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About the company
Applied Therapeutics, Inc. is a clinical-stage biopharmaceutical company. It is focused on developing a pipeline of novel drug candidates against validated molecular targets in indications of high unmet medical need. The Company’s lead drug candidate, govorestat, is a novel central nervous system penetrant Aldose Reductase Inhibitor (ARI) for the treatment of central nervous system (CNS) rare metabolic diseases, including Galactosemia, Sorbitol Dehydrogenase (SORD) Deficiency, and PMM2-CDG. The Company is also developing AT-001, a novel potent ARI, for the treatment of Diabetic Cardiomyopathy (DbCM) a fatal fibrosis of the heart. It has completed a Phase I/II clinical trial evaluating AT-001 in approximately 120 patients with type 2 diabetes, in which no drug-related adverse effects or tolerability issues were observed. The preclinical pipeline also includes AT-003, an ARI designed to cross through the back of the eye when dosed orally, for the treatment of Diabetic retinopathy.
- Revenue in USD (TTM)-477.00k
- Net income in USD-193.56m
- Incorporated2016
- Employees26.00
- LocationApplied Therapeutics Inc545 FIFTH AVENUE, SUITE 1400NEW YORK 10017United StatesUSA
- Phone+1 (212) 220-9226
- Fax+1 (302) 636-5454
- Websitehttps://www.appliedtherapeutics.com/
Peer analysis
- Key Information
- Stock Performance
- Per Share Data
- Efficiency
- Management Effectiveness
- Profitability
- Financial Strength
- Growth Rates
Company | Revenue (TTM) | Net income (TTM) | Market cap | Employees | Price/earnings (TTM) | Price/book value (MRQ) | Price/cash flow (TTM) | Price/sales (TTM) | EPS (excl. extraordinary items, TTM) | EPS (incl. extraordinary items, TTM) | Revenue per share (TTM) | Book value per share (MRQ) | Asset turnover (TTM) | Inventory turnover (TTM) | Receivables turnover (TTM) | Revenues per employee (TTM) | Return on avg assets (TTM) | Return on avg assets (5 yr avg) | Return on investment (TTM) | Return on investment (5 yr avg) | Gross margin (TTM) | Gross margin (5 yr avg) | Net profit margin (TTM) | Net Profit margin (5 yr avg) | Quick ratio (MRQ) | Interest coverage (TTM) | Total debt to capital (MRQ) | Payout ratio (5 yr avg) | Revenue (YOY change %) | Revenue (5 yr growth rate) | Net income (YOY change %) | Net income (5 yr growth rate) | Capital expenditure (5 yr growth rate) | Dividend (5 yr growth rate) |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Larimar Therapeutics Inc | 0.00 | -45.08m | 486.81m | 42.00 | -- | 2.11 | -- | -- | -0.9666 | -0.9666 | 0.00 | 3.62 | 0.00 | -- | -- | 0.00 | -24.56 | -42.22 | -26.04 | -47.14 | -- | -- | -- | -- | -- | -- | 0.00 | -- | -- | -- | -4.51 | -- | 8.71 | -- |
Third Harmonic Bio Inc | 0.00 | -29.60m | 489.35m | 31.00 | -- | 1.83 | -- | -- | -0.7475 | -0.7475 | 0.00 | 6.55 | 0.00 | -- | -- | 0.00 | -10.53 | -- | -10.70 | -- | -- | -- | -- | -- | -- | -- | 0.00 | -- | -- | -- | 12.32 | -- | -- | -- |
Lexeo Therapeutics Inc | 0.00 | -69.42m | 490.56m | 58.00 | -- | 2.68 | -- | -- | -2.71 | -2.71 | 0.00 | 5.56 | 0.00 | -- | -- | 0.00 | -47.71 | -- | -54.30 | -- | -- | -- | -- | -- | -- | -- | 0.0091 | -- | -100.00 | -- | -12.01 | -- | -- | -- |
Astria Therapeutics Inc | 0.00 | -81.63m | 494.22m | 59.00 | -- | 1.81 | -- | -- | -2.32 | -2.32 | 0.00 | 6.70 | 0.00 | -- | -- | 0.00 | -27.34 | -64.48 | -28.18 | -68.34 | -- | -- | -- | -- | -- | -- | 0.00 | -- | -- | -- | -40.62 | -- | -- | -- |
Y-mAbs Therapeutics Inc | 84.50m | -21.67m | 499.38m | 100.00 | -- | 5.03 | -- | 5.91 | -0.496 | -0.496 | 1.93 | 2.26 | 0.6481 | 1.31 | 4.30 | 844,990.00 | -16.62 | -44.23 | -19.95 | -50.45 | 86.53 | -- | -25.64 | -181.13 | 5.67 | -- | 0.00 | -- | 29.96 | -- | 77.58 | -- | -- | -- |
