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About the company
Syndax Pharmaceuticals, Inc. is a clinical-stage biopharmaceutical company. It is focused on developing pipeline of cancer therapies. Its product candidates include revumenib, and axatilimab. It is developing revumenib, a potent, selective, small molecule inhibitor of the menin-MLL binding interaction for the treatment of KMT2A rearranged also known as mixed lineage leukemia rearranged, acute leukemias including acute lymphoblastic leukemia and acute myeloid leukemia (AML), and necleophosmin 1, also known as NPM1, mutant A. It is also exploring the use of revumenib as a treatment in solid tumors, specifically its activity in metastatic colorectal cancer. It is also developing axatilimab, a monoclonal antibody that blocks the colony stimulating factor 1 receptor (CSF-1R) in chronic graft-versus-host disease (cGVHD), as well as idiopathic pulmonary fibrosis. Entinostat is its oral, small molecule product candidate that has direct effects on both cancer cells and immune regulatory cells.
- Revenue in USD (TTM)16.00m
- Net income in USD-297.06m
- Incorporated2005
- Employees112.00
- LocationSyndax Pharmaceuticals Inc35 Gatehouse Drive, Building D, Floor 3WALTHAM 02451United StatesUSA
- Phone+1 (781) 419-1400
- Fax+1 (781) 419-1420
- Websitehttps://syndax.com/
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Peer analysis
Key Information
- Key Information
- Stock Performance
- Per Share Data
- Efficiency
- Management Effectiveness
- Profitability
- Financial Strength
- Growth Rates
| Company | Revenue (TTM) | Net income (TTM) | Market cap | Employees | Price/earnings (TTM) | Price/book value (MRQ) | Price/cash flow (TTM) | Price/sales (TTM) | EPS (excl. extraordinary items, TTM) | EPS (incl. extraordinary items, TTM) | Revenue per share (TTM) | Book value per share (MRQ) | Asset turnover (TTM) | Inventory turnover (TTM) | Receivables turnover (TTM) | Revenues per employee (TTM) | Return on avg assets (TTM) | Return on avg assets (5 yr avg) | Return on investment (TTM) | Return on investment (5 yr avg) | Gross margin (TTM) | Gross margin (5 yr avg) | Net profit margin (TTM) | Net Profit margin (5 yr avg) | Quick ratio (MRQ) | Interest coverage (TTM) | Total debt to capital (MRQ) | Payout ratio (5 yr avg) | Revenue (YOY change %) | Revenue (5 yr growth rate) | Net income (YOY change %) | Net income (5 yr growth rate) | Capital expenditure (5 yr growth rate) | Dividend (5 yr growth rate) |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Pharvaris NV | 0.00 | -137.72m | 1.20bn | 82.00 | -- | 3.89 | -- | -- | -2.69 | -2.69 | 0.00 | 5.72 | 0.00 | -- | -- | 0.00 | -54.80 | -36.09 | -58.76 | -38.27 | -- | -- | -- | -- | -- | -41.69 | 0.0004 | -- | -- | -- | -32.15 | -- | -- | -- |
