Equities

Bicycle Therapeutics PLC

Bicycle Therapeutics PLC

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Health CarePharmaceuticals and Biotechnology
  • Price (USD)20.26
  • Today's Change-0.10 / -0.49%
  • Shares traded962.94k
  • 1 Year change+50.52%
  • Beta0.8750
Data delayed at least 15 minutes, as of Nov 21 2024 21:00 GMT.
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About the company

Bicycle Therapeutics plc is a United Kingdom-based clinical-stage biopharmaceutical company developing a novel class of medicines, referred to as Bicycle molecules, for diseases that are underserved by existing therapeutics. Bicycle molecules are fully synthetic short peptides constrained with small molecule scaffolds to form two loops that stabilize their structural geometry. The Company is evaluating BT8009, a Bicycle Toxin Conjugate (BTC) targeting Nectin-4, a well-validated tumor antigen; BT5528, a BTC targeting EphA2, a historically undruggable target, and BT7480, a Bicycle Tumor-Targeted Immune Cell Agonist (Bicycle TICA) targeting Nectin-4 and agonizing CD137, in Company-sponsored clinical trials. Additionally, the Company is developing Bicycle Radio Conjugates (BRC) for radiopharmaceutical use and, through various partnerships, is exploring the use of Bicycle technology to develop therapies for diseases beyond oncology. Its product candidates also include BT1718 and BT7455.

  • Revenue in USD (TTM)36.90m
  • Net income in USD-166.28m
  • Incorporated2017
  • Employees284.00
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Peer analysis

Key Information
CompanyRevenue (TTM)Net income (TTM)Market capEmployeesPrice/earnings (TTM)Price/book value (MRQ)Price/cash flow (TTM)Price/sales (TTM)EPS (excl. extraordinary items, TTM)EPS (incl. extraordinary items, TTM)Revenue per share (TTM)Book value per share (MRQ)Asset turnover (TTM)Inventory turnover (TTM)Receivables turnover (TTM)Revenues per employee (TTM)Return on avg assets (TTM)Return on avg assets (5 yr avg)Return on investment (TTM)Return on investment (5 yr avg)Gross margin (TTM)Gross margin
(5 yr avg)
Net profit margin (TTM)Net Profit margin
(5 yr avg)
Quick ratio (MRQ)Interest coverage (TTM)Total debt to capital (MRQ)Payout ratio
(5 yr avg)
Revenue
(YOY change %)
Revenue
(5 yr growth rate)
Net income
(YOY change %)
Net income
(5 yr growth rate)
Capital expenditure
(5 yr growth rate)
Dividend
(5 yr growth rate)
Maravai Lifesciences Holdings Inc276.92m-224.66m1.25bn580.00--3.63--4.52-1.65-1.652.041.370.15622.987.43426,030.80-18.2312.67-23.3915.4646.3674.79-116.6837.329.94-1.470.47460.00-67.2818.47-154.05--78.56--
Aurinia Pharmaceuticals Inc220.36m-22.55m1.26bn300.00--3.23--5.70-0.1582-0.15821.532.710.39910.78545.92734,536.70-4.08-25.97-4.74-28.2487.25---10.23-137.645.11--0.1725--30.95227.9027.88--57.11--
Novavax Inc885.19m-284.86m1.29bn1.54k------1.45-2.26-2.266.00-3.290.52548.198.10573,683.10-16.91-46.06-79.12-269.5763.79---32.18-75.940.9272-17.46-----50.3695.6817.16--108.28--
ARS Pharmaceuticals Inc2.57m-49.10m1.30bn146.00--6.47--505.09-0.5076-0.50760.02662.070.011----107,000.00-21.07-20.37-22.40-21.3276.17---1,912.15-17,491.7512.52--0.00---97.72---56.75---17.18--
Arcus Biosciences Inc263.00m-270.00m1.31bn577.00--2.31--4.97-3.15-3.153.066.170.2153--6.83455,805.90-22.10-15.85-26.63-18.25-----102.66-103.46----0.0768--4.4669.54-14.98--45.01--
Syndax Pharmaceuticals Inc16.00m-297.06m1.33bn112.00--3.64--83.22-3.63-3.630.19494.280.0388--3.60142,857.10-72.01-27.90-81.78-30.15-----1,856.64-324.34----0.00003-------40.19------
Day One Biopharmaceuticals Inc101.95m-84.29m1.35bn174.00--2.42--13.20-1.02-1.021.145.510.2009----657,761.30-16.61---17.73--97.75---82.68--14.55--0.00-------32.87------
MiMedx Group Inc342.81m90.79m1.35bn895.0018.597.4913.613.950.49610.46012.001.231.582.636.65383,022.3044.93-4.1456.00-5.9083.3783.6128.37-2.703.5322.350.0951--20.03-2.19310.29---26.47--
Praxis Precision Medicines Inc1.61m-151.02m1.36bn82.00--3.40--848.40-10.29-10.290.105821.520.0061----19,573.17-57.75-74.04-63.81-85.12-----9,409.22-24,589.25----0.00------42.40---4.52--
Spyre Therapeutics Inc0.00-214.90m1.39bn60.00--8.09-----7.44-7.440.006.370.00----0.00-68.40-101.87-81.72-118.83-------2,949.59----0.00---61.96-25.61-304.21------
Bicycle Therapeutics PLC (ADR)36.90m-166.28m1.40bn284.00--1.68--37.91-3.28-3.280.716312.040.0451--0.9806129,922.50-20.33-29.45-22.03-32.98-----450.64-571.36----0.0002--86.5230.47-60.28--19.82--
Intellia Therapeutics Inc43.09m-522.28m1.40bn526.00--1.46--32.53-5.45-5.450.45099.460.0357--5.6281,912.55-43.22-31.34-47.07-34.53-----1,212.19-654.71----0.00---30.403.57-1.48--17.08--
Cassava Sciences Inc0.00-17.66m1.54bn29.00--9.26-----0.3772-0.37720.003.470.00----0.00-8.91-30.74-10.98-32.12------------0.00-------27.50------
Neumora Therapeutics Inc0.00-293.70m1.55bn108.00--4.85-----1.77-1.770.002.000.00----0.00-65.46---70.23--------------0.00-------80.23------
BioCryst Pharmaceuticals Inc412.58m-123.82m1.55bn536.00------3.76-0.6073-0.60732.01-2.260.81360.42976.54769,736.90-24.42-47.95-32.17-64.8998.0697.06-30.01-114.942.73-0.4882.29--22.3774.218.33--42.73--
Data as of Nov 21 2024. Currency figures normalised to Bicycle Therapeutics PLC's reporting currency: US Dollar USD

Institutional shareholders

53.60%Per cent of shares held by top holders
HolderShares% Held
Baker Bros. Advisors LPas of 30 Sep 20249.40m19.79%
Deep Track Capital LPas of 30 Sep 20243.55m7.47%
RA Capital Management LPas of 30 Sep 20242.25m4.74%
Armistice Capital LLCas of 30 Sep 20241.96m4.12%
Westfield Capital Management Co. LPas of 30 Sep 20241.85m3.90%
T. Rowe Price Associates, Inc. (IM)as of 30 Sep 20241.72m3.63%
Tybourne Capital Management (HK) Ltd.as of 30 Sep 20241.39m2.94%
Morgan Stanley & Co. LLCas of 30 Sep 20241.28m2.70%
Candriam Belgium SAas of 30 Sep 20241.05m2.21%
Polar Capital LLPas of 30 Sep 20241.00m2.11%
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Data from 30 Sep 2024 - 30 Sep 2024Source: FactSet Research Systems Inc.
Data Provided by LSEG
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