Adaptive Biotechnologies Corp | 174.50m | -215.06m | 499.58m | 709.00 | -- | 1.82 | -- | 2.86 | -1.48 | -1.48 | 1.20 | 1.87 | 0.2472 | 4.52 | 4.78 | 246,124.10 | -30.48 | -19.69 | -34.73 | -22.06 | 57.06 | 67.18 | -123.29 | -122.27 | 4.35 | -- | 0.3238 | -- | -8.11 | 25.06 | -12.52 | -- | 11.11 | -- |
Applied Therapeutics Inc | -477.00k | -193.56m | 500.49m | 26.00 | -- | 7.44 | -- | -- | -1.91 | -1.91 | -0.005 | 0.589 | -0.0053 | -- | -- | -19,080.00 | -213.60 | -140.37 | -604.11 | -240.93 | -- | -- | -- | -4,476.42 | -- | -- | 0.00 | -- | -- | -- | -45.15 | -- | -- | -- |
Northwest Biotherapeutics Inc | 1.34m | -72.21m | 504.94m | 25.00 | -- | -- | -- | 377.95 | -0.0629 | -0.0629 | 0.0012 | -0.0447 | 0.0435 | -- | -- | 53,440.00 | -228.72 | -381.58 | -- | -- | -- | -- | -5,258.91 | -6,479.25 | -- | -10.49 | -- | -- | 14.80 | 36.21 | 38.71 | -- | 77.88 | -- |
ORIC Pharmaceuticals Inc | 0.00 | -101.76m | 507.02m | 102.00 | -- | 1.54 | -- | -- | -1.81 | -1.81 | 0.00 | 4.87 | 0.00 | -- | -- | 0.00 | -35.25 | -33.92 | -37.18 | -35.77 | -- | -- | -- | -- | -- | -- | 0.00 | -- | -- | -- | -12.99 | -- | 10.09 | -- |
Mind Medicine (MindMed) Inc | 0.00 | -125.32m | 513.17m | 57.00 | -- | 2.59 | -- | -- | -2.94 | -2.94 | 0.00 | 2.76 | 0.00 | -- | -- | 0.00 | -58.14 | -- | -73.35 | -- | -- | -- | -- | -- | -- | -- | 0.0675 | -- | -- | -- | -68.55 | -- | -- | -- |
Cassava Sciences Inc | 0.00 | -47.90m | 516.70m | 29.00 | -- | 5.93 | -- | -- | -1.17 | -1.17 | 0.00 | 1.82 | 0.00 | -- | -- | 0.00 | -25.63 | -30.74 | -33.88 | -32.12 | -- | -- | -- | -- | -- | -- | 0.00 | -- | -- | -- | -27.50 | -- | -- | -- |
Contineum Therapeutics Inc | 50.00m | 19.13m | 516.78m | 31.00 | 26.40 | -- | 26.70 | 10.34 | 0.7611 | 0.7611 | 1.99 | 4.66 | -- | -- | -- | 1,612,903.00 | -- | -- | -- | -- | -- | -- | 38.25 | -- | -- | -- | 0.00 | -- | -- | -- | 193.68 | -- | -- | -- |
Erasca Inc | 0.00 | -126.86m | 518.80m | 126.00 | -- | 1.14 | -- | -- | -0.8423 | -0.8423 | 0.00 | 1.91 | 0.00 | -- | -- | 0.00 | -30.29 | -- | -32.45 | -- | -- | -- | -- | -- | -- | -- | 0.00 | -- | -- | -- | 48.50 | -- | -- | -- |
Entrada Therapeutics Inc | 162.87m | 23.49m | 524.62m | 160.00 | 22.62 | 1.77 | 19.58 | 3.22 | 0.6273 | 0.6273 | 4.79 | 8.02 | 0.3302 | -- | 3.89 | 1,024,359.00 | 4.76 | -- | 7.06 | -- | -- | -- | 14.42 | -- | -- | -- | 0.00 | -- | -- | -- | 92.93 | -- | -- | -- |
Corbus Pharmaceuticals Holdings Inc | 0.00 | -33.76m | 530.70m | 19.00 | -- | 5.38 | -- | -- | -6.97 | -6.97 | 0.00 | 9.23 | 0.00 | -- | -- | 0.00 | -38.06 | -86.84 | -49.24 | -130.46 | -- | -- | -- | -769.76 | -- | -15.43 | 0.1179 | -- | -- | -- | -5.33 | -- | -- | -- |
Regenxbio Inc | 86.73m | -260.15m | 532.95m | 344.00 | -- | 1.36 | -- | 6.15 | -5.88 | -5.88 | 1.96 | 7.97 | 0.126 | -- | 5.00 | 252,110.50 | -37.78 | -16.75 | -45.07 | -19.08 | 56.89 | 78.27 | -299.97 | -72.06 | -- | -- | 0.00 | -- | -19.94 | -16.21 | 6.00 | -- | -5.59 | -- |
Holder | Shares | % Held |
---|---|---|
Franklin Advisers, Inc.as of 31 Mar 2024 | 10.56m | 9.25% |
Perceptive Advisors LLCas of 31 Mar 2024 | 8.01m | 7.01% |
Janus Henderson Investors US LLCas of 31 Mar 2024 | 6.41m | 5.61% |
Propel Bio Management LLCas of 31 Mar 2024 | 6.11m | 5.35% |
Knoll Capital Management LPas of 31 Mar 2024 | 5.57m | 4.88% |
Vestal Point Capital LPas of 31 Mar 2024 | 5.11m | 4.47% |
Morgan Stanley & Co. LLCas of 31 Mar 2024 | 3.17m | 2.77% |
The Vanguard Group, Inc.as of 31 Mar 2024 | 2.99m | 2.62% |
Simplify Asset Management, Inc.as of 31 Mar 2024 | 2.82m | 2.47% |
Adage Capital Management LPas of 31 Mar 2024 | 2.65m | 2.32% |