| CareDx Inc | 312.78m | -143.56m | 1.24bn | 635.00 | -- | 4.50 | -- | 3.97 | -2.70 | -2.70 | 5.95 | 5.15 | 0.6395 | 5.75 | 5.29 | 492,559.10 | -29.35 | -17.54 | -34.84 | -20.85 | 65.77 | 65.50 | -45.90 | -27.78 | 3.87 | -- | 0.00 | -- | -12.89 | 29.63 | -148.37 | -- | 5.01 | -- |
| Ardelyx Inc | 251.85m | -72.58m | 1.26bn | 267.00 | -- | 7.95 | -- | 4.99 | -0.3113 | -0.3113 | 1.08 | 0.6682 | 0.7664 | 3.76 | 5.22 | 943,254.70 | -22.09 | -46.14 | -26.72 | -57.32 | 85.16 | 88.15 | -28.82 | -240.87 | 3.87 | -5.94 | 0.3888 | -- | 138.61 | 116.66 | 1.70 | -- | 2.04 | -- |
| Aurinia Pharmaceuticals Inc | 220.36m | -22.55m | 1.27bn | 300.00 | -- | 3.27 | -- | 5.76 | -0.1582 | -0.1582 | 1.53 | 2.71 | 0.3991 | 0.7854 | 5.92 | 734,536.70 | -4.08 | -25.97 | -4.74 | -28.24 | 87.25 | -- | -10.23 | -137.64 | 5.11 | -- | 0.1725 | -- | 30.95 | 227.90 | 27.88 | -- | 57.11 | -- |
| Cassava Sciences Inc | 0.00 | -17.66m | 1.27bn | 29.00 | -- | 7.62 | -- | -- | -0.3772 | -0.3772 | 0.00 | 3.47 | 0.00 | -- | -- | 0.00 | -8.91 | -30.74 | -10.98 | -32.12 | -- | -- | -- | -- | -- | -- | 0.00 | -- | -- | -- | -27.50 | -- | -- | -- |
| Rocket Pharmaceuticals Inc | 0.00 | -258.08m | 1.29bn | 268.00 | -- | 3.90 | -- | -- | -2.75 | -2.75 | 0.00 | 3.62 | 0.00 | -- | -- | 0.00 | -52.01 | -35.26 | -56.17 | -37.49 | -- | -- | -- | -- | -- | -- | 0.0605 | -- | -- | -- | -10.70 | -- | 62.52 | -- |
| Maravai Lifesciences Holdings Inc | 276.92m | -224.66m | 1.32bn | 580.00 | -- | 3.82 | -- | 4.75 | -1.65 | -1.65 | 2.04 | 1.37 | 0.1562 | 2.98 | 7.43 | 426,030.80 | -18.23 | 12.67 | -23.39 | 15.46 | 46.36 | 74.79 | -116.68 | 37.32 | 9.94 | -1.47 | 0.4746 | 0.00 | -67.28 | 18.47 | -154.05 | -- | 78.56 | -- |
| Arcus Biosciences Inc | 263.00m | -270.00m | 1.35bn | 577.00 | -- | 2.38 | -- | 5.11 | -3.15 | -3.15 | 3.06 | 6.17 | 0.2153 | -- | 6.83 | 455,805.90 | -22.10 | -15.85 | -26.63 | -18.25 | -- | -- | -102.66 | -103.46 | -- | -- | 0.0768 | -- | 4.46 | 69.54 | -14.98 | -- | 45.01 | -- |
| MiMedx Group Inc | 342.81m | 90.79m | 1.35bn | 895.00 | 18.55 | 7.47 | 13.58 | 3.94 | 0.4961 | 0.4601 | 2.00 | 1.23 | 1.58 | 2.63 | 6.65 | 383,022.30 | 44.93 | -4.14 | 56.00 | -5.90 | 83.37 | 83.61 | 28.37 | -2.70 | 3.53 | 22.35 | 0.0951 | -- | 20.03 | -2.19 | 310.29 | -- | -26.47 | -- |
| Novavax Inc | 885.19m | -284.86m | 1.36bn | 1.54k | -- | -- | -- | 1.53 | -2.26 | -2.26 | 6.00 | -3.29 | 0.5254 | 8.19 | 8.10 | 573,683.10 | -16.91 | -46.06 | -79.12 | -269.57 | 63.79 | -- | -32.18 | -75.94 | 0.9272 | -17.46 | -- | -- | -50.36 | 95.68 | 17.16 | -- | 108.28 | -- |
