalised to Orchestra Biomed Holdings Inc's reporting currency: US Dollar USD
34.53%Per cent of shares held by top holders
| Holder | Shares | % Held |
|---|---|---|
| RTW Investments LPas of 30 Sep 2025 | 8.31m | 15.39% |
| Perceptive Advisors LLCas of 30 Sep 2025 | 5.29m | 9.81% |
| The Vanguard Group, Inc.as of 31 Dec 2025 | 1.37m | 2.54% |
| Alyeska Investment Group LPas of 31 Dec 2025 | 1.00m | 1.85% |
| Affinity Asset Advisors LLCas of 31 Dec 2025 | 572.80k | 1.06% |
| Geode Capital Management LLCas of 31 Dec 2025 | 473.36k | 0.88% |
| Knoll Capital Management LPas of 30 Sep 2025 | 455.13k | 0.84% |
| T. Rowe Price Associates, Inc. (IM)as of 30 Sep 2025 | 421.61k | 0.78% |
| Millennium Management LLCas of 30 Sep 2025 | 373.99k | 0.69% |
| DAFNA Capital Management LLCas of 30 Sep 2025 | 363.64k | 0.67% |
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Data from 30 Sep 2025 - 31 Dec 2025Source: FactSet Research Systems Inc.
