Equities

Applied Therapeutics Inc

Applied Therapeutics Inc

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Health CarePharmaceuticals and Biotechnology
  • Price (USD)4.34
  • Today's Change0.11 / 2.60%
  • Shares traded48.86k
  • 1 Year change+185.53%
  • Beta1.9170
Data delayed at least 15 minutes, as of Apr 26 2024 16:04 BST.
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About the company

Applied Therapeutics, Inc. is a clinical-stage biopharmaceutical company. It is focused on developing a pipeline of novel drug candidates against validated molecular targets in indications of high unmet medical need. The Company’s lead drug candidate, govorestat, is a novel central nervous system penetrant Aldose Reductase Inhibitor (ARI) for the treatment of central nervous system (CNS) rare metabolic diseases, including Galactosemia, Sorbitol Dehydrogenase (SORD) Deficiency, and PMM2-CDG. The Company is also developing AT-001, a novel potent ARI, for the treatment of Diabetic Cardiomyopathy (DbCM) a fatal fibrosis of the heart. It has completed a Phase I/II clinical trial evaluating AT-001 in approximately 120 patients with type 2 diabetes, in which no drug-related adverse effects or tolerability issues were observed. The preclinical pipeline also includes AT-003, an ARI designed to cross through the back of the eye when dosed orally, for the treatment of Diabetic retinopathy.

  • Revenue in USD (TTM)9.99m
  • Net income in USD-119.76m
  • Incorporated2016
  • Employees25.00
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Peer analysis

Key Information
CompanyRevenue (TTM)Net income (TTM)Market capEmployeesPrice/earnings (TTM)Price/book value (MRQ)Price/cash flow (TTM)Price/sales (TTM)EPS (excl. extraordinary items, TTM)EPS (incl. extraordinary items, TTM)Revenue per share (TTM)Book value per share (MRQ)Asset turnover (TTM)Inventory turnover (TTM)Receivables turnover (TTM)Revenues per employee (TTM)Return on avg assets (TTM)Return on avg assets (5 yr avg)Return on investment (TTM)Return on investment (5 yr avg)Gross margin (TTM)Gross margin
(5 yr avg)
Net profit margin (TTM)Net Profit margin
(5 yr avg)
Quick ratio (MRQ)Interest coverage (TTM)Total debt to capital (MRQ)Payout ratio
(5 yr avg)
Revenue
(YOY change %)
Revenue
(5 yr growth rate)
Net income
(YOY change %)
Net income
(5 yr growth rate)
Capital expenditure
(5 yr growth rate)
Dividend
(5 yr growth rate)
Avid Bioservices Inc140.94m-11.45m462.91m365.00--2.52--3.28-0.1816-0.18162.232.900.31443.185.49386,131.50-2.5510.73-3.1114.0112.5222.72-8.1225.920.8529-3.320.45020.0024.8122.72-99.56--82.90--
Shattuck Labs Inc1.66m-87.30m464.30m75.00--3.19--280.21-2.05-2.050.03893.060.0091----22,093.33-47.85-29.14-53.15-32.42-----5,268.44-565.33----0.00--154.14-40.6214.37---19.15--
Humacyte Inc0.00-110.78m464.43m183.00--29.85-----1.07-1.070.000.13070.00----0.00-66.63---75.23-------------88.380.5819---100.00---825.83------
Nkarta Inc0.00-117.50m478.70m150.00--1.23-----2.40-2.400.005.560.00----0.00-27.59-32.39-29.14-34.05-------372,519.20----0.00-------3.22--106.05--
Celcuity Inc0.00-63.78m480.25m55.00--2.88-----2.70-2.700.005.480.00----0.00-34.76-37.32-36.88-39.16------------0.2095-------57.99---31.12--
Applied Therapeutics Inc9.99m-119.76m483.24m25.00------48.36-1.42-1.420.1288-0.2020.2145----399,720.00-257.01-140.37---240.93-----1,198.47-4,476.42-------------45.15------
PetIQ Inc1.10bn2.13m484.95m1.93k265.932.179.880.44010.06140.061435.697.521.315.638.46570,079.100.301-4.320.3777-5.2322.9420.050.2304-3.661.431.740.6671--19.5815.83104.42--4.96--
Allogene Therapeutics Inc95.00k-327.27m487.41m232.00--0.94--5,130.68-2.09-2.090.00063.040.0001----409.48-44.70-28.46-47.65-30.21-----344,489.50-1,123.44----0.00---39.10--3.86---14.06--
Arbutus Biopharma Corp18.14m-72.85m490.08m73.00--4.36--27.01-0.4386-0.43860.10930.62410.1068--11.60248,506.80-42.88-52.62-51.22-58.11-----401.57-537.81----0.00---53.5125.00-4.89---2.40--
Adlai Nortye Ltd (ADR)0.00-62.74m496.68m129.00---------1.68-1.680.00-6.83------0.00-------------------------100.00---3.73------
Absci Corp5.72m-110.57m502.46m155.00--2.35--87.87-1.20-1.200.06211.890.0212--3.0636,890.32-41.08---46.22-------1,933.65-----93.250.0467---0.5046---5.40------
Exscientia PLC (ADR)25.12m-182.64m503.22m483.00--1.13--20.03-1.45-1.450.19993.540.03461,096.089.8652,018.25-25.16---29.09---36.47---726.94--6.22--0.0505---26.24---22.94------
Astria Therapeutics Inc0.00-72.89m503.46m59.00--2.55-----2.34-2.340.005.920.00----0.00-30.04-64.48-31.37-68.34------------0.00-------40.62------
Phibro Animal Health Corp982.01m14.80m503.86m1.92k34.051.8610.150.51310.36540.365424.246.691.022.376.49511,465.601.535.461.876.8330.4331.411.515.111.602.500.636942.993.783.59-33.69-13.5622.803.71
Data as of Apr 26 2024. Currency figures normalised to Applied Therapeutics Inc's reporting currency: US Dollar USD

Institutional shareholders

40.77%Per cent of shares held by top holders
HolderShares% Held
Franklin Advisers, Inc.as of 31 Dec 20237.02m6.63%
Janus Henderson Investors US LLCas of 01 Mar 20246.41m6.06%
Knoll Capital Management LPas of 31 Dec 20235.47m5.17%
Propel Bio Management LLCas of 31 Dec 20235.37m5.08%
Vestal Point Capital LPas of 31 Dec 20234.16m3.92%
Perceptive Advisors LLCas of 31 Dec 20234.08m3.85%
The Vanguard Group, Inc.as of 31 Dec 20233.21m3.03%
Alyeska Investment Group LPas of 31 Dec 20232.60m2.46%
Fidelity Management & Research Co. LLCas of 31 Dec 20232.43m2.29%
Simplify Asset Management, Inc.as of 31 Dec 20232.42m2.28%
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Data from 31 Dec 2023 - 31 Dec 2023Source: FactSet Research Systems Inc.
Data Provided by LSEG
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