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About the company
Applied Therapeutics, Inc. is a clinical-stage biopharmaceutical company. It is focused on developing a pipeline of novel drug candidates against validated molecular targets in indications of high unmet medical need. The Company’s lead drug candidate, govorestat, is a novel central nervous system penetrant Aldose Reductase Inhibitor (ARI) for the treatment of central nervous system (CNS) rare metabolic diseases, including Galactosemia, Sorbitol Dehydrogenase (SORD) Deficiency, and PMM2-CDG. The Company is also developing AT-001, a novel potent ARI, for the treatment of Diabetic Cardiomyopathy (DbCM) a fatal fibrosis of the heart. It has completed a Phase I/II clinical trial evaluating AT-001 in approximately 120 patients with type 2 diabetes, in which no drug-related adverse effects or tolerability issues were observed. The preclinical pipeline also includes AT-003, an ARI designed to cross through the back of the eye when dosed orally, for the treatment of Diabetic retinopathy.
- Revenue in USD (TTM)-211.00k
- Net income in USD-187.31m
- Incorporated2016
- Employees37.00
- LocationApplied Therapeutics Inc545 FIFTH AVENUE, SUITE 1400NEW YORK 10017United StatesUSA
- Phone+1 (212) 220-9226
- Fax+1 (302) 636-5454
- Websitehttps://www.appliedtherapeutics.com/
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Peer analysis
Key Information
- Key Information
- Stock Performance
- Per Share Data
- Efficiency
- Management Effectiveness
- Profitability
- Financial Strength
- Growth Rates
| Company | Revenue (TTM) | Net income (TTM) | Market cap | Employees | Price/earnings (TTM) | Price/book value (MRQ) | Price/cash flow (TTM) | Price/sales (TTM) | EPS (excl. extraordinary items, TTM) | EPS (incl. extraordinary items, TTM) | Revenue per share (TTM) | Book value per share (MRQ) | Asset turnover (TTM) | Inventory turnover (TTM) | Receivables turnover (TTM) | Revenues per employee (TTM) | Return on avg assets (TTM) | Return on avg assets (5 yr avg) | Return on investment (TTM) | Return on investment (5 yr avg) | Gross margin (TTM) | Gross margin (5 yr avg) | Net profit margin (TTM) | Net Profit margin (5 yr avg) | Quick ratio (MRQ) | Interest coverage (TTM) | Total debt to capital (MRQ) | Payout ratio (5 yr avg) | Revenue (YOY change %) | Revenue (5 yr growth rate) | Net income (YOY change %) | Net income (5 yr growth rate) | Capital expenditure (5 yr growth rate) | Dividend (5 yr growth rate) |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Septerna Inc | 840.00 | -10.27k | 915.24m | 68.00 | -- | -- | -- | 1,089,573.00 | -0.0003 | -0.0003 | 0.00002 | 0.0037 | -- | -- | -- | 12.35 | -- | -- | -- | -- | -- | -- | -792.86 | -- | -- | -- | 0.00 | -- | -- | -- | 102.06 | -- | -- | -- |
| Lenz Therapeutics Inc | 0.00 | -60.04m | 943.83m | 6.00 | -- | 4.38 | -- | -- | -7.08 | -7.08 | 0.00 | 7.83 | 0.00 | -- | -- | 0.00 | -24.49 | -- | -25.55 | -- | -- | -- | -- | -- | -- | -- | 0.00 | -- | -- | -- | -23.35 | -- | -- | -- |
| Zymeworks Inc | 62.20m | -113.67m | 946.15m | 294.00 | -- | 2.62 | -- | 15.21 | -1.51 | -1.51 | 0.8306 | 5.23 | 0.1192 | -- | 1.37 | 228,672.80 | -21.79 | -22.58 | -25.64 | -26.90 | -- | -- | -182.75 | -91.17 | -- | -- | 0.00009 | -- | -81.57 | 7.47 | -195.44 | -- | 3.58 | -- |
| Upstream Bio Inc | -100.00bn | -100.00bn | 954.02m | 38.00 | -- | -- | -- | -- | -- | -- | -- | 4.30 | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | 0.00 | -- | 96.37 | -- | -60.28 | -- | -- | -- |
| Vir Biotechnology Inc | 78.62m | -533.34m | 957.15m | 587.00 | -- | 0.7658 | -- | 12.17 | -3.92 | -3.92 | 0.5794 | 9.08 | 0.0444 | -- | -- | 133,931.90 | -30.10 | -0.6081 | -32.71 | -0.7192 | 98.78 | -- | -678.40 | -1.53 | -- | -- | 0.00 | -- | -94.67 | 51.87 | -219.24 | -- | 16.77 | -- |