| ARS Pharmaceuticals Inc | 2.57m | -49.10m | 1.36bn | 146.00 | -- | 6.77 | -- | 528.50 | -0.5076 | -0.5076 | 0.0266 | 2.07 | 0.011 | -- | -- | 107,000.00 | -21.07 | -20.37 | -22.40 | -21.32 | 76.17 | -- | -1,912.15 | -17,491.75 | 12.52 | -- | 0.00 | -- | -97.72 | -- | -56.75 | -- | -17.18 | -- |
| Syndax Pharmaceuticals Inc | 16.00m | -297.06m | 1.37bn | 112.00 | -- | 3.76 | -- | 85.84 | -3.63 | -3.63 | 0.1949 | 4.28 | 0.0388 | -- | 3.60 | 142,857.10 | -72.01 | -27.90 | -81.78 | -30.15 | -- | -- | -1,856.64 | -324.34 | -- | -- | 0.00003 | -- | -- | -- | -40.19 | -- | -- | -- |
| Day One Biopharmaceuticals Inc | 101.95m | -84.29m | 1.38bn | 174.00 | -- | 2.49 | -- | 13.57 | -1.02 | -1.02 | 1.14 | 5.51 | 0.2009 | -- | -- | 657,761.30 | -16.61 | -- | -17.73 | -- | 97.75 | -- | -82.68 | -- | 14.55 | -- | 0.00 | -- | -- | -- | -32.87 | -- | -- | -- |
| Praxis Precision Medicines Inc | 1.61m | -151.02m | 1.39bn | 82.00 | -- | 3.46 | -- | 865.12 | -10.29 | -10.29 | 0.1058 | 21.52 | 0.0061 | -- | -- | 19,573.17 | -57.75 | -74.04 | -63.81 | -85.12 | -- | -- | -9,409.22 | -24,589.25 | -- | -- | 0.00 | -- | -- | -- | 42.40 | -- | -4.52 | -- |
| Bicycle Therapeutics PLC (ADR) | 36.90m | -166.28m | 1.42bn | 284.00 | -- | 1.71 | -- | 38.44 | -3.28 | -3.28 | 0.7163 | 12.04 | 0.0451 | -- | 0.9806 | 129,922.50 | -20.33 | -29.45 | -22.03 | -32.98 | -- | -- | -450.64 | -571.36 | -- | -- | 0.0002 | -- | 86.52 | 30.47 | -60.28 | -- | 19.82 | -- |
| Intellia Therapeutics Inc | 43.09m | -522.28m | 1.45bn | 526.00 | -- | 1.51 | -- | 33.71 | -5.45 | -5.45 | 0.4509 | 9.46 | 0.0357 | -- | 5.62 | 81,912.55 | -43.22 | -31.34 | -47.07 | -34.53 | -- | -- | -1,212.19 | -654.71 | -- | -- | 0.00 | -- | -30.40 | 3.57 | -1.48 | -- | 17.08 | -- |
Data as of Nov 25 2024. Currency figures normalised to Syndax Pharmaceuticals Inc's reporting currency: US Dollar USD
48.33%Per cent of shares held by top holders
| Holder | Shares | % Held |
|---|---|---|
| BlackRock Fund Advisorsas of 30 Sep 2024 | 6.78m | 7.97% |
| Kynam Capital Management LPas of 30 Sep 2024 | 5.84m | 6.87% |
| Wellington Management Co. LLPas of 30 Sep 2024 | 4.85m | 5.70% |
| The Vanguard Group, Inc.as of 30 Sep 2024 | 4.67m | 5.48% |
| Eversept Partners LPas of 30 Sep 2024 | 4.11m | 4.82% |
| Avoro Capital Advisor LLCas of 30 Sep 2024 | 3.89m | 4.57% |
| SSgA Funds Management, Inc.as of 30 Sep 2024 | 3.77m | 4.43% |
| Point72 Asset Management LPas of 30 Sep 2024 | 2.79m | 3.28% |
| Avidity Partners Management LPas of 30 Sep 2024 | 2.46m | 2.89% |
| Geode Capital Management LLCas of 30 Sep 2024 | 1.98m | 2.32% |
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Data from 30 Sep 2024 - 30 Sep 2024Source: FactSet Research Systems Inc.