| Cogent Biosciences Inc | 0.00 | -242.30m | 982.87m | 164.00 | -- | 4.86 | -- | -- | -2.48 | -2.48 | 0.00 | 2.85 | 0.00 | -- | -- | 0.00 | -65.53 | -49.53 | -74.36 | -54.94 | -- | -- | -- | -1,684.44 | -- | -- | 0.00 | -- | -- | -- | -37.20 | -- | 38.48 | -- |
| 89bio Inc | 0.00 | -288.96m | 985.34m | 70.00 | -- | 2.35 | -- | -- | -2.91 | -2.91 | 0.00 | 3.56 | 0.00 | -- | -- | 0.00 | -62.93 | -45.50 | -67.67 | -49.31 | -- | -- | -- | -- | -- | -- | 0.0859 | -- | -- | -- | -39.37 | -- | -36.58 | -- |
| Applied Therapeutics Inc | -211.00k | -187.31m | 1.08bn | 37.00 | -- | 183.07 | -- | -- | -1.53 | -1.53 | -0.0017 | 0.0506 | -0.0028 | -- | -- | -8,440.00 | -246.85 | -140.37 | -- | -240.93 | -- | -- | -- | -4,476.42 | -- | -- | 0.00 | -- | -- | -- | -45.15 | -- | -- | -- |
| Gyre Therapeutics Inc | 191.34m | -76.96m | 1.10bn | 593.00 | -- | 15.95 | -- | 5.74 | -0.2281 | -0.2281 | 1.35 | 0.7366 | 2.83 | -- | 19.64 | 322,656.00 | -95.21 | -73.59 | -154.33 | -99.94 | 96.16 | -- | -33.64 | -205.62 | 3.29 | -- | 0.00 | -- | 14,188.41 | 616.69 | -1,027.55 | -- | 86.95 | -- |
| Pharvaris NV | 0.00 | -138.46m | 1.14bn | 82.00 | -- | 3.66 | -- | -- | -2.71 | -2.71 | 0.00 | 5.76 | 0.00 | -- | -- | 0.00 | -54.80 | -36.09 | -58.76 | -38.27 | -- | -- | -- | -- | -- | -41.69 | 0.0004 | -- | -- | -- | -32.15 | -- | -- | -- |
| Rocket Pharmaceuticals Inc | 0.00 | -258.08m | 1.17bn | 268.00 | -- | 3.53 | -- | -- | -2.75 | -2.75 | 0.00 | 3.62 | 0.00 | -- | -- | 0.00 | -52.01 | -35.26 | -56.17 | -37.49 | -- | -- | -- | -- | -- | -- | 0.0605 | -- | -- | -- | -10.70 | -- | 62.52 | -- |
| Arcutis Biotherapeutics Inc | 138.71m | -195.54m | 1.20bn | 296.00 | -- | 7.65 | -- | 8.64 | -1.79 | -1.79 | 1.23 | 1.34 | 0.3799 | 1.04 | 3.49 | 468,608.10 | -53.55 | -65.64 | -75.79 | -71.72 | 89.57 | -- | -140.97 | -1,513.03 | 2.38 | -6.19 | 0.5664 | -- | 1,517.09 | -- | 15.83 | -- | -- | -- |
| CareDx Inc | 312.78m | -143.56m | 1.21bn | 635.00 | -- | 4.39 | -- | 3.87 | -2.70 | -2.70 | 5.95 | 5.15 | 0.6395 | 5.75 | 5.29 | 492,559.10 | -29.35 | -17.54 | -34.84 | -20.85 | 65.77 | 65.50 | -45.90 | -27.78 | 3.87 | -- | 0.00 | -- | -12.89 | 29.63 | -148.37 | -- | 5.01 | -- |
| Ardelyx Inc | 251.85m | -72.58m | 1.21bn | 267.00 | -- | 7.66 | -- | 4.82 | -0.3113 | -0.3113 | 1.08 | 0.6682 | 0.7664 | 3.76 | 5.22 | 943,254.70 | -22.09 | -46.14 | -26.72 | -57.32 | 85.16 | 88.15 | -28.82 | -240.87 | 3.87 | -5.94 | 0.3888 | -- | 138.61 | 116.66 | 1.70 | -- | 2.04 | -- |
| Enliven Therapeutics Inc | 0.00 | -85.21m | 1.24bn | 57.00 | -- | 4.16 | -- | -- | -1.91 | -1.91 | 0.00 | 6.10 | 0.00 | -- | -- | 0.00 | -29.41 | -42.26 | -30.97 | -46.62 | -- | -- | -- | -- | -- | -- | 0.00 | -- | -- | -- | -4,910.75 | -- | -- | -- |
Data as of Nov 22 2024. Currency figures normalised to Applied Therapeutics Inc's reporting currency: US Dollar USD
58.70%Per cent of shares held by top holders
| Holder | Shares | % Held |
|---|---|---|
| Janus Henderson Investors US LLCas of 30 Sep 2024 | 10.54m | 9.18% |
| Morgan Stanley & Co. LLCas of 30 Sep 2024 | 9.89m | 8.62% |
| Perceptive Advisors LLCas of 30 Sep 2024 | 8.01m | 6.97% |
| Franklin Advisers, Inc.as of 30 Sep 2024 | 6.80m | 5.92% |
| Propel Bio Management LLCas of 30 Sep 2024 | 6.57m | 5.72% |
| BlackRock Fund Advisorsas of 30 Sep 2024 | 6.40m | 5.58% |
| Knoll Capital Management LPas of 30 Sep 2024 | 5.57m | 4.85% |
| The Vanguard Group, Inc.as of 30 Sep 2024 | 5.08m | 4.42% |
| DWS Investments (UK) Ltd.as of 30 Sep 2024 | 4.44m | 3.86% |
| Adage Capital Management LPas of 30 Sep 2024 | 4.11m | 3.58% |
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Data from 30 Sep 2024 - 30 Sep 2024Source: FactSet Research Systems Inc